Aortic valve calcium score in prediction of post-TAVI complications in an Egyptian cohort

Background Severe symptomatic aortic stenosis is a common disorder in the elderly and is associated with high morbidity and mortality rate. Traditionally, surgical aortic valve replacement has been considered the most effective treatment for advanced disease. Transcatheter aortic valve implantation...

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Veröffentlicht in:Egyptian Journal of Radiology and Nuclear Medicine 2022-12, Vol.53 (1), p.260-8, Article 260
Hauptverfasser: Salem, Mohammed Ali, Ismail, Ahmed Shehata, Donkol, Ragab Hani, Reyad, Mohamed Adam, Ramadan, Ahmed Mohammed
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container_issue 1
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creator Salem, Mohammed Ali
Ismail, Ahmed Shehata
Donkol, Ragab Hani
Reyad, Mohamed Adam
Ramadan, Ahmed Mohammed
description Background Severe symptomatic aortic stenosis is a common disorder in the elderly and is associated with high morbidity and mortality rate. Traditionally, surgical aortic valve replacement has been considered the most effective treatment for advanced disease. Transcatheter aortic valve implantation (TAVI) has been established as a valuable alternative treatment option for inoperable and high-risk patients with symptomatic severe aortic stenosis. Pre-procedure ECG-gated CT aortography study is important in planning the procedure. The aim of the study was to correlate the aortic valve calcium score with the post-TAVI complications. Results Thirty patients who were candidates for TAVI procedure were enrolled for ECG-gated CT aortic valve calcium score and CT aortography. The calcium score was calculated. The patients were followed up both clinically and by echocardiography every 3 months for 1 year. Those who developed complications were enrolled for another CT study. Fourteen out of 30 patients (46.7%) presented with post-TAVI complications [9 cases (30%) presented with paravalvular leak (PVL) and 5 cases (16.7%) presented with major adverse cardiac events (MACE), while 16 cases (53.3%) had no complications]. There was a strong correlation between the calcium score and post-procedure complications. Conclusions The degree of aortic valve calcification can be considered as a predictor of post-TAVI complications: PVL and MACE.
doi_str_mv 10.1186/s43055-022-00946-2
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Traditionally, surgical aortic valve replacement has been considered the most effective treatment for advanced disease. Transcatheter aortic valve implantation (TAVI) has been established as a valuable alternative treatment option for inoperable and high-risk patients with symptomatic severe aortic stenosis. Pre-procedure ECG-gated CT aortography study is important in planning the procedure. The aim of the study was to correlate the aortic valve calcium score with the post-TAVI complications. Results Thirty patients who were candidates for TAVI procedure were enrolled for ECG-gated CT aortic valve calcium score and CT aortography. The calcium score was calculated. The patients were followed up both clinically and by echocardiography every 3 months for 1 year. Those who developed complications were enrolled for another CT study. Fourteen out of 30 patients (46.7%) presented with post-TAVI complications [9 cases (30%) presented with paravalvular leak (PVL) and 5 cases (16.7%) presented with major adverse cardiac events (MACE), while 16 cases (53.3%) had no complications]. There was a strong correlation between the calcium score and post-procedure complications. Conclusions The degree of aortic valve calcification can be considered as a predictor of post-TAVI complications: PVL and MACE.</description><identifier>ISSN: 2090-4762</identifier><identifier>ISSN: 0378-603X</identifier><identifier>EISSN: 2090-4762</identifier><identifier>DOI: 10.1186/s43055-022-00946-2</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Angina pectoris ; Aortic stenosis ; Aortic valve calcium score ; Aortic valve stenosis ; Calcification ; Cardiovascular disease ; Care and treatment ; Complications ; Coronary vessels ; Diabetes ; Electrocardiogram ; Electrocardiography ; Heart failure ; Heart rate ; Hyperlipidemia ; Hypertension ; Imaging ; Medical research ; Medicine ; Medicine &amp; Public Health ; Medicine, Experimental ; Mortality ; Nuclear Medicine ; Patients ; Pulmonary arteries ; Radiology ; Risk factors ; Surgery ; Taiwan ; Transcatheter aortic valve implantation (TAVI) ; Work stations</subject><ispartof>Egyptian Journal of Radiology and Nuclear Medicine, 2022-12, Vol.53 (1), p.260-8, Article 260</ispartof><rights>The Author(s) 2022</rights><rights>COPYRIGHT 2022 Springer</rights><rights>The Author(s) 2022. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c496t-1388a6c785e6bdb5b70d4664562fbd4c42f59d3a75523b245c5dfb5cc095903a3</citedby><cites>FETCH-LOGICAL-c496t-1388a6c785e6bdb5b70d4664562fbd4c42f59d3a75523b245c5dfb5cc095903a3</cites><orcidid>0000-0002-0350-3039</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,864,27923,27924</link.rule.ids></links><search><creatorcontrib>Salem, Mohammed Ali</creatorcontrib><creatorcontrib>Ismail, Ahmed Shehata</creatorcontrib><creatorcontrib>Donkol, Ragab Hani</creatorcontrib><creatorcontrib>Reyad, Mohamed Adam</creatorcontrib><creatorcontrib>Ramadan, Ahmed Mohammed</creatorcontrib><title>Aortic valve calcium score in prediction of post-TAVI complications in an Egyptian cohort</title><title>Egyptian Journal of Radiology and Nuclear Medicine</title><addtitle>Egypt J Radiol Nucl Med</addtitle><description>Background Severe symptomatic aortic stenosis is a common disorder in the elderly and is associated with high morbidity and mortality rate. Traditionally, surgical aortic valve replacement has been considered the most effective treatment for advanced disease. Transcatheter aortic valve implantation (TAVI) has been established as a valuable alternative treatment option for inoperable and high-risk patients with symptomatic severe aortic stenosis. Pre-procedure ECG-gated CT aortography study is important in planning the procedure. The aim of the study was to correlate the aortic valve calcium score with the post-TAVI complications. Results Thirty patients who were candidates for TAVI procedure were enrolled for ECG-gated CT aortic valve calcium score and CT aortography. The calcium score was calculated. The patients were followed up both clinically and by echocardiography every 3 months for 1 year. Those who developed complications were enrolled for another CT study. Fourteen out of 30 patients (46.7%) presented with post-TAVI complications [9 cases (30%) presented with paravalvular leak (PVL) and 5 cases (16.7%) presented with major adverse cardiac events (MACE), while 16 cases (53.3%) had no complications]. There was a strong correlation between the calcium score and post-procedure complications. Conclusions The degree of aortic valve calcification can be considered as a predictor of post-TAVI complications: PVL and MACE.</description><subject>Angina pectoris</subject><subject>Aortic stenosis</subject><subject>Aortic valve calcium score</subject><subject>Aortic valve stenosis</subject><subject>Calcification</subject><subject>Cardiovascular disease</subject><subject>Care and treatment</subject><subject>Complications</subject><subject>Coronary vessels</subject><subject>Diabetes</subject><subject>Electrocardiogram</subject><subject>Electrocardiography</subject><subject>Heart failure</subject><subject>Heart rate</subject><subject>Hyperlipidemia</subject><subject>Hypertension</subject><subject>Imaging</subject><subject>Medical research</subject><subject>Medicine</subject><subject>Medicine &amp; Public Health</subject><subject>Medicine, Experimental</subject><subject>Mortality</subject><subject>Nuclear Medicine</subject><subject>Patients</subject><subject>Pulmonary arteries</subject><subject>Radiology</subject><subject>Risk factors</subject><subject>Surgery</subject><subject>Taiwan</subject><subject>Transcatheter aortic valve implantation (TAVI)</subject><subject>Work stations</subject><issn>2090-4762</issn><issn>0378-603X</issn><issn>2090-4762</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>DOA</sourceid><recordid>eNp9kU-LFDEQxRtRcFn3C3gKeO61ks6fznFYVh1Y8LIKnkK6kowZujtt0rOw397MtrgKYnJIUXnvRxWvad5SuKa0l-8L70CIFhhrATSXLXvRXDDQ0HIl2cs_6tfNVSlHqIcDUMkvmm-7lNeI5MGOD56gHTGeJlIwZU_iTJbsXcQ1ppmkQJZU1vZ-93VPME3LGNGef8pZaGdye3hc1lgLTN8r9E3zKtix-Ktf72Xz5cPt_c2n9u7zx_3N7q5FruXa0q7vrUTVCy8HN4hBgeNSciFZGBxHzoLQrrNKCNYNjAsULgwCEbTQ0NnustlvXJfs0Sw5TjY_mmSjeWqkfDD2vOLoDXc9oBaSYvBcY9B8cIC0gilQB6qy3m2sJacfJ19Wc0ynPNfxDVNCsU5SQZ9VB1uhcQ5pzRanWNDsVEUJ3StZVdf_UNXr_BQxzT7E2v_LwDYD5lRK9uH3MhTMOWizBW1q0OYpaMOqqdtMpYrng8_PE__H9RP8L6gj</recordid><startdate>20221201</startdate><enddate>20221201</enddate><creator>Salem, Mohammed Ali</creator><creator>Ismail, Ahmed Shehata</creator><creator>Donkol, Ragab Hani</creator><creator>Reyad, Mohamed Adam</creator><creator>Ramadan, Ahmed Mohammed</creator><general>Springer Berlin Heidelberg</general><general>Springer</general><general>Springer Nature B.V</general><general>SpringerOpen</general><scope>C6C</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-0350-3039</orcidid></search><sort><creationdate>20221201</creationdate><title>Aortic valve calcium score in prediction of post-TAVI complications in an Egyptian cohort</title><author>Salem, Mohammed Ali ; Ismail, Ahmed Shehata ; Donkol, Ragab Hani ; Reyad, Mohamed Adam ; Ramadan, Ahmed Mohammed</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c496t-1388a6c785e6bdb5b70d4664562fbd4c42f59d3a75523b245c5dfb5cc095903a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Angina pectoris</topic><topic>Aortic stenosis</topic><topic>Aortic valve calcium score</topic><topic>Aortic valve stenosis</topic><topic>Calcification</topic><topic>Cardiovascular disease</topic><topic>Care and treatment</topic><topic>Complications</topic><topic>Coronary vessels</topic><topic>Diabetes</topic><topic>Electrocardiogram</topic><topic>Electrocardiography</topic><topic>Heart failure</topic><topic>Heart rate</topic><topic>Hyperlipidemia</topic><topic>Hypertension</topic><topic>Imaging</topic><topic>Medical research</topic><topic>Medicine</topic><topic>Medicine &amp; Public Health</topic><topic>Medicine, Experimental</topic><topic>Mortality</topic><topic>Nuclear Medicine</topic><topic>Patients</topic><topic>Pulmonary arteries</topic><topic>Radiology</topic><topic>Risk factors</topic><topic>Surgery</topic><topic>Taiwan</topic><topic>Transcatheter aortic valve implantation (TAVI)</topic><topic>Work stations</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Salem, Mohammed Ali</creatorcontrib><creatorcontrib>Ismail, Ahmed Shehata</creatorcontrib><creatorcontrib>Donkol, Ragab Hani</creatorcontrib><creatorcontrib>Reyad, Mohamed Adam</creatorcontrib><creatorcontrib>Ramadan, Ahmed Mohammed</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health &amp; 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Traditionally, surgical aortic valve replacement has been considered the most effective treatment for advanced disease. Transcatheter aortic valve implantation (TAVI) has been established as a valuable alternative treatment option for inoperable and high-risk patients with symptomatic severe aortic stenosis. Pre-procedure ECG-gated CT aortography study is important in planning the procedure. The aim of the study was to correlate the aortic valve calcium score with the post-TAVI complications. Results Thirty patients who were candidates for TAVI procedure were enrolled for ECG-gated CT aortic valve calcium score and CT aortography. The calcium score was calculated. The patients were followed up both clinically and by echocardiography every 3 months for 1 year. Those who developed complications were enrolled for another CT study. Fourteen out of 30 patients (46.7%) presented with post-TAVI complications [9 cases (30%) presented with paravalvular leak (PVL) and 5 cases (16.7%) presented with major adverse cardiac events (MACE), while 16 cases (53.3%) had no complications]. There was a strong correlation between the calcium score and post-procedure complications. Conclusions The degree of aortic valve calcification can be considered as a predictor of post-TAVI complications: PVL and MACE.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><doi>10.1186/s43055-022-00946-2</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0002-0350-3039</orcidid><oa>free_for_read</oa></addata></record>
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subjects Angina pectoris
Aortic stenosis
Aortic valve calcium score
Aortic valve stenosis
Calcification
Cardiovascular disease
Care and treatment
Complications
Coronary vessels
Diabetes
Electrocardiogram
Electrocardiography
Heart failure
Heart rate
Hyperlipidemia
Hypertension
Imaging
Medical research
Medicine
Medicine & Public Health
Medicine, Experimental
Mortality
Nuclear Medicine
Patients
Pulmonary arteries
Radiology
Risk factors
Surgery
Taiwan
Transcatheter aortic valve implantation (TAVI)
Work stations
title Aortic valve calcium score in prediction of post-TAVI complications in an Egyptian cohort
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