Lidocaine versus dexamethasone for reduction of sore throat after general anesthesia: a comparative study
Background Postoperative sore throat (POST) is commonly reported by patients after endotracheal intubation. This study was conducted to compare the efficacy of intravenous lidocaine and dexamethasone in the prevention of such problem. Patients and methods We included a total of 394 cases who were ra...
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| Veröffentlicht in: | Research and Opinion in Anesthesia & Intensive Care 2022-10, Vol.9 (4), p.297-301 |
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| creator | Mohammed, Mohammed El Said Rashad, Ali |
| description | Background Postoperative sore throat (POST) is commonly reported by patients after endotracheal intubation. This study was conducted to compare the efficacy of intravenous lidocaine and dexamethasone in the prevention of such problem.
Patients and methods We included a total of 394 cases who were randomly divided using the closed-envelope method into two groups: group D that included 197 cases who received intravenous dexamethasone (8 mg), and group L that included the remaining 197 cases who received intravenous lidocaine (1.5 mg/kg). Both the incidence and risk factors for POST were assessed.
Results Sore throat was reported by 115 (58.4%) cases in group L, whereas it was reported by 82 (41.6%) cases of cases in the other group. There was a marked reduction of sore-throat sensation in group D (P |
| doi_str_mv | 10.4103/roaic.roaic_74_21 |
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Patients and methods We included a total of 394 cases who were randomly divided using the closed-envelope method into two groups: group D that included 197 cases who received intravenous dexamethasone (8 mg), and group L that included the remaining 197 cases who received intravenous lidocaine (1.5 mg/kg). Both the incidence and risk factors for POST were assessed.
Results Sore throat was reported by 115 (58.4%) cases in group L, whereas it was reported by 82 (41.6%) cases of cases in the other group. There was a marked reduction of sore-throat sensation in group D (P<0.001). Logistic regression revealed that the presence of blood on suction was a significant risk factor for developing sore throat after intubation.
Conclusion Intravenous administration of dexamethasone appears to be more promising than lidocaine in decreasing the incidence of POST.</description><identifier>ISSN: 2356-9115</identifier><identifier>EISSN: 2356-9123</identifier><identifier>DOI: 10.4103/roaic.roaic_74_21</identifier><language>eng</language><publisher>Mumbai: Wolters Kluwer India Pvt. Ltd</publisher><subject>Anesthesia ; Dexamethasone ; Intubation ; Lidocaine ; Medical research ; Medicine, Experimental ; Pain management ; Pharyngitis ; Postoperative period ; Risk factors ; Steroids</subject><ispartof>Research and Opinion in Anesthesia & Intensive Care, 2022-10, Vol.9 (4), p.297-301</ispartof><rights>COPYRIGHT 2022 Medknow Publications and Media Pvt. Ltd.</rights><rights>2022. This article is published under (http://creativecommons.org/licenses/by-nc-sa/3.0/) (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c228n-e5c9d2fa529aba720dede8d24e5db2b2e4a762418dd10900814f3d4a11a27ed53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,782,786,27467,27933,27934</link.rule.ids></links><search><creatorcontrib>Mohammed, Mohammed</creatorcontrib><creatorcontrib>El Said Rashad, Ali</creatorcontrib><title>Lidocaine versus dexamethasone for reduction of sore throat after general anesthesia: a comparative study</title><title>Research and Opinion in Anesthesia & Intensive Care</title><description>Background Postoperative sore throat (POST) is commonly reported by patients after endotracheal intubation. This study was conducted to compare the efficacy of intravenous lidocaine and dexamethasone in the prevention of such problem.
Patients and methods We included a total of 394 cases who were randomly divided using the closed-envelope method into two groups: group D that included 197 cases who received intravenous dexamethasone (8 mg), and group L that included the remaining 197 cases who received intravenous lidocaine (1.5 mg/kg). Both the incidence and risk factors for POST were assessed.
Results Sore throat was reported by 115 (58.4%) cases in group L, whereas it was reported by 82 (41.6%) cases of cases in the other group. There was a marked reduction of sore-throat sensation in group D (P<0.001). Logistic regression revealed that the presence of blood on suction was a significant risk factor for developing sore throat after intubation.
Conclusion Intravenous administration of dexamethasone appears to be more promising than lidocaine in decreasing the incidence of POST.</description><subject>Anesthesia</subject><subject>Dexamethasone</subject><subject>Intubation</subject><subject>Lidocaine</subject><subject>Medical research</subject><subject>Medicine, Experimental</subject><subject>Pain management</subject><subject>Pharyngitis</subject><subject>Postoperative period</subject><subject>Risk factors</subject><subject>Steroids</subject><issn>2356-9115</issn><issn>2356-9123</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNp1kctqHDEQRZsQQ4zjD8hOEMhuxlJJ_crODHkYBrKJ16JGKrkVd7cmktoT_73lTB42JAikorinStxbVW8EXyvB5UUM6M36561bpUG8qE5B1s2qFyBf_qlF_ao6T8nvOEipmg7q08pvvQ0G_UzsjmJaErP0AyfKA6ZQmi5EFskuJvsws-BYCpFYHsqyzNBliuyGZoo4Mpwp5YGSx_cMmQnTHiNmf0cs5cXev65OHI6Jzn-9Z9X1xw9fN59X2y-frjaX25UB6OYV1aa34LCGHnfYArdkqbOgqLY72AEpbBtQorNW8J7zTignrUIhEFqytTyr3h7n7mP4vpQv6W9hiXNZqaFtOG_6Xoq_qhscSfvZhRzRTD4ZfdlK4E0ruSqq9T9U5ViavCn-OF_6z4B3T4CBcMxDCuPy6F56LhRHoYkhpUhO76OfMN5rwfVjqPoY55NQC7M5MocwFuPT7bgcKOqJ7O0cDv8HNfSt_p2zfACXka_o</recordid><startdate>20221001</startdate><enddate>20221001</enddate><creator>Mohammed, Mohammed</creator><creator>El Said Rashad, Ali</creator><general>Wolters Kluwer India Pvt. Ltd</general><general>Medknow Publications and Media Pvt. Ltd</general><general>Medknow Publications & Media Pvt. Ltd</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope></search><sort><creationdate>20221001</creationdate><title>Lidocaine versus dexamethasone for reduction of sore throat after general anesthesia: a comparative study</title><author>Mohammed, Mohammed ; El Said Rashad, Ali</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c228n-e5c9d2fa529aba720dede8d24e5db2b2e4a762418dd10900814f3d4a11a27ed53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Anesthesia</topic><topic>Dexamethasone</topic><topic>Intubation</topic><topic>Lidocaine</topic><topic>Medical research</topic><topic>Medicine, Experimental</topic><topic>Pain management</topic><topic>Pharyngitis</topic><topic>Postoperative period</topic><topic>Risk factors</topic><topic>Steroids</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mohammed, Mohammed</creatorcontrib><creatorcontrib>El Said Rashad, Ali</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Health and Medical</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><jtitle>Research and Opinion in Anesthesia & Intensive Care</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mohammed, Mohammed</au><au>El Said Rashad, Ali</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lidocaine versus dexamethasone for reduction of sore throat after general anesthesia: a comparative study</atitle><jtitle>Research and Opinion in Anesthesia & Intensive Care</jtitle><date>2022-10-01</date><risdate>2022</risdate><volume>9</volume><issue>4</issue><spage>297</spage><epage>301</epage><pages>297-301</pages><issn>2356-9115</issn><eissn>2356-9123</eissn><abstract>Background Postoperative sore throat (POST) is commonly reported by patients after endotracheal intubation. This study was conducted to compare the efficacy of intravenous lidocaine and dexamethasone in the prevention of such problem.
Patients and methods We included a total of 394 cases who were randomly divided using the closed-envelope method into two groups: group D that included 197 cases who received intravenous dexamethasone (8 mg), and group L that included the remaining 197 cases who received intravenous lidocaine (1.5 mg/kg). Both the incidence and risk factors for POST were assessed.
Results Sore throat was reported by 115 (58.4%) cases in group L, whereas it was reported by 82 (41.6%) cases of cases in the other group. There was a marked reduction of sore-throat sensation in group D (P<0.001). Logistic regression revealed that the presence of blood on suction was a significant risk factor for developing sore throat after intubation.
Conclusion Intravenous administration of dexamethasone appears to be more promising than lidocaine in decreasing the incidence of POST.</abstract><cop>Mumbai</cop><pub>Wolters Kluwer India Pvt. Ltd</pub><doi>10.4103/roaic.roaic_74_21</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Anesthesia Dexamethasone Intubation Lidocaine Medical research Medicine, Experimental Pain management Pharyngitis Postoperative period Risk factors Steroids |
| title | Lidocaine versus dexamethasone for reduction of sore throat after general anesthesia: a comparative study |
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