Virtual Lifestyle Intervention Tailored for Adults with Type 2 Diabetes: Effects by Baseline HbA1c
Background: Lifestyle interventions improve glycemic control in adults with type 2 diabetes (T2D) but are expensive and have limited accessibility. We recently demonstrated the efficacy of a virtual diabetes-tailored weight management program (WW, formerly Weight Watchers) on glycemic control in adu...
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| Veröffentlicht in: | Obesity (Silver Spring, Md.) Md.), 2022-11, Vol.30, p.36-37 |
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| container_title | Obesity (Silver Spring, Md.) |
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| creator | LaRose, Jessica Gokee Anton, Stephen Apolzan, John Beyl, Robbie Greenway, Frank Wickham, Edmond Lanoye, Autumn Harris, Melissa Martin, Corby Kaufman, Adam Foster, Gary Cardel, Michelle |
| description | Background: Lifestyle interventions improve glycemic control in adults with type 2 diabetes (T2D) but are expensive and have limited accessibility. We recently demonstrated the efficacy of a virtual diabetes-tailored weight management program (WW, formerly Weight Watchers) on glycemic control in adults with T2D. The goal of this work was to examine effects by HbA1c at trial entry. Methods: This was a prospective 24-week single arm, three-site clinical trial in adults (N=136) with T2D and a BMI between 27-50 kg/m2; 62% (n=84) had a baseline HbA1c between 7-8% and 38% (n=52) between 8-11%. Participants received a 24-wk intervention, which included the WW digital program tailored for people with T2D (virtual workshops + the WW App). Assessments occurred at 0, wk 12, and wk 24. Primary outcome was change in HbA1c at 24 wks (83% retention). Secondary outcomes were changes in weight and the Diabetes Distress Scale (DDS). In an intent-to-treat analysis, generalized linear effects models were used. Results: Participants were 56.8 ± 0.8 y, 80.2% female, 62.2% non-Hispanic White. Mean baseline values for participants 8% were: BMI=36.6+0.6 kg/m2 vs. 37.4+.8 kg/m2; HbA1c=7.4+0.1% vs. 8.95+1%; weight=99.7+1.9 kg vs. 103.5+2.4kg; total DDS score=2.1+0.1 vs. 2.7+1. HbA1c decreased for both groups over time ( |
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| fullrecord | <record><control><sourceid>proquest</sourceid><recordid>TN_cdi_proquest_journals_2754553732</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2754553732</sourcerecordid><originalsourceid>FETCH-proquest_journals_27545537323</originalsourceid><addsrcrecordid>eNqNjckKwjAURYMoOP7DA9dC2lir7uqEgssi7iRtXzASkppB6d_bhbh2dS6cC6dDBtGK0VnKVtfuby-jPhk696B0vqBJNCDFRVofuIKzFOh8oxBO2qN9ofbSaMi5VMZiBcJYyKqgvIO39HfImxohhp3kBXp0a9gLgWVriwY23KGSGuFYZFE5Jj3BlcPJlyMyPezz7XFWW_MMbfT2MMHqVt3iNJknCUtZzP57fQBjGkXy</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2754553732</pqid></control><display><type>article</type><title>Virtual Lifestyle Intervention Tailored for Adults with Type 2 Diabetes: Effects by Baseline HbA1c</title><source>Wiley Online Library - AutoHoldings Journals</source><source>Wiley Free Content</source><creator>LaRose, Jessica Gokee ; Anton, Stephen ; Apolzan, John ; Beyl, Robbie ; Greenway, Frank ; Wickham, Edmond ; Lanoye, Autumn ; Harris, Melissa ; Martin, Corby ; Kaufman, Adam ; Foster, Gary ; Cardel, Michelle</creator><creatorcontrib>LaRose, Jessica Gokee ; Anton, Stephen ; Apolzan, John ; Beyl, Robbie ; Greenway, Frank ; Wickham, Edmond ; Lanoye, Autumn ; Harris, Melissa ; Martin, Corby ; Kaufman, Adam ; Foster, Gary ; Cardel, Michelle</creatorcontrib><description><![CDATA[Background: Lifestyle interventions improve glycemic control in adults with type 2 diabetes (T2D) but are expensive and have limited accessibility. We recently demonstrated the efficacy of a virtual diabetes-tailored weight management program (WW, formerly Weight Watchers) on glycemic control in adults with T2D. The goal of this work was to examine effects by HbA1c at trial entry. Methods: This was a prospective 24-week single arm, three-site clinical trial in adults (N=136) with T2D and a BMI between 27-50 kg/m2; 62% (n=84) had a baseline HbA1c between 7-8% and 38% (n=52) between 8-11%. Participants received a 24-wk intervention, which included the WW digital program tailored for people with T2D (virtual workshops + the WW App). Assessments occurred at 0, wk 12, and wk 24. Primary outcome was change in HbA1c at 24 wks (83% retention). Secondary outcomes were changes in weight and the Diabetes Distress Scale (DDS). In an intent-to-treat analysis, generalized linear effects models were used. Results: Participants were 56.8 ± 0.8 y, 80.2% female, 62.2% non-Hispanic White. Mean baseline values for participants <=8% vs. >8% were: BMI=36.6+0.6 kg/m2 vs. 37.4+.8 kg/m2; HbA1c=7.4+0.1% vs. 8.95+1%; weight=99.7+1.9 kg vs. 103.5+2.4kg; total DDS score=2.1+0.1 vs. 2.7+1. HbA1c decreased for both groups over time (<=8% = 0.3±0.1% at wk 12 and 0.4±0.1% at wk 24, both p <.01; >8% = 1.1±0.1% at wk 12 and 1.4±0.2% at wk 24, both p <.0001). Body weight decreased for both groups (<=8% = 4±0.5% at wk 12 and 5.1±0.5% at wk 24, both p <.0001; >8% = 3.72+0.7% at wk 12 and 5+0.7% at wk 24, both p <.0001). Regimen related distress improved for pts <=8% (0.3+0.1 at wk 12 and 0.4+0.2 at wk 24, both p<.05); total DDS scores improved for pts >8% (0.4+0.1 at wk 12 and 0.6+0.2 at wk 24, both p<.01). Conclusions: The widely available virtual WW program, modified for those with T2D, had favorable and clinically meaningful effects on glycemic control, body weight, and diabetes distress for adults with T2D. Effects on glycemic control were most robust for those with HbA1c >8% at trial entry.]]></description><identifier>ISSN: 1930-7381</identifier><identifier>EISSN: 1930-739X</identifier><language>eng</language><publisher>Silver Spring: Blackwell Publishing Ltd</publisher><subject>Diabetes</subject><ispartof>Obesity (Silver Spring, Md.), 2022-11, Vol.30, p.36-37</ispartof><rights>Copyright Blackwell Publishing Ltd. Nov 2022</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782</link.rule.ids></links><search><creatorcontrib>LaRose, Jessica Gokee</creatorcontrib><creatorcontrib>Anton, Stephen</creatorcontrib><creatorcontrib>Apolzan, John</creatorcontrib><creatorcontrib>Beyl, Robbie</creatorcontrib><creatorcontrib>Greenway, Frank</creatorcontrib><creatorcontrib>Wickham, Edmond</creatorcontrib><creatorcontrib>Lanoye, Autumn</creatorcontrib><creatorcontrib>Harris, Melissa</creatorcontrib><creatorcontrib>Martin, Corby</creatorcontrib><creatorcontrib>Kaufman, Adam</creatorcontrib><creatorcontrib>Foster, Gary</creatorcontrib><creatorcontrib>Cardel, Michelle</creatorcontrib><title>Virtual Lifestyle Intervention Tailored for Adults with Type 2 Diabetes: Effects by Baseline HbA1c</title><title>Obesity (Silver Spring, Md.)</title><description><![CDATA[Background: Lifestyle interventions improve glycemic control in adults with type 2 diabetes (T2D) but are expensive and have limited accessibility. We recently demonstrated the efficacy of a virtual diabetes-tailored weight management program (WW, formerly Weight Watchers) on glycemic control in adults with T2D. The goal of this work was to examine effects by HbA1c at trial entry. Methods: This was a prospective 24-week single arm, three-site clinical trial in adults (N=136) with T2D and a BMI between 27-50 kg/m2; 62% (n=84) had a baseline HbA1c between 7-8% and 38% (n=52) between 8-11%. Participants received a 24-wk intervention, which included the WW digital program tailored for people with T2D (virtual workshops + the WW App). Assessments occurred at 0, wk 12, and wk 24. Primary outcome was change in HbA1c at 24 wks (83% retention). Secondary outcomes were changes in weight and the Diabetes Distress Scale (DDS). In an intent-to-treat analysis, generalized linear effects models were used. Results: Participants were 56.8 ± 0.8 y, 80.2% female, 62.2% non-Hispanic White. Mean baseline values for participants <=8% vs. >8% were: BMI=36.6+0.6 kg/m2 vs. 37.4+.8 kg/m2; HbA1c=7.4+0.1% vs. 8.95+1%; weight=99.7+1.9 kg vs. 103.5+2.4kg; total DDS score=2.1+0.1 vs. 2.7+1. HbA1c decreased for both groups over time (<=8% = 0.3±0.1% at wk 12 and 0.4±0.1% at wk 24, both p <.01; >8% = 1.1±0.1% at wk 12 and 1.4±0.2% at wk 24, both p <.0001). Body weight decreased for both groups (<=8% = 4±0.5% at wk 12 and 5.1±0.5% at wk 24, both p <.0001; >8% = 3.72+0.7% at wk 12 and 5+0.7% at wk 24, both p <.0001). Regimen related distress improved for pts <=8% (0.3+0.1 at wk 12 and 0.4+0.2 at wk 24, both p<.05); total DDS scores improved for pts >8% (0.4+0.1 at wk 12 and 0.6+0.2 at wk 24, both p<.01). Conclusions: The widely available virtual WW program, modified for those with T2D, had favorable and clinically meaningful effects on glycemic control, body weight, and diabetes distress for adults with T2D. Effects on glycemic control were most robust for those with HbA1c >8% at trial entry.]]></description><subject>Diabetes</subject><issn>1930-7381</issn><issn>1930-739X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNqNjckKwjAURYMoOP7DA9dC2lir7uqEgssi7iRtXzASkppB6d_bhbh2dS6cC6dDBtGK0VnKVtfuby-jPhk696B0vqBJNCDFRVofuIKzFOh8oxBO2qN9ofbSaMi5VMZiBcJYyKqgvIO39HfImxohhp3kBXp0a9gLgWVriwY23KGSGuFYZFE5Jj3BlcPJlyMyPezz7XFWW_MMbfT2MMHqVt3iNJknCUtZzP57fQBjGkXy</recordid><startdate>20221101</startdate><enddate>20221101</enddate><creator>LaRose, Jessica Gokee</creator><creator>Anton, Stephen</creator><creator>Apolzan, John</creator><creator>Beyl, Robbie</creator><creator>Greenway, Frank</creator><creator>Wickham, Edmond</creator><creator>Lanoye, Autumn</creator><creator>Harris, Melissa</creator><creator>Martin, Corby</creator><creator>Kaufman, Adam</creator><creator>Foster, Gary</creator><creator>Cardel, Michelle</creator><general>Blackwell Publishing Ltd</general><scope>K9.</scope></search><sort><creationdate>20221101</creationdate><title>Virtual Lifestyle Intervention Tailored for Adults with Type 2 Diabetes: Effects by Baseline HbA1c</title><author>LaRose, Jessica Gokee ; Anton, Stephen ; Apolzan, John ; Beyl, Robbie ; Greenway, Frank ; Wickham, Edmond ; Lanoye, Autumn ; Harris, Melissa ; Martin, Corby ; Kaufman, Adam ; Foster, Gary ; Cardel, Michelle</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-proquest_journals_27545537323</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Diabetes</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>LaRose, Jessica Gokee</creatorcontrib><creatorcontrib>Anton, Stephen</creatorcontrib><creatorcontrib>Apolzan, John</creatorcontrib><creatorcontrib>Beyl, Robbie</creatorcontrib><creatorcontrib>Greenway, Frank</creatorcontrib><creatorcontrib>Wickham, Edmond</creatorcontrib><creatorcontrib>Lanoye, Autumn</creatorcontrib><creatorcontrib>Harris, Melissa</creatorcontrib><creatorcontrib>Martin, Corby</creatorcontrib><creatorcontrib>Kaufman, Adam</creatorcontrib><creatorcontrib>Foster, Gary</creatorcontrib><creatorcontrib>Cardel, Michelle</creatorcontrib><collection>ProQuest Health & Medical Complete (Alumni)</collection><jtitle>Obesity (Silver Spring, Md.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>LaRose, Jessica Gokee</au><au>Anton, Stephen</au><au>Apolzan, John</au><au>Beyl, Robbie</au><au>Greenway, Frank</au><au>Wickham, Edmond</au><au>Lanoye, Autumn</au><au>Harris, Melissa</au><au>Martin, Corby</au><au>Kaufman, Adam</au><au>Foster, Gary</au><au>Cardel, Michelle</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Virtual Lifestyle Intervention Tailored for Adults with Type 2 Diabetes: Effects by Baseline HbA1c</atitle><jtitle>Obesity (Silver Spring, Md.)</jtitle><date>2022-11-01</date><risdate>2022</risdate><volume>30</volume><spage>36</spage><epage>37</epage><pages>36-37</pages><issn>1930-7381</issn><eissn>1930-739X</eissn><abstract><![CDATA[Background: Lifestyle interventions improve glycemic control in adults with type 2 diabetes (T2D) but are expensive and have limited accessibility. We recently demonstrated the efficacy of a virtual diabetes-tailored weight management program (WW, formerly Weight Watchers) on glycemic control in adults with T2D. The goal of this work was to examine effects by HbA1c at trial entry. Methods: This was a prospective 24-week single arm, three-site clinical trial in adults (N=136) with T2D and a BMI between 27-50 kg/m2; 62% (n=84) had a baseline HbA1c between 7-8% and 38% (n=52) between 8-11%. Participants received a 24-wk intervention, which included the WW digital program tailored for people with T2D (virtual workshops + the WW App). Assessments occurred at 0, wk 12, and wk 24. Primary outcome was change in HbA1c at 24 wks (83% retention). Secondary outcomes were changes in weight and the Diabetes Distress Scale (DDS). In an intent-to-treat analysis, generalized linear effects models were used. Results: Participants were 56.8 ± 0.8 y, 80.2% female, 62.2% non-Hispanic White. Mean baseline values for participants <=8% vs. >8% were: BMI=36.6+0.6 kg/m2 vs. 37.4+.8 kg/m2; HbA1c=7.4+0.1% vs. 8.95+1%; weight=99.7+1.9 kg vs. 103.5+2.4kg; total DDS score=2.1+0.1 vs. 2.7+1. HbA1c decreased for both groups over time (<=8% = 0.3±0.1% at wk 12 and 0.4±0.1% at wk 24, both p <.01; >8% = 1.1±0.1% at wk 12 and 1.4±0.2% at wk 24, both p <.0001). Body weight decreased for both groups (<=8% = 4±0.5% at wk 12 and 5.1±0.5% at wk 24, both p <.0001; >8% = 3.72+0.7% at wk 12 and 5+0.7% at wk 24, both p <.0001). Regimen related distress improved for pts <=8% (0.3+0.1 at wk 12 and 0.4+0.2 at wk 24, both p<.05); total DDS scores improved for pts >8% (0.4+0.1 at wk 12 and 0.6+0.2 at wk 24, both p<.01). Conclusions: The widely available virtual WW program, modified for those with T2D, had favorable and clinically meaningful effects on glycemic control, body weight, and diabetes distress for adults with T2D. Effects on glycemic control were most robust for those with HbA1c >8% at trial entry.]]></abstract><cop>Silver Spring</cop><pub>Blackwell Publishing Ltd</pub></addata></record> |
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| subjects | Diabetes |
| title | Virtual Lifestyle Intervention Tailored for Adults with Type 2 Diabetes: Effects by Baseline HbA1c |
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