A Phytochemical Analysis, Antioxidant and Antidiabetic activities in vitro of Pergularia tomentosa L. leaves
The present investigation is aimed at screening the bioactive compounds present in the leaves of Pergularia tomentosa L. an important ethnomedicinal plant. The qualitative analysis for the present phytochemicals was performed using MeOH/H2O extracts. Phytochemical analysis showed the existence of so...
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| Veröffentlicht in: | Research journal of pharmacy and technology 2022-09, Vol.15 (9), p.3941-3946 |
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| container_title | Research journal of pharmacy and technology |
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| creator | Tatou, Touahria Zehour, Rahmani Zineb, Rahmani Asma, Abid Mahdi, Belguidoum Cheyma, Bensaci |
| description | The present investigation is aimed at screening the bioactive compounds present in the leaves of Pergularia tomentosa L. an important ethnomedicinal plant. The qualitative analysis for the present phytochemicals was performed using MeOH/H2O extracts. Phytochemical analysis showed the existence of some primary and secondary metabolites, phenolic, flavonoids, cardenolides, tannins, alkaloids, quinones, terpenoids and glycoside; leaves contained the highest amounts of all these compounds. The highest total phenolic content and total tannins was observed in aqueous extract which is 2.59±0.49 mg GAE/g DW and 0.436±0.00 mg CE/g DW respectively. In addition, the highest total flavonoid content was observed in butanol extract which is 0.486±0.01mg QE/g DW. Reducing power assay and DPPH were employed to measure antioxidant activity in vitro, extracts were the most powerful antioxidants for the two-assay in vitro system. In addition, we investigated in vitro anti-diabetic activity of different extracts. The dichloromethane extract of Pergularia tomentosa L. showed strong antidiabetic antidiabetic activity. |
| doi_str_mv | 10.52711/0974-360X.2022.00660 |
| format | Article |
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The qualitative analysis for the present phytochemicals was performed using MeOH/H2O extracts. Phytochemical analysis showed the existence of some primary and secondary metabolites, phenolic, flavonoids, cardenolides, tannins, alkaloids, quinones, terpenoids and glycoside; leaves contained the highest amounts of all these compounds. The highest total phenolic content and total tannins was observed in aqueous extract which is 2.59±0.49 mg GAE/g DW and 0.436±0.00 mg CE/g DW respectively. In addition, the highest total flavonoid content was observed in butanol extract which is 0.486±0.01mg QE/g DW. Reducing power assay and DPPH were employed to measure antioxidant activity in vitro, extracts were the most powerful antioxidants for the two-assay in vitro system. In addition, we investigated in vitro anti-diabetic activity of different extracts. The dichloromethane extract of Pergularia tomentosa L. showed strong antidiabetic antidiabetic activity.</description><identifier>ISSN: 0974-3618</identifier><identifier>EISSN: 0974-360X</identifier><identifier>EISSN: 0974-306X</identifier><identifier>DOI: 10.52711/0974-360X.2022.00660</identifier><language>eng</language><publisher>Raipur: A&V Publications</publisher><subject>Antidiabetics ; Antioxidants ; Diabetes ; Flavonoids ; Free radicals ; Herbal medicine ; Hydrochloric acid ; Metabolism ; Metabolites ; Phytochemicals ; Polyphenols ; Power ; Reagents ; Sulfur</subject><ispartof>Research journal of pharmacy and technology, 2022-09, Vol.15 (9), p.3941-3946</ispartof><rights>Copyright A&V Publications Sep 2022</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c196t-337921b17bc4783e8084eeae9ccc25381e4736d74b5dbc1fec5c2b546b50ac4d3</citedby><cites>FETCH-LOGICAL-c196t-337921b17bc4783e8084eeae9ccc25381e4736d74b5dbc1fec5c2b546b50ac4d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids></links><search><creatorcontrib>Tatou, Touahria</creatorcontrib><creatorcontrib>Zehour, Rahmani</creatorcontrib><creatorcontrib>Zineb, Rahmani</creatorcontrib><creatorcontrib>Asma, Abid</creatorcontrib><creatorcontrib>Mahdi, Belguidoum</creatorcontrib><creatorcontrib>Cheyma, Bensaci</creatorcontrib><title>A Phytochemical Analysis, Antioxidant and Antidiabetic activities in vitro of Pergularia tomentosa L. leaves</title><title>Research journal of pharmacy and technology</title><description>The present investigation is aimed at screening the bioactive compounds present in the leaves of Pergularia tomentosa L. an important ethnomedicinal plant. 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The dichloromethane extract of Pergularia tomentosa L. showed strong antidiabetic antidiabetic activity.</description><subject>Antidiabetics</subject><subject>Antioxidants</subject><subject>Diabetes</subject><subject>Flavonoids</subject><subject>Free radicals</subject><subject>Herbal medicine</subject><subject>Hydrochloric acid</subject><subject>Metabolism</subject><subject>Metabolites</subject><subject>Phytochemicals</subject><subject>Polyphenols</subject><subject>Power</subject><subject>Reagents</subject><subject>Sulfur</subject><issn>0974-3618</issn><issn>0974-360X</issn><issn>0974-306X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNo9kFtLAzEQhYMoWLQ_QQj4atfcs_tYijco2AcF30I2O2tTtpuapMX-e7etdF7mnOEwcD6E7igpJNOUPpJKiwlX5KtghLGCEKXIBRqdz5dnTctrNE5pRYZRpWSiHKFuihfLfQ5uCWvvbIenve32yaeHQWUffn1j-4xt3xx9420N2TtsXfY7nz0k7Hs8qBhwaPEC4ve2s9FbnMMa-hySxfMCd2B3kG7RVWu7BOP_fYM-n58-Zq-T-fvL22w6nzhaqTzhXFeM1lTXTuiSQ0lKAWChcs4xyUsKQnPVaFHLpna0BScdq6VQtSTWiYbfoPvT300MP1tI2azCNg7FkmFaDs15RdWQkqeUiyGlCK3ZRL-2cW8oMUe25gDOHCCaA1tzZMv_APGzbWg</recordid><startdate>20220901</startdate><enddate>20220901</enddate><creator>Tatou, Touahria</creator><creator>Zehour, Rahmani</creator><creator>Zineb, Rahmani</creator><creator>Asma, Abid</creator><creator>Mahdi, Belguidoum</creator><creator>Cheyma, Bensaci</creator><general>A&V Publications</general><scope>AAYXX</scope><scope>CITATION</scope><scope>04Q</scope><scope>04S</scope><scope>04W</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope></search><sort><creationdate>20220901</creationdate><title>A Phytochemical Analysis, Antioxidant and Antidiabetic activities in vitro of Pergularia tomentosa L. leaves</title><author>Tatou, Touahria ; 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The qualitative analysis for the present phytochemicals was performed using MeOH/H2O extracts. Phytochemical analysis showed the existence of some primary and secondary metabolites, phenolic, flavonoids, cardenolides, tannins, alkaloids, quinones, terpenoids and glycoside; leaves contained the highest amounts of all these compounds. The highest total phenolic content and total tannins was observed in aqueous extract which is 2.59±0.49 mg GAE/g DW and 0.436±0.00 mg CE/g DW respectively. In addition, the highest total flavonoid content was observed in butanol extract which is 0.486±0.01mg QE/g DW. Reducing power assay and DPPH were employed to measure antioxidant activity in vitro, extracts were the most powerful antioxidants for the two-assay in vitro system. In addition, we investigated in vitro anti-diabetic activity of different extracts. The dichloromethane extract of Pergularia tomentosa L. showed strong antidiabetic antidiabetic activity.</abstract><cop>Raipur</cop><pub>A&V Publications</pub><doi>10.52711/0974-360X.2022.00660</doi><tpages>6</tpages></addata></record> |
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| subjects | Antidiabetics Antioxidants Diabetes Flavonoids Free radicals Herbal medicine Hydrochloric acid Metabolism Metabolites Phytochemicals Polyphenols Power Reagents Sulfur |
| title | A Phytochemical Analysis, Antioxidant and Antidiabetic activities in vitro of Pergularia tomentosa L. leaves |
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