Proximity ligation-transcription circuit-powered exponential amplifications for single-molecule monitoring of telomerase in human cells

We develop a new strategy for single-molecule monitoring of telomerase based on proximity ligation-transcription circuit-powered exponential amplifications. This strategy exhibits high sensitivity with a detection limit of 0.1 aM for the synthetic telomerase product TPC4 in vitro and 1 HeLa cell in...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2023-01, Vol.59 (9), p.1181-1184
Hauptverfasser:	Wang, Li-juan, Lv, Meng-meng, Hu, Jin-ping, Liu, Meng, Zhang, Chun-yang
Format:	Artikel
Sprache:	eng
Schlagworte:	Amplification Circuits HeLa Cells Humans Monitoring Telomerase Telomerase - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!