Heat shock‐induced heme oxygenase‐1 expression in a mouse hepatoma cell line is dependent on HSF1 and modified by NRF2 and BACH1

The induction mechanism of heme oxygenase‐1 (HO‐1) by heat shock (HS) is still unknown. Here, we discovered that HS activates the HO‐1 expression in a mouse hepatoma cell line (Hepa 1–6). Knockdown experiments showed that the HS‐induced HO‐1 expression was dependent on HS factor 1 (HSF1). A chromati...

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