Mortality and Blood Pressure in Elderly People with and without Cognitive Impairment
Background: Controversial data are available on the association between mortality, blood pressure and cognitive impairment in the elderly. Objective: To verify the role of blood pressure on mortality in an elderly population with and without cognitive impairment. Methods: A cross-sectional survey wi...
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| Veröffentlicht in: | Gerontology (Basel) 2005-01, Vol.51 (1), p.53-61 |
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| creator | Cacciatore, Francesco Abete, Pasquale de Santis, Domenico Longobardi, Giancarlo Ferrara, Nicola Rengo, Franco |
| description | Background: Controversial data are available on the association between mortality, blood pressure and cognitive impairment in the elderly. Objective: To verify the role of blood pressure on mortality in an elderly population with and without cognitive impairment. Methods: A cross-sectional survey with a 6-year mortality evaluation was conducted in a region of southern Italy in elderly subjects with and without cognitive impairment. Subjects were divided into 4 groups on the basis of systolic, diastolic, mean and pulse blood pressure values. Results: Mortality shows a linear relationship with pulse blood pressure and a U-curve shape for diastolic blood pressure. This phenomenon was more evident in subjects with cognitive impairment showing the greatest risk of mortality at the lowest and highest levels of diastolic blood pressure. Conclusion: The study shows that mortality increases linearly with increasing blood pressure in the elderly. In contrast, mortality shows a U-shape curve for diastolic blood pressure; cognitively impaired patients with the lowest and highest diastolic blood pressures show the greatest relative risk of mortality. |
| doi_str_mv | 10.1159/000081436 |
| format | Article |
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Objective: To verify the role of blood pressure on mortality in an elderly population with and without cognitive impairment. Methods: A cross-sectional survey with a 6-year mortality evaluation was conducted in a region of southern Italy in elderly subjects with and without cognitive impairment. Subjects were divided into 4 groups on the basis of systolic, diastolic, mean and pulse blood pressure values. Results: Mortality shows a linear relationship with pulse blood pressure and a U-curve shape for diastolic blood pressure. This phenomenon was more evident in subjects with cognitive impairment showing the greatest risk of mortality at the lowest and highest levels of diastolic blood pressure. Conclusion: The study shows that mortality increases linearly with increasing blood pressure in the elderly. In contrast, mortality shows a U-shape curve for diastolic blood pressure; cognitively impaired patients with the lowest and highest diastolic blood pressures show the greatest relative risk of mortality.</description><identifier>ISSN: 0304-324X</identifier><identifier>EISSN: 1423-0003</identifier><identifier>DOI: 10.1159/000081436</identifier><identifier>PMID: 15591757</identifier><identifier>CODEN: GERNDJ</identifier><language>eng</language><publisher>Basel, Switzerland: Karger</publisher><subject>Aged ; Aged, 80 and over ; Arterial hypertension. Arterial hypotension ; Biological and medical sciences ; Blood and lymphatic vessels ; Blood Pressure ; Cardiology. Vascular system ; Clinical manifestations. Epidemiology. Investigative techniques. Etiology ; Clinical Section ; Cognition Disorders - complications ; Cross-Sectional Studies ; Female ; Humans ; Hypertension - complications ; Hypertension - mortality ; Hypertension - physiopathology ; Italy ; Male ; Medical sciences ; Risk Factors ; Survival Rate</subject><ispartof>Gerontology (Basel), 2005-01, Vol.51 (1), p.53-61</ispartof><rights>2005 S. Karger AG, Basel</rights><rights>2005 INIST-CNRS</rights><rights>Copyright (c) 2005 S. Karger AG, Basel</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c387t-c0bb5485bb4f0aed73e8ad652ed124d696878952b802dbce0ed25f3f990a70aa3</citedby><cites>FETCH-LOGICAL-c387t-c0bb5485bb4f0aed73e8ad652ed124d696878952b802dbce0ed25f3f990a70aa3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,2423,4010,27900,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=16460454$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15591757$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cacciatore, Francesco</creatorcontrib><creatorcontrib>Abete, Pasquale</creatorcontrib><creatorcontrib>de Santis, Domenico</creatorcontrib><creatorcontrib>Longobardi, Giancarlo</creatorcontrib><creatorcontrib>Ferrara, Nicola</creatorcontrib><creatorcontrib>Rengo, Franco</creatorcontrib><title>Mortality and Blood Pressure in Elderly People with and without Cognitive Impairment</title><title>Gerontology (Basel)</title><addtitle>Gerontology</addtitle><description>Background: Controversial data are available on the association between mortality, blood pressure and cognitive impairment in the elderly. Objective: To verify the role of blood pressure on mortality in an elderly population with and without cognitive impairment. Methods: A cross-sectional survey with a 6-year mortality evaluation was conducted in a region of southern Italy in elderly subjects with and without cognitive impairment. Subjects were divided into 4 groups on the basis of systolic, diastolic, mean and pulse blood pressure values. Results: Mortality shows a linear relationship with pulse blood pressure and a U-curve shape for diastolic blood pressure. This phenomenon was more evident in subjects with cognitive impairment showing the greatest risk of mortality at the lowest and highest levels of diastolic blood pressure. Conclusion: The study shows that mortality increases linearly with increasing blood pressure in the elderly. In contrast, mortality shows a U-shape curve for diastolic blood pressure; cognitively impaired patients with the lowest and highest diastolic blood pressures show the greatest relative risk of mortality.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Arterial hypertension. Arterial hypotension</subject><subject>Biological and medical sciences</subject><subject>Blood and lymphatic vessels</subject><subject>Blood Pressure</subject><subject>Cardiology. Vascular system</subject><subject>Clinical manifestations. Epidemiology. Investigative techniques. Etiology</subject><subject>Clinical Section</subject><subject>Cognition Disorders - complications</subject><subject>Cross-Sectional Studies</subject><subject>Female</subject><subject>Humans</subject><subject>Hypertension - complications</subject><subject>Hypertension - mortality</subject><subject>Hypertension - physiopathology</subject><subject>Italy</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Risk Factors</subject><subject>Survival Rate</subject><issn>0304-324X</issn><issn>1423-0003</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNpt0M1rFDEYBvAgSrv9OHgWJBQqeBib78kc67LWQsVSWvA2ZCbv1NTMZJrMKPvfm3aXLoi55IMfbx4ehN5S8olSWZ2RvDQVXL1CCyoYL_Kdv0YLwokoOBM_9tFBSg_5kTBK9tA-lbKipSwX6PZbiJPxblpjM1j82Ydg8XWElOYI2A145S1Ev8bXEEYP-I-bfj7Lp0OYJ7wM94Ob3G_Al_1oXOxhmI7Qm874BMfb_RDdfVndLr8WV98vLpfnV0XLdTkVLWkaKbRsGtERA7bkoI1VkoGlTFhVKV3qSrJGE2abFghYJjveVRUxJTGGH6IPm7ljDI8zpKnuXWrBezNAmFOtSs6F4DrDk3_gQ5jjkLPVrBRKa8VURh83qI0hpQhdPUbXm7iuKamfeq5fes72_Xbg3PRgd3JbbAanW2BSa3wXzdC6tHNKKCKk2CX7ZeI9xBdwsbp5_qkebZfRu_-iTZa_DiqYyQ</recordid><startdate>200501</startdate><enddate>200501</enddate><creator>Cacciatore, Francesco</creator><creator>Abete, Pasquale</creator><creator>de Santis, Domenico</creator><creator>Longobardi, Giancarlo</creator><creator>Ferrara, Nicola</creator><creator>Rengo, Franco</creator><general>Karger</general><general>S. 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Arterial hypotension</topic><topic>Biological and medical sciences</topic><topic>Blood and lymphatic vessels</topic><topic>Blood Pressure</topic><topic>Cardiology. Vascular system</topic><topic>Clinical manifestations. Epidemiology. Investigative techniques. Etiology</topic><topic>Clinical Section</topic><topic>Cognition Disorders - complications</topic><topic>Cross-Sectional Studies</topic><topic>Female</topic><topic>Humans</topic><topic>Hypertension - complications</topic><topic>Hypertension - mortality</topic><topic>Hypertension - physiopathology</topic><topic>Italy</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Risk Factors</topic><topic>Survival Rate</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cacciatore, Francesco</creatorcontrib><creatorcontrib>Abete, Pasquale</creatorcontrib><creatorcontrib>de Santis, Domenico</creatorcontrib><creatorcontrib>Longobardi, Giancarlo</creatorcontrib><creatorcontrib>Ferrara, Nicola</creatorcontrib><creatorcontrib>Rengo, Franco</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Social Sciences Premium Collection</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Science Database (Alumni Edition)</collection><collection>Social Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Social Science Premium Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest Psychology</collection><collection>Science Database</collection><collection>Social Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest Central (New)</collection><collection>ProQuest One Academic (New)</collection><collection>ProQuest Health & Medical Research Collection</collection><collection>ProQuest One Academic Middle East (New)</collection><collection>ProQuest Sociology & Social Sciences Collection</collection><collection>ProQuest One Health & Nursing</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Social Sciences</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>SIRS Editorial</collection><collection>MEDLINE - Academic</collection><jtitle>Gerontology (Basel)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cacciatore, Francesco</au><au>Abete, Pasquale</au><au>de Santis, Domenico</au><au>Longobardi, Giancarlo</au><au>Ferrara, Nicola</au><au>Rengo, Franco</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mortality and Blood Pressure in Elderly People with and without Cognitive Impairment</atitle><jtitle>Gerontology (Basel)</jtitle><addtitle>Gerontology</addtitle><date>2005-01</date><risdate>2005</risdate><volume>51</volume><issue>1</issue><spage>53</spage><epage>61</epage><pages>53-61</pages><issn>0304-324X</issn><eissn>1423-0003</eissn><coden>GERNDJ</coden><abstract>Background: Controversial data are available on the association between mortality, blood pressure and cognitive impairment in the elderly. Objective: To verify the role of blood pressure on mortality in an elderly population with and without cognitive impairment. Methods: A cross-sectional survey with a 6-year mortality evaluation was conducted in a region of southern Italy in elderly subjects with and without cognitive impairment. Subjects were divided into 4 groups on the basis of systolic, diastolic, mean and pulse blood pressure values. Results: Mortality shows a linear relationship with pulse blood pressure and a U-curve shape for diastolic blood pressure. This phenomenon was more evident in subjects with cognitive impairment showing the greatest risk of mortality at the lowest and highest levels of diastolic blood pressure. Conclusion: The study shows that mortality increases linearly with increasing blood pressure in the elderly. In contrast, mortality shows a U-shape curve for diastolic blood pressure; cognitively impaired patients with the lowest and highest diastolic blood pressures show the greatest relative risk of mortality.</abstract><cop>Basel, Switzerland</cop><pub>Karger</pub><pmid>15591757</pmid><doi>10.1159/000081436</doi><tpages>9</tpages></addata></record> |
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| subjects | Aged Aged, 80 and over Arterial hypertension. Arterial hypotension Biological and medical sciences Blood and lymphatic vessels Blood Pressure Cardiology. Vascular system Clinical manifestations. Epidemiology. Investigative techniques. Etiology Clinical Section Cognition Disorders - complications Cross-Sectional Studies Female Humans Hypertension - complications Hypertension - mortality Hypertension - physiopathology Italy Male Medical sciences Risk Factors Survival Rate |
| title | Mortality and Blood Pressure in Elderly People with and without Cognitive Impairment |
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