Analysis of Human Leukocyte Antigen DR Alleles, Immune-Related Adverse Events, and Survival Associated With Immune Checkpoint Inhibitor Use Among Patients With Advanced Malignant Melanoma

Treatment with immune checkpoint inhibitors (ICIs) has increased survival in patients with advanced malignant melanoma but can be associated with a wide range of immune-related adverse events (irAEs). The role of human leukocyte antigen (HLA)-DR alleles in conferring irAE risk has not been well stud...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	JAMA network open 2022-12, Vol.5 (12), p.e2246400
Hauptverfasser:	Akturk, Halis Kaan, Couts, Kasey L, Baschal, Erin E, Karakus, Kagan E, Van Gulick, Robert J, Turner, Jacqueline A, Pyle, Laura, Robinson, William A, Michels, Aaron W
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Antigens Antineoplastic Agents, Immunological - adverse effects Case-Control Studies Female HLA-DR Antigens - genetics Humans Immune Checkpoint Inhibitors - adverse effects Male Melanoma Melanoma - drug therapy Melanoma - genetics Melanoma, Cutaneous Malignant Middle Aged Response rates Skin cancer
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!