Does hormone replacement therapy in post-menopausal women have any effect upon nasal physiology?
Previous studies have suggested that the female menstrual cycle, pregnancy and the oral contraceptive pill have an effect upon nasal physiology. This study aimed to assess the effects upon nasal physiology of female hormone replacement therapy in post-menopausal women. This has not been previously s...
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| Veröffentlicht in: | Journal of laryngology and otology 2008-07, Vol.122 (7), p.707-710 |
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| container_title | Journal of laryngology and otology |
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| creator | Wild, D C Philpott, C M Wolstenholme, C R Murty, G E |
| description | Previous studies have suggested that the female menstrual cycle, pregnancy and the oral contraceptive pill have an effect upon nasal physiology.
This study aimed to assess the effects upon nasal physiology of female hormone replacement therapy in post-menopausal women. This has not been previously studied.
Twenty post-menopausal women (age range 36 to 70 years; mean age 57.0 years) underwent measurements of the nasal airway, including anterior rhinoscopy, peak nasal inspiratory flow rate, acoustic rhinometry, anterior rhinomanometry, mucociliary clearance time and rhinitis quality of life questionnaire. Measurements of nasal patency were recorded prior to commencing hormone replacement therapy and at a time point 77-195 days (mean 101.9 days) following commencement.
There was no statistical difference found for any of the variables, using the paired t-test (p > 0.05 for all).
Female hormone replacement therapy has no discernable effect upon nasal physiology and should not be considered a cause of rhinitic symptoms. |
| doi_str_mv | 10.1017/S0022215107001612 |
| format | Article |
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This study aimed to assess the effects upon nasal physiology of female hormone replacement therapy in post-menopausal women. This has not been previously studied.
Twenty post-menopausal women (age range 36 to 70 years; mean age 57.0 years) underwent measurements of the nasal airway, including anterior rhinoscopy, peak nasal inspiratory flow rate, acoustic rhinometry, anterior rhinomanometry, mucociliary clearance time and rhinitis quality of life questionnaire. Measurements of nasal patency were recorded prior to commencing hormone replacement therapy and at a time point 77-195 days (mean 101.9 days) following commencement.
There was no statistical difference found for any of the variables, using the paired t-test (p > 0.05 for all).
Female hormone replacement therapy has no discernable effect upon nasal physiology and should not be considered a cause of rhinitic symptoms.</description><identifier>ISSN: 0022-2151</identifier><identifier>EISSN: 1748-5460</identifier><identifier>DOI: 10.1017/S0022215107001612</identifier><identifier>PMID: 18267047</identifier><identifier>CODEN: JLOTAX</identifier><language>eng</language><publisher>Cambridge, UK: Cambridge University Press</publisher><subject>Acoustics ; Adult ; Aged ; Biological and medical sciences ; Contraceptives, Oral - pharmacology ; Female ; Hormone Replacement Therapy ; Hormone Replacement Therapy - adverse effects ; Humans ; Inspiratory Capacity - drug effects ; Inspiratory Capacity - physiology ; Medical sciences ; Menstrual Cycle - physiology ; Menstruation ; Middle Aged ; Mucociliary Clearance - drug effects ; Mucociliary Clearance - physiology ; Nasal Cavity ; Nasal Cavity - drug effects ; Nasal Cavity - physiology ; Non tumoral diseases ; Otorhinolaryngology. Stomatology ; Patients ; Physiology ; Postmenopause - drug effects ; Postmenopause - physiology ; Pregnancy ; Quality of life ; Quality of Life - psychology ; Questionnaires ; Rhinitis ; Rhinitis - chemically induced ; Rhinomanometry - methods ; Sinusitis ; Treatment Outcome ; Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology ; Womens health</subject><ispartof>Journal of laryngology and otology, 2008-07, Vol.122 (7), p.707-710</ispartof><rights>Copyright © JLO (1984) Limited 2008</rights><rights>2008 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c438t-ef9215af199af430646d3aebf94ecceb7eb9eb9a5ed7e807e3afb93e3455aa53</citedby><cites>FETCH-LOGICAL-c438t-ef9215af199af430646d3aebf94ecceb7eb9eb9a5ed7e807e3afb93e3455aa53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.cambridge.org/core/product/identifier/S0022215107001612/type/journal_article$$EHTML$$P50$$Gcambridge$$H</linktohtml><link.rule.ids>164,314,780,784,27923,27924,55627</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=20472036$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18267047$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wild, D C</creatorcontrib><creatorcontrib>Philpott, C M</creatorcontrib><creatorcontrib>Wolstenholme, C R</creatorcontrib><creatorcontrib>Murty, G E</creatorcontrib><title>Does hormone replacement therapy in post-menopausal women have any effect upon nasal physiology?</title><title>Journal of laryngology and otology</title><addtitle>J. Laryngol. Otol</addtitle><description>Previous studies have suggested that the female menstrual cycle, pregnancy and the oral contraceptive pill have an effect upon nasal physiology.
This study aimed to assess the effects upon nasal physiology of female hormone replacement therapy in post-menopausal women. This has not been previously studied.
Twenty post-menopausal women (age range 36 to 70 years; mean age 57.0 years) underwent measurements of the nasal airway, including anterior rhinoscopy, peak nasal inspiratory flow rate, acoustic rhinometry, anterior rhinomanometry, mucociliary clearance time and rhinitis quality of life questionnaire. Measurements of nasal patency were recorded prior to commencing hormone replacement therapy and at a time point 77-195 days (mean 101.9 days) following commencement.
There was no statistical difference found for any of the variables, using the paired t-test (p > 0.05 for all).
Female hormone replacement therapy has no discernable effect upon nasal physiology and should not be considered a cause of rhinitic symptoms.</description><subject>Acoustics</subject><subject>Adult</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Contraceptives, Oral - pharmacology</subject><subject>Female</subject><subject>Hormone Replacement Therapy</subject><subject>Hormone Replacement Therapy - adverse effects</subject><subject>Humans</subject><subject>Inspiratory Capacity - drug effects</subject><subject>Inspiratory Capacity - physiology</subject><subject>Medical sciences</subject><subject>Menstrual Cycle - physiology</subject><subject>Menstruation</subject><subject>Middle Aged</subject><subject>Mucociliary Clearance - drug effects</subject><subject>Mucociliary Clearance - physiology</subject><subject>Nasal Cavity</subject><subject>Nasal Cavity - drug effects</subject><subject>Nasal Cavity - physiology</subject><subject>Non tumoral diseases</subject><subject>Otorhinolaryngology. Stomatology</subject><subject>Patients</subject><subject>Physiology</subject><subject>Postmenopause - drug effects</subject><subject>Postmenopause - physiology</subject><subject>Pregnancy</subject><subject>Quality of life</subject><subject>Quality of Life - psychology</subject><subject>Questionnaires</subject><subject>Rhinitis</subject><subject>Rhinitis - chemically induced</subject><subject>Rhinomanometry - methods</subject><subject>Sinusitis</subject><subject>Treatment Outcome</subject><subject>Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology</subject><subject>Womens health</subject><issn>0022-2151</issn><issn>1748-5460</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp1kE9v1DAQxS0EokvLB-CCLCSOof4XOzkhtKUFqRKqtnczyY67KUkc7KSQb4-jjdoDqmTJst9vZt48Qt5x9okzbs53jAkheM6ZYYxrLl6QDTeqyHKl2UuyWeRs0U_ImxjvWYIME6_JCS-ENkyZDfl54THSgw-d75EGHFqoscN-pOMBAwwzbXo6-Dhm6dMPMEVo6R-fHvQAD0ihnyk6h_VIp8H3tIcFGA5zbHzr7-bPZ-SVgzbi2_U-JbeXX2-337LrH1fft1-us1rJYszQlckoOF6W4JRkWum9BKxcqbCusTJYlelAjnuDBTMowVWlRKnyHCCXp-TDse0Q_O8J42jv_RT6NNEKo4wpmNYJ4keoDj7GgM4OoekgzJYzuyRq_0s01bxfG09Vh_unijXCBHxcAYg1tC5AXzfxkROJEUwuw7Mj18QR_z7qEH5ZbaTJrb66sTtxuWPbC2OXjeRqFroqNPs7fFrpebv_AEoRnWE</recordid><startdate>20080701</startdate><enddate>20080701</enddate><creator>Wild, D C</creator><creator>Philpott, C M</creator><creator>Wolstenholme, C R</creator><creator>Murty, G E</creator><general>Cambridge University Press</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>S0X</scope></search><sort><creationdate>20080701</creationdate><title>Does hormone replacement therapy in post-menopausal women have any effect upon nasal physiology?</title><author>Wild, D C ; Philpott, C M ; Wolstenholme, C R ; Murty, G E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c438t-ef9215af199af430646d3aebf94ecceb7eb9eb9a5ed7e807e3afb93e3455aa53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Acoustics</topic><topic>Adult</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Contraceptives, Oral - pharmacology</topic><topic>Female</topic><topic>Hormone Replacement Therapy</topic><topic>Hormone Replacement Therapy - adverse effects</topic><topic>Humans</topic><topic>Inspiratory Capacity - drug effects</topic><topic>Inspiratory Capacity - physiology</topic><topic>Medical sciences</topic><topic>Menstrual Cycle - physiology</topic><topic>Menstruation</topic><topic>Middle Aged</topic><topic>Mucociliary Clearance - drug effects</topic><topic>Mucociliary Clearance - physiology</topic><topic>Nasal Cavity</topic><topic>Nasal Cavity - drug effects</topic><topic>Nasal Cavity - physiology</topic><topic>Non tumoral diseases</topic><topic>Otorhinolaryngology. Stomatology</topic><topic>Patients</topic><topic>Physiology</topic><topic>Postmenopause - drug effects</topic><topic>Postmenopause - physiology</topic><topic>Pregnancy</topic><topic>Quality of life</topic><topic>Quality of Life - psychology</topic><topic>Questionnaires</topic><topic>Rhinitis</topic><topic>Rhinitis - chemically induced</topic><topic>Rhinomanometry - methods</topic><topic>Sinusitis</topic><topic>Treatment Outcome</topic><topic>Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology</topic><topic>Womens health</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wild, D C</creatorcontrib><creatorcontrib>Philpott, C M</creatorcontrib><creatorcontrib>Wolstenholme, C R</creatorcontrib><creatorcontrib>Murty, G E</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Nursing & Allied Health Database</collection><collection>Neurosciences Abstracts</collection><collection>ProQuest Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>ProQuest Science Journals</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>SIRS Editorial</collection><jtitle>Journal of laryngology and otology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wild, D C</au><au>Philpott, C M</au><au>Wolstenholme, C R</au><au>Murty, G E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Does hormone replacement therapy in post-menopausal women have any effect upon nasal physiology?</atitle><jtitle>Journal of laryngology and otology</jtitle><addtitle>J. Laryngol. Otol</addtitle><date>2008-07-01</date><risdate>2008</risdate><volume>122</volume><issue>7</issue><spage>707</spage><epage>710</epage><pages>707-710</pages><issn>0022-2151</issn><eissn>1748-5460</eissn><coden>JLOTAX</coden><abstract>Previous studies have suggested that the female menstrual cycle, pregnancy and the oral contraceptive pill have an effect upon nasal physiology.
This study aimed to assess the effects upon nasal physiology of female hormone replacement therapy in post-menopausal women. This has not been previously studied.
Twenty post-menopausal women (age range 36 to 70 years; mean age 57.0 years) underwent measurements of the nasal airway, including anterior rhinoscopy, peak nasal inspiratory flow rate, acoustic rhinometry, anterior rhinomanometry, mucociliary clearance time and rhinitis quality of life questionnaire. Measurements of nasal patency were recorded prior to commencing hormone replacement therapy and at a time point 77-195 days (mean 101.9 days) following commencement.
There was no statistical difference found for any of the variables, using the paired t-test (p > 0.05 for all).
Female hormone replacement therapy has no discernable effect upon nasal physiology and should not be considered a cause of rhinitic symptoms.</abstract><cop>Cambridge, UK</cop><pub>Cambridge University Press</pub><pmid>18267047</pmid><doi>10.1017/S0022215107001612</doi><tpages>4</tpages></addata></record> |
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| ispartof | Journal of laryngology and otology, 2008-07, Vol.122 (7), p.707-710 |
| issn | 0022-2151 1748-5460 |
| language | eng |
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| source | MEDLINE; Cambridge Journals |
| subjects | Acoustics Adult Aged Biological and medical sciences Contraceptives, Oral - pharmacology Female Hormone Replacement Therapy Hormone Replacement Therapy - adverse effects Humans Inspiratory Capacity - drug effects Inspiratory Capacity - physiology Medical sciences Menstrual Cycle - physiology Menstruation Middle Aged Mucociliary Clearance - drug effects Mucociliary Clearance - physiology Nasal Cavity Nasal Cavity - drug effects Nasal Cavity - physiology Non tumoral diseases Otorhinolaryngology. Stomatology Patients Physiology Postmenopause - drug effects Postmenopause - physiology Pregnancy Quality of life Quality of Life - psychology Questionnaires Rhinitis Rhinitis - chemically induced Rhinomanometry - methods Sinusitis Treatment Outcome Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology Womens health |
| title | Does hormone replacement therapy in post-menopausal women have any effect upon nasal physiology? |
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