Cationic Ru(η6‐p‐cymene) Complexes of 3‐Hydroxy‐4‐pyr(id)ones – Lipophilic Triphenylphosphine as Co‐Ligand Is Key to Highly Stable and Cytotoxic Anticancer Agents

Ru(arene)[3‐hydroxy‐4(1H)‐pyr(id)one]Cl complexes are known to be converted intodinuclear Ru(arene) compounds with three hydroxido bridges in aqueous solution. In an attempt to obtain anticancer Ru(arene) complexes of 3‐hydroxy‐4(1H)‐pyr(id)one ligands that are stable in aqueous solution, triphenylp...

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Veröffentlicht in:	European journal of inorganic chemistry 2017-03, Vol.2017 (12), p.1721-1727
Hauptverfasser:	Parveen, Shahida, Hanif, Muhammad, Movassaghi, Sanam, Sullivan, Matthew P., Kubanik, Mario, Shaheen, Muhammad Ashraf, Söhnel, Tilo, Jamieson, Stephen M. F., Hartinger, Christian G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticancer properties Antitumor agents Aqueous solutions Bioorganometallic compounds Cancer Cations Cytotoxicity Histidine Inorganic chemistry Ligands Lipophilicity Methionine O ligands Phosphane ligands Phosphines Ruthenium Toxicity
Online-Zugang:	Volltext
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