Abies koreana Essential Oil Inhibits Drug-Resistant Skin Pathogen Growth and LPS-Induced Inflammatory Effects of Murine Macrophage
Since acne vulgaris is the combined result of a bacterial infection and the inflammatory response to that infection, we examined whether Abies koreana essential oil (AKE) possessed anti-inflammatory and antibacterial activities against skin pathogens. In this study, AKE showed excellent antibacteria...
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| Veröffentlicht in: | Lipids 2009-05, Vol.44 (5), p.471-476 |
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| creator | Yoon, Weon-Jong Kim, Sang-Suk Oh, Tae-Heon Lee, Nam Ho Hyun, Chang-Gu |
| description | Since acne vulgaris is the combined result of a bacterial infection and the inflammatory response to that infection, we examined whether Abies koreana essential oil (AKE) possessed anti-inflammatory and antibacterial activities against skin pathogens. In this study, AKE showed excellent antibacterial activities against drug-susceptible and -resistant Propionibacterium acnes and Staphylococcus epidermidis, which are acne-causing bacteria. In addition, AKE reduced the LPS-induced secretion of tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), IL-6, NO and PGE₂ in RAW 264.7 cells, indicating that it has anti-inflammatory effects. Therefore, we suggest that AKE may be an attractive candidate for promoting skin health. |
| doi_str_mv | 10.1007/s11745-009-3297-3 |
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In this study, AKE showed excellent antibacterial activities against drug-susceptible and -resistant Propionibacterium acnes and Staphylococcus epidermidis, which are acne-causing bacteria. In addition, AKE reduced the LPS-induced secretion of tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), IL-6, NO and PGE₂ in RAW 264.7 cells, indicating that it has anti-inflammatory effects. Therefore, we suggest that AKE may be an attractive candidate for promoting skin health.</description><identifier>ISSN: 0024-4201</identifier><identifier>EISSN: 1558-9307</identifier><identifier>DOI: 10.1007/s11745-009-3297-3</identifier><identifier>PMID: 19350303</identifier><language>eng</language><publisher>Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag</publisher><subject>Abies - chemistry ; Abies koreana ; acne ; Acne vulgaris ; Acne Vulgaris - microbiology ; Animals ; Anti-Bacterial Agents - pharmacology ; anti-inflammatory activity ; Anti-Inflammatory Agents - pharmacology ; antibacterial properties ; Bacterial diseases ; bacterial infections ; Biomarkers ; Biomedical and Life Sciences ; Cell Line ; Communication ; cultured cells ; Drug Resistance ; Essential oil ; Essential oils ; Inflammation ; Inflammation - chemically induced ; Inflammation - drug therapy ; interleukin-1 ; interleukin-6 ; Life Sciences ; Lipidology ; Lipopolysaccharides - pharmacology ; macrophages ; Macrophages - drug effects ; Macrophages - microbiology ; Medical Biochemistry ; Medicinal Chemistry ; medicinal properties ; Mice ; Microbial Genetics and Genomics ; Microbial Sensitivity Tests ; Neurochemistry ; nitric oxide ; Nutrition ; Oils, Volatile - pharmacology ; Pathogens ; Propionibacterium acnes ; Propionibacterium acnes - drug effects ; prostaglandins ; Skin pathogen ; Staphylococcus epidermidis ; Staphylococcus epidermidis - drug effects ; tumor necrosis factor-alpha</subject><ispartof>Lipids, 2009-05, Vol.44 (5), p.471-476</ispartof><rights>AOCS 2009</rights><rights>2009 American Oil Chemists' Society (AOCS)</rights><rights>Copyright AOCS Press May 2009</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5071-e468b452d246c8569efa515bb1806144c10ce52e4c81e99245699cc1ee87ade33</citedby><cites>FETCH-LOGICAL-c5071-e468b452d246c8569efa515bb1806144c10ce52e4c81e99245699cc1ee87ade33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11745-009-3297-3$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11745-009-3297-3$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,777,781,1412,27905,27906,41469,42538,45555,45556,51300</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19350303$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yoon, Weon-Jong</creatorcontrib><creatorcontrib>Kim, Sang-Suk</creatorcontrib><creatorcontrib>Oh, Tae-Heon</creatorcontrib><creatorcontrib>Lee, Nam Ho</creatorcontrib><creatorcontrib>Hyun, Chang-Gu</creatorcontrib><title>Abies koreana Essential Oil Inhibits Drug-Resistant Skin Pathogen Growth and LPS-Induced Inflammatory Effects of Murine Macrophage</title><title>Lipids</title><addtitle>Lipids</addtitle><addtitle>Lipids</addtitle><description>Since acne vulgaris is the combined result of a bacterial infection and the inflammatory response to that infection, we examined whether Abies koreana essential oil (AKE) possessed anti-inflammatory and antibacterial activities against skin pathogens. In this study, AKE showed excellent antibacterial activities against drug-susceptible and -resistant Propionibacterium acnes and Staphylococcus epidermidis, which are acne-causing bacteria. In addition, AKE reduced the LPS-induced secretion of tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), IL-6, NO and PGE₂ in RAW 264.7 cells, indicating that it has anti-inflammatory effects. Therefore, we suggest that AKE may be an attractive candidate for promoting skin health.</description><subject>Abies - chemistry</subject><subject>Abies koreana</subject><subject>acne</subject><subject>Acne vulgaris</subject><subject>Acne Vulgaris - microbiology</subject><subject>Animals</subject><subject>Anti-Bacterial Agents - pharmacology</subject><subject>anti-inflammatory activity</subject><subject>Anti-Inflammatory Agents - pharmacology</subject><subject>antibacterial properties</subject><subject>Bacterial diseases</subject><subject>bacterial infections</subject><subject>Biomarkers</subject><subject>Biomedical and Life Sciences</subject><subject>Cell Line</subject><subject>Communication</subject><subject>cultured cells</subject><subject>Drug Resistance</subject><subject>Essential oil</subject><subject>Essential oils</subject><subject>Inflammation</subject><subject>Inflammation - chemically induced</subject><subject>Inflammation - drug therapy</subject><subject>interleukin-1</subject><subject>interleukin-6</subject><subject>Life Sciences</subject><subject>Lipidology</subject><subject>Lipopolysaccharides - pharmacology</subject><subject>macrophages</subject><subject>Macrophages - drug effects</subject><subject>Macrophages - microbiology</subject><subject>Medical Biochemistry</subject><subject>Medicinal Chemistry</subject><subject>medicinal properties</subject><subject>Mice</subject><subject>Microbial Genetics and Genomics</subject><subject>Microbial Sensitivity Tests</subject><subject>Neurochemistry</subject><subject>nitric oxide</subject><subject>Nutrition</subject><subject>Oils, Volatile - pharmacology</subject><subject>Pathogens</subject><subject>Propionibacterium acnes</subject><subject>Propionibacterium acnes - drug effects</subject><subject>prostaglandins</subject><subject>Skin pathogen</subject><subject>Staphylococcus epidermidis</subject><subject>Staphylococcus epidermidis - drug effects</subject><subject>tumor necrosis factor-alpha</subject><issn>0024-4201</issn><issn>1558-9307</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqFkk9v0zAchi0EYmXwAbiAxd3gv0l8nLYyKnVaRdnZcpxfUm-pU-xEU698clyl0m5wsiy9z-tXj4zQR0a_MkrLb4mxUipCqSaC65KIV2jBlKqIFrR8jRaUckkkp-wCvUvpMV-Z1OotumBaKCqoWKA_V7WHhJ-GCDZYvEwJwuhtj-99j1dh52s_JnwTp478hOTTaMOIt08-4I0dd0MHAd_G4XncYRsavN5sySo0k4Mmw21v93s7DvGIl20LLhcNLb6bog-A76yLw2FnO3iP3rS2T_DhfF6ih-_LX9c_yPr-dnV9tSZO0ZIRkEVVS8UbLgtXqUJDaxVTdc0qWjApHaMOFAfpKgZac5kj2jkGUJW2ASEu0Ze59xCH3xOk0TwOUwz5ScNLmUVqeQqxOZTXpRShNYfo9zYeDaPmJN3M0k2Wbk7SzYn5dC6e6j00L8TZcg6Uc-DZ93D8f6NZrzY3VJYsk3wmU4ZCB_Fl87_2fJ6h1g7GdtEn87DNv0BQVnBVCCH-Am2Mphg</recordid><startdate>200905</startdate><enddate>200905</enddate><creator>Yoon, Weon-Jong</creator><creator>Kim, Sang-Suk</creator><creator>Oh, Tae-Heon</creator><creator>Lee, Nam Ho</creator><creator>Hyun, Chang-Gu</creator><general>Berlin/Heidelberg : Springer-Verlag</general><general>Springer-Verlag</general><general>Springer‐Verlag</general><general>Springer Nature B.V</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7QP</scope><scope>7QR</scope><scope>7T7</scope><scope>7TK</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BKSAR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>P64</scope><scope>PCBAR</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope></search><sort><creationdate>200905</creationdate><title>Abies koreana Essential Oil Inhibits Drug-Resistant Skin Pathogen Growth and LPS-Induced Inflammatory Effects of Murine Macrophage</title><author>Yoon, Weon-Jong ; Kim, Sang-Suk ; Oh, Tae-Heon ; Lee, Nam Ho ; Hyun, Chang-Gu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5071-e468b452d246c8569efa515bb1806144c10ce52e4c81e99245699cc1ee87ade33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Abies - chemistry</topic><topic>Abies koreana</topic><topic>acne</topic><topic>Acne vulgaris</topic><topic>Acne Vulgaris - microbiology</topic><topic>Animals</topic><topic>Anti-Bacterial Agents - pharmacology</topic><topic>anti-inflammatory activity</topic><topic>Anti-Inflammatory Agents - pharmacology</topic><topic>antibacterial properties</topic><topic>Bacterial diseases</topic><topic>bacterial infections</topic><topic>Biomarkers</topic><topic>Biomedical and Life Sciences</topic><topic>Cell Line</topic><topic>Communication</topic><topic>cultured cells</topic><topic>Drug Resistance</topic><topic>Essential oil</topic><topic>Essential oils</topic><topic>Inflammation</topic><topic>Inflammation - chemically induced</topic><topic>Inflammation - drug therapy</topic><topic>interleukin-1</topic><topic>interleukin-6</topic><topic>Life Sciences</topic><topic>Lipidology</topic><topic>Lipopolysaccharides - pharmacology</topic><topic>macrophages</topic><topic>Macrophages - drug effects</topic><topic>Macrophages - microbiology</topic><topic>Medical Biochemistry</topic><topic>Medicinal Chemistry</topic><topic>medicinal properties</topic><topic>Mice</topic><topic>Microbial Genetics and Genomics</topic><topic>Microbial Sensitivity Tests</topic><topic>Neurochemistry</topic><topic>nitric oxide</topic><topic>Nutrition</topic><topic>Oils, Volatile - pharmacology</topic><topic>Pathogens</topic><topic>Propionibacterium acnes</topic><topic>Propionibacterium acnes - drug effects</topic><topic>prostaglandins</topic><topic>Skin pathogen</topic><topic>Staphylococcus epidermidis</topic><topic>Staphylococcus epidermidis - drug effects</topic><topic>tumor necrosis factor-alpha</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yoon, Weon-Jong</creatorcontrib><creatorcontrib>Kim, Sang-Suk</creatorcontrib><creatorcontrib>Oh, Tae-Heon</creatorcontrib><creatorcontrib>Lee, Nam Ho</creatorcontrib><creatorcontrib>Hyun, Chang-Gu</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Earth, Atmospheric & Aquatic Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Earth, Atmospheric & Aquatic Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><jtitle>Lipids</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yoon, Weon-Jong</au><au>Kim, Sang-Suk</au><au>Oh, Tae-Heon</au><au>Lee, Nam Ho</au><au>Hyun, Chang-Gu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Abies koreana Essential Oil Inhibits Drug-Resistant Skin Pathogen Growth and LPS-Induced Inflammatory Effects of Murine Macrophage</atitle><jtitle>Lipids</jtitle><stitle>Lipids</stitle><addtitle>Lipids</addtitle><date>2009-05</date><risdate>2009</risdate><volume>44</volume><issue>5</issue><spage>471</spage><epage>476</epage><pages>471-476</pages><issn>0024-4201</issn><eissn>1558-9307</eissn><abstract>Since acne vulgaris is the combined result of a bacterial infection and the inflammatory response to that infection, we examined whether Abies koreana essential oil (AKE) possessed anti-inflammatory and antibacterial activities against skin pathogens. In this study, AKE showed excellent antibacterial activities against drug-susceptible and -resistant Propionibacterium acnes and Staphylococcus epidermidis, which are acne-causing bacteria. In addition, AKE reduced the LPS-induced secretion of tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), IL-6, NO and PGE₂ in RAW 264.7 cells, indicating that it has anti-inflammatory effects. Therefore, we suggest that AKE may be an attractive candidate for promoting skin health.</abstract><cop>Berlin/Heidelberg</cop><pub>Berlin/Heidelberg : Springer-Verlag</pub><pmid>19350303</pmid><doi>10.1007/s11745-009-3297-3</doi><tpages>6</tpages></addata></record> |
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| subjects | Abies - chemistry Abies koreana acne Acne vulgaris Acne Vulgaris - microbiology Animals Anti-Bacterial Agents - pharmacology anti-inflammatory activity Anti-Inflammatory Agents - pharmacology antibacterial properties Bacterial diseases bacterial infections Biomarkers Biomedical and Life Sciences Cell Line Communication cultured cells Drug Resistance Essential oil Essential oils Inflammation Inflammation - chemically induced Inflammation - drug therapy interleukin-1 interleukin-6 Life Sciences Lipidology Lipopolysaccharides - pharmacology macrophages Macrophages - drug effects Macrophages - microbiology Medical Biochemistry Medicinal Chemistry medicinal properties Mice Microbial Genetics and Genomics Microbial Sensitivity Tests Neurochemistry nitric oxide Nutrition Oils, Volatile - pharmacology Pathogens Propionibacterium acnes Propionibacterium acnes - drug effects prostaglandins Skin pathogen Staphylococcus epidermidis Staphylococcus epidermidis - drug effects tumor necrosis factor-alpha |
| title | Abies koreana Essential Oil Inhibits Drug-Resistant Skin Pathogen Growth and LPS-Induced Inflammatory Effects of Murine Macrophage |
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