PL‐101‐WK, a novel tryptophan‐ and lysine‐rich peptide with antimicrobial activity against Staphylococcus aureus

Designing short antimicrobial peptides (AMPs), which are active against drug‐resistant bacteria, is a promising way to find new therapeutic agents. In this research, a novel short AMP, PL‐101‐WK, was designed based on PL‐101 (a derivative of plicatamide). Here, the substitution of Phe and His with T...

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Veröffentlicht in:	Peptide science (Hoboken, N.J.) N.J.), 2023-01, Vol.115 (1), p.n/a
Hauptverfasser:	Shahraki, Parvin Zadeh, Farrokh, Parisa
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibacterial activity Antimicrobial activity Antimicrobial agents antimicrobial peptide Antimicrobial peptides Lysine Minimum inhibitory concentration Peptides Physicochemical properties PL‐101 Sodium chloride Staphylococcus aureus Strains (organisms) Thermal stability Tryptophan
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