Silibinin-Loaded Nanostructured Lipid Carriers for Growth Inhibition of Cisplatin-Resistant Ovarian Cancer Cells

Cisplatin is the most often used chemotherapy in the treatment of ovarian cancer (OC), however long-term usage leads to drug resistance and treatment failure. Silibinin is a sparingly water-soluble natural compound with well-known anticancer effects. The use of lipid-based delivery systems is a pote...

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Veröffentlicht in:	Assay and drug development technologies 2022-12, Vol.20 (8), p.339-348
Hauptverfasser:	Jafari, Sevda, Bakhshaei, Atabak, Eskandani, Morteza, Molavi, Ommoleila
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticancer properties Cell Line, Tumor Chemotherapy Cisplatin Cocoa butter Drug Carriers Drug delivery Drug delivery systems Drug resistance Female Growth inhibition Humans Lipids Nanostructure Ovarian cancer Ovarian Neoplasms Silibinin Silybin Zeta potential
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