Effect of Afghan Withania coagulans L. and Ferula assa-foetida L. extracts combination on Blood Glucose Level of Diabetic rats
Afghan medicinal plants are famous for their nutritional and pharmacological activities. Afghan people are using medicinal herbs alone or in combination for treatment of diseases. This study is designed to evaluate the effect of two Afghan medicinal plants, Withania Coagulans L. and Ferula Assa-foet...
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| Veröffentlicht in: | Research journal of pharmacy and technology 2022-10, Vol.15 (10), p.4715-4719 |
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| creator | Alami, Kawsar Yousof Mousavi, Sayed |
| description | Afghan medicinal plants are famous for their nutritional and pharmacological activities. Afghan people are using medicinal herbs alone or in combination for treatment of diseases. This study is designed to evaluate the effect of two Afghan medicinal plants, Withania Coagulans L. and Ferula Assa-foetida L. extracts combination on blood glucose level of diabetic rats. Rats became diabetic by a single dose administration of streptozotocin and treated with Withania Coagulans and Ferula Assa-foetida extracts either alone or in combination for 21 days. The initial and final body weight and fasting blood glucose of rats were determined. Results showed that treatment with both Withania Coagulans and Ferula Assa-foetida extracts over 21 days period leads to a considerable reduction in blood glucose level of diabetic rats. In addition, their combinations in different proportions also showed a notable anti-hyperglycemic effect on diabetic rats (P < 0.0001). The Withania Coagulans and Ferula Assa-foetida combinations formula effect was even better than each individual plants. As a result, combinations of Withania Coagulans and Ferula Assa-foetida extracts have a synergic effect on blood glucose level of diabetic rats. |
| doi_str_mv | 10.52711/0974-360X.2022.00792 |
| format | Article |
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Afghan people are using medicinal herbs alone or in combination for treatment of diseases. This study is designed to evaluate the effect of two Afghan medicinal plants, Withania Coagulans L. and Ferula Assa-foetida L. extracts combination on blood glucose level of diabetic rats. Rats became diabetic by a single dose administration of streptozotocin and treated with Withania Coagulans and Ferula Assa-foetida extracts either alone or in combination for 21 days. The initial and final body weight and fasting blood glucose of rats were determined. Results showed that treatment with both Withania Coagulans and Ferula Assa-foetida extracts over 21 days period leads to a considerable reduction in blood glucose level of diabetic rats. In addition, their combinations in different proportions also showed a notable anti-hyperglycemic effect on diabetic rats (P < 0.0001). The Withania Coagulans and Ferula Assa-foetida combinations formula effect was even better than each individual plants. As a result, combinations of Withania Coagulans and Ferula Assa-foetida extracts have a synergic effect on blood glucose level of diabetic rats.</description><identifier>ISSN: 0974-3618</identifier><identifier>EISSN: 0974-360X</identifier><identifier>EISSN: 0974-306X</identifier><identifier>DOI: 10.52711/0974-360X.2022.00792</identifier><language>eng</language><publisher>Raipur: A&V Publications</publisher><subject>Diabetes ; Fasting ; Flowers & plants ; Glucose ; Herbal medicine ; Hyperglycemia ; Laboratory animals</subject><ispartof>Research journal of pharmacy and technology, 2022-10, Vol.15 (10), p.4715-4719</ispartof><rights>Copyright A&V Publications Oct 2022</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c144t-b0fcaea2dad73a979b71fe6d4343d88726e1e2ce7afc16188e64a5e1f8f14ba13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27922,27923</link.rule.ids></links><search><creatorcontrib>Alami, Kawsar</creatorcontrib><creatorcontrib>Yousof Mousavi, Sayed</creatorcontrib><title>Effect of Afghan Withania coagulans L. and Ferula assa-foetida L. extracts combination on Blood Glucose Level of Diabetic rats</title><title>Research journal of pharmacy and technology</title><description>Afghan medicinal plants are famous for their nutritional and pharmacological activities. Afghan people are using medicinal herbs alone or in combination for treatment of diseases. This study is designed to evaluate the effect of two Afghan medicinal plants, Withania Coagulans L. and Ferula Assa-foetida L. extracts combination on blood glucose level of diabetic rats. Rats became diabetic by a single dose administration of streptozotocin and treated with Withania Coagulans and Ferula Assa-foetida extracts either alone or in combination for 21 days. The initial and final body weight and fasting blood glucose of rats were determined. Results showed that treatment with both Withania Coagulans and Ferula Assa-foetida extracts over 21 days period leads to a considerable reduction in blood glucose level of diabetic rats. In addition, their combinations in different proportions also showed a notable anti-hyperglycemic effect on diabetic rats (P < 0.0001). The Withania Coagulans and Ferula Assa-foetida combinations formula effect was even better than each individual plants. As a result, combinations of Withania Coagulans and Ferula Assa-foetida extracts have a synergic effect on blood glucose level of diabetic rats.</description><subject>Diabetes</subject><subject>Fasting</subject><subject>Flowers & plants</subject><subject>Glucose</subject><subject>Herbal medicine</subject><subject>Hyperglycemia</subject><subject>Laboratory animals</subject><issn>0974-3618</issn><issn>0974-360X</issn><issn>0974-306X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNo9kF9LwzAQwIsoOOY-ghDwuTNJ06Z9nHObwsAXRd_CNb3Mjq6ZSSb64mc33cTj4P7fcb8kuWZ0mnPJ2C2tpEizgr5NOeV8Sqms-Fky-k-f__usvEwm3m9plKLMuShHyc_CGNSBWENmZvMOPXltQzQtEG1hc-ig92Q9JdA3ZIkuxgS8h9RYDG0DQwm_ggMdfBzY1W0PobU9iXrXWduQVXfQ1iNZ4yd2w5n7Fuo4q4mD4K-SCwOdx8mfHScvy8Xz_CFdP60e57N1qpkQIa2p0YDAG2hkBpWsaskMFo3IRNaUpeQFMuQaJRjN4p8lFgJyZKY0TNTAsnFyc9q7d_bjgD6orT24Pp5UXOZlVglBaezKT13aWe8dGrV37Q7ct2JUHWmrAaUasKqBtjrSzn4B5LxzFA</recordid><startdate>20221001</startdate><enddate>20221001</enddate><creator>Alami, Kawsar</creator><creator>Yousof Mousavi, Sayed</creator><general>A&V Publications</general><scope>AAYXX</scope><scope>CITATION</scope><scope>04Q</scope><scope>04S</scope><scope>04W</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope></search><sort><creationdate>20221001</creationdate><title>Effect of Afghan Withania coagulans L. and Ferula assa-foetida L. extracts combination on Blood Glucose Level of Diabetic rats</title><author>Alami, Kawsar ; Yousof Mousavi, Sayed</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c144t-b0fcaea2dad73a979b71fe6d4343d88726e1e2ce7afc16188e64a5e1f8f14ba13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Diabetes</topic><topic>Fasting</topic><topic>Flowers & plants</topic><topic>Glucose</topic><topic>Herbal medicine</topic><topic>Hyperglycemia</topic><topic>Laboratory animals</topic><toplevel>online_resources</toplevel><creatorcontrib>Alami, Kawsar</creatorcontrib><creatorcontrib>Yousof Mousavi, Sayed</creatorcontrib><collection>CrossRef</collection><collection>India Database</collection><collection>India Database: Business</collection><collection>India Database: Science & Technology</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><jtitle>Research journal of pharmacy and technology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Alami, Kawsar</au><au>Yousof Mousavi, Sayed</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of Afghan Withania coagulans L. and Ferula assa-foetida L. extracts combination on Blood Glucose Level of Diabetic rats</atitle><jtitle>Research journal of pharmacy and technology</jtitle><date>2022-10-01</date><risdate>2022</risdate><volume>15</volume><issue>10</issue><spage>4715</spage><epage>4719</epage><pages>4715-4719</pages><issn>0974-3618</issn><eissn>0974-360X</eissn><eissn>0974-306X</eissn><abstract>Afghan medicinal plants are famous for their nutritional and pharmacological activities. Afghan people are using medicinal herbs alone or in combination for treatment of diseases. This study is designed to evaluate the effect of two Afghan medicinal plants, Withania Coagulans L. and Ferula Assa-foetida L. extracts combination on blood glucose level of diabetic rats. Rats became diabetic by a single dose administration of streptozotocin and treated with Withania Coagulans and Ferula Assa-foetida extracts either alone or in combination for 21 days. The initial and final body weight and fasting blood glucose of rats were determined. Results showed that treatment with both Withania Coagulans and Ferula Assa-foetida extracts over 21 days period leads to a considerable reduction in blood glucose level of diabetic rats. In addition, their combinations in different proportions also showed a notable anti-hyperglycemic effect on diabetic rats (P < 0.0001). The Withania Coagulans and Ferula Assa-foetida combinations formula effect was even better than each individual plants. As a result, combinations of Withania Coagulans and Ferula Assa-foetida extracts have a synergic effect on blood glucose level of diabetic rats.</abstract><cop>Raipur</cop><pub>A&V Publications</pub><doi>10.52711/0974-360X.2022.00792</doi><tpages>5</tpages></addata></record> |
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| subjects | Diabetes Fasting Flowers & plants Glucose Herbal medicine Hyperglycemia Laboratory animals |
| title | Effect of Afghan Withania coagulans L. and Ferula assa-foetida L. extracts combination on Blood Glucose Level of Diabetic rats |
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