Synthesis and Anti-Monoamine Oxidase Activity of 2-Substituted 4,4-Dimethyl-1,2,3,4-tetrahydroisoquinoline Derivatives

Treatment of N -benzyl-2-methylprop-2-en-1-amine with a mixture of concentrated sulfuric acid and 85% phosphoric acid gave 4,4-dimethyl-1,2,3,4-tetrahydroisoquinoline which was reacted with aromatic carboxylic acid chlorides, and the subsequent reduction afforded 2-arylalkyl tetrahydroisoquinolines....

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Veröffentlicht in:Russian journal of organic chemistry 2022-10, Vol.58 (10), p.1409-1415
Hauptverfasser: Aghekyan, A. A., Arustamyan, Zh. S., Margaryan, R. E., Panosyan, H. A., Grigoryan, A. S., Gasparyan, H. V.
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Sprache:eng
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