Comparative Evaluation of Thermodilution and Gated Blood Pool Method for Determination of Right Ventricular Ejection Fraction at Rest and during Exercise
Background: Since the development of a Swan-Ganz thermodilution ejection fraction catheter several studies have been published which compare this technique for obtaining right ventricular ejection fraction (RVEF TD ) with alternative methods. However, the reliability of RVEF TD measurements under ex...
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| Veröffentlicht in: | Cardiology 2001-01, Vol.95 (3), p.161-163 |
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| creator | Perings, Stefan M. Perings, Christian Kelm, Malte Strauer, Bodo E. |
| description | Background: Since the development of a Swan-Ganz thermodilution ejection fraction catheter several studies have been published which compare this technique for obtaining right ventricular ejection fraction (RVEF TD ) with alternative methods. However, the reliability of RVEF TD measurements under exercise conditions remains undetermined. Therefore, the aim of the present study was a comparative evaluation of RVEF TD with the established gated blood pool method (RVEF GBP ) under exercise conditions. Methods and Results: Twenty-two patients with different cardiac diseases underwent right heart catheterization, including RVEF TD and simultaneous RVEF GBP determination at rest and during supine bicycle exercise. Linear regression analysis showed a significant correlation between RVEF TD and RVEF GBP at rest (r = 0.73, p ≤ 0.0005) and during exercise (r = 0.74, p ≤ 0.0005). A Wilcoxon analysis showed a high probability of agreement of RVEF TD and RVEF GBP at rest and exercise (level of significance for error of the 0 hypothesis of 95.9/73.3%). Conclusion: The thermodilution ejection fraction catheter provides a useful device for reliable, repetitive and safe RVEF measurements, not only at rest but also under exercise conditions. This seems to be clinically important, because by it means RVEF, as a sensitive parameter of primary or secondary right ventricular dysfunction, can be determined in the course of standard right heart catheterization. |
| doi_str_mv | 10.1159/000047364 |
| format | Article |
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However, the reliability of RVEF TD measurements under exercise conditions remains undetermined. Therefore, the aim of the present study was a comparative evaluation of RVEF TD with the established gated blood pool method (RVEF GBP ) under exercise conditions. Methods and Results: Twenty-two patients with different cardiac diseases underwent right heart catheterization, including RVEF TD and simultaneous RVEF GBP determination at rest and during supine bicycle exercise. Linear regression analysis showed a significant correlation between RVEF TD and RVEF GBP at rest (r = 0.73, p ≤ 0.0005) and during exercise (r = 0.74, p ≤ 0.0005). A Wilcoxon analysis showed a high probability of agreement of RVEF TD and RVEF GBP at rest and exercise (level of significance for error of the 0 hypothesis of 95.9/73.3%). Conclusion: The thermodilution ejection fraction catheter provides a useful device for reliable, repetitive and safe RVEF measurements, not only at rest but also under exercise conditions. This seems to be clinically important, because by it means RVEF, as a sensitive parameter of primary or secondary right ventricular dysfunction, can be determined in the course of standard right heart catheterization.</description><identifier>ISSN: 0008-6312</identifier><identifier>EISSN: 1421-9751</identifier><identifier>DOI: 10.1159/000047364</identifier><identifier>PMID: 11474163</identifier><identifier>CODEN: CAGYAO</identifier><language>eng</language><publisher>Basel, Switzerland: Karger</publisher><subject>Adult ; Aged ; Biological and medical sciences ; Cardiac Catheterization ; Cardiovascular system ; Exercise Test ; Female ; Gated Blood-Pool Imaging ; Heart Diseases - diagnosis ; Heart Diseases - physiopathology ; Hemodynamics - physiology ; Humans ; Investigative techniques of hemodynamics ; Investigative techniques, diagnostic techniques (general aspects) ; Male ; Medical sciences ; Middle Aged ; Sensitivity and Specificity ; Stroke Volume - physiology ; Technical Note ; Thermodilution ; Ventricular Dysfunction, Right - diagnosis ; Ventricular Dysfunction, Right - physiopathology ; Ventricular Function, Right - physiology</subject><ispartof>Cardiology, 2001-01, Vol.95 (3), p.161-163</ispartof><rights>2001 S. Karger AG, Basel</rights><rights>2001 INIST-CNRS</rights><rights>Copyright 2001 S. Karger AG, Basel</rights><rights>Copyright (c) 2001 S. Karger AG, Basel</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c446t-275bc1cc24c74e5b26635b7bb4f1abc2d445d5722b7f7b04df9534db9de73b6e3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,2429,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1066426$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11474163$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Perings, Stefan M.</creatorcontrib><creatorcontrib>Perings, Christian</creatorcontrib><creatorcontrib>Kelm, Malte</creatorcontrib><creatorcontrib>Strauer, Bodo E.</creatorcontrib><title>Comparative Evaluation of Thermodilution and Gated Blood Pool Method for Determination of Right Ventricular Ejection Fraction at Rest and during Exercise</title><title>Cardiology</title><addtitle>Cardiology</addtitle><description>Background: Since the development of a Swan-Ganz thermodilution ejection fraction catheter several studies have been published which compare this technique for obtaining right ventricular ejection fraction (RVEF TD ) with alternative methods. However, the reliability of RVEF TD measurements under exercise conditions remains undetermined. Therefore, the aim of the present study was a comparative evaluation of RVEF TD with the established gated blood pool method (RVEF GBP ) under exercise conditions. Methods and Results: Twenty-two patients with different cardiac diseases underwent right heart catheterization, including RVEF TD and simultaneous RVEF GBP determination at rest and during supine bicycle exercise. Linear regression analysis showed a significant correlation between RVEF TD and RVEF GBP at rest (r = 0.73, p ≤ 0.0005) and during exercise (r = 0.74, p ≤ 0.0005). A Wilcoxon analysis showed a high probability of agreement of RVEF TD and RVEF GBP at rest and exercise (level of significance for error of the 0 hypothesis of 95.9/73.3%). Conclusion: The thermodilution ejection fraction catheter provides a useful device for reliable, repetitive and safe RVEF measurements, not only at rest but also under exercise conditions. This seems to be clinically important, because by it means RVEF, as a sensitive parameter of primary or secondary right ventricular dysfunction, can be determined in the course of standard right heart catheterization.</description><subject>Adult</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Cardiac Catheterization</subject><subject>Cardiovascular system</subject><subject>Exercise Test</subject><subject>Female</subject><subject>Gated Blood-Pool Imaging</subject><subject>Heart Diseases - diagnosis</subject><subject>Heart Diseases - physiopathology</subject><subject>Hemodynamics - physiology</subject><subject>Humans</subject><subject>Investigative techniques of hemodynamics</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Sensitivity and Specificity</subject><subject>Stroke Volume - physiology</subject><subject>Technical Note</subject><subject>Thermodilution</subject><subject>Ventricular Dysfunction, Right - diagnosis</subject><subject>Ventricular Dysfunction, Right - physiopathology</subject><subject>Ventricular Function, Right - physiology</subject><issn>0008-6312</issn><issn>1421-9751</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkV2L1DAUhoMo7rh64bUgQUTwotqT5mN6qbOzq7CiDKu3JR-nMx3bZkzaRX-K_9ZsZ5gVETY3eTnnyZs3OYQ8hfwNgCjf5mlxVUh-j8yAM8hKJeA-maXyPJMFsBPyKMbtRHH2kJwAJAGymJHfC9_tdNBDc410ea3bMUnfU1_Tqw2GzrumHaeK7h290AM6-r713tEv3rf0Ew6bpGsf6BkOiW_64_lVs94M9Bv2Q2js2OpAl1u0U_c86L3QA11hHCZzN4amX9PlTwy2ifiYPKh1G_HJYT8lX8-XV4sP2eXni4-Ld5eZ5VwOGVPCWLCWcas4CsOkLIRRxvAatLHMcS6cUIwZVSuTc1eXouDOlA5VYSQWp-TV3ncX_I8xham6JlpsW92jH2OlIC-4zOd3giwvQTFxNwhzYJBLlsAX_4BbP4Y-vbZiiksJUtxAr_eQDT7GgHW1C02nw68K8upm_NVx_Il9fjAcTYfuljzMOwEvD4COVrd10H36678cpeRM3gb7rsMaw7G_WJ1NF1U7Vyfo2X-hfZQ_IZrMUg</recordid><startdate>20010101</startdate><enddate>20010101</enddate><creator>Perings, Stefan M.</creator><creator>Perings, Christian</creator><creator>Kelm, Malte</creator><creator>Strauer, Bodo E.</creator><general>Karger</general><general>S. 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Perings, Christian ; Kelm, Malte ; Strauer, Bodo E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c446t-275bc1cc24c74e5b26635b7bb4f1abc2d445d5722b7f7b04df9534db9de73b6e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Cardiac Catheterization</topic><topic>Cardiovascular system</topic><topic>Exercise Test</topic><topic>Female</topic><topic>Gated Blood-Pool Imaging</topic><topic>Heart Diseases - diagnosis</topic><topic>Heart Diseases - physiopathology</topic><topic>Hemodynamics - physiology</topic><topic>Humans</topic><topic>Investigative techniques of hemodynamics</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Sensitivity and Specificity</topic><topic>Stroke Volume - physiology</topic><topic>Technical Note</topic><topic>Thermodilution</topic><topic>Ventricular Dysfunction, Right - diagnosis</topic><topic>Ventricular Dysfunction, Right - physiopathology</topic><topic>Ventricular Function, Right - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Perings, Stefan M.</creatorcontrib><creatorcontrib>Perings, Christian</creatorcontrib><creatorcontrib>Kelm, Malte</creatorcontrib><creatorcontrib>Strauer, Bodo E.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>Physical Education Index</collection><collection>MEDLINE - Academic</collection><jtitle>Cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Perings, Stefan M.</au><au>Perings, Christian</au><au>Kelm, Malte</au><au>Strauer, Bodo E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparative Evaluation of Thermodilution and Gated Blood Pool Method for Determination of Right Ventricular Ejection Fraction at Rest and during Exercise</atitle><jtitle>Cardiology</jtitle><addtitle>Cardiology</addtitle><date>2001-01-01</date><risdate>2001</risdate><volume>95</volume><issue>3</issue><spage>161</spage><epage>163</epage><pages>161-163</pages><issn>0008-6312</issn><eissn>1421-9751</eissn><coden>CAGYAO</coden><abstract>Background: Since the development of a Swan-Ganz thermodilution ejection fraction catheter several studies have been published which compare this technique for obtaining right ventricular ejection fraction (RVEF TD ) with alternative methods. However, the reliability of RVEF TD measurements under exercise conditions remains undetermined. Therefore, the aim of the present study was a comparative evaluation of RVEF TD with the established gated blood pool method (RVEF GBP ) under exercise conditions. Methods and Results: Twenty-two patients with different cardiac diseases underwent right heart catheterization, including RVEF TD and simultaneous RVEF GBP determination at rest and during supine bicycle exercise. Linear regression analysis showed a significant correlation between RVEF TD and RVEF GBP at rest (r = 0.73, p ≤ 0.0005) and during exercise (r = 0.74, p ≤ 0.0005). A Wilcoxon analysis showed a high probability of agreement of RVEF TD and RVEF GBP at rest and exercise (level of significance for error of the 0 hypothesis of 95.9/73.3%). Conclusion: The thermodilution ejection fraction catheter provides a useful device for reliable, repetitive and safe RVEF measurements, not only at rest but also under exercise conditions. This seems to be clinically important, because by it means RVEF, as a sensitive parameter of primary or secondary right ventricular dysfunction, can be determined in the course of standard right heart catheterization.</abstract><cop>Basel, Switzerland</cop><pub>Karger</pub><pmid>11474163</pmid><doi>10.1159/000047364</doi><tpages>3</tpages></addata></record> |
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| ispartof | Cardiology, 2001-01, Vol.95 (3), p.161-163 |
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| subjects | Adult Aged Biological and medical sciences Cardiac Catheterization Cardiovascular system Exercise Test Female Gated Blood-Pool Imaging Heart Diseases - diagnosis Heart Diseases - physiopathology Hemodynamics - physiology Humans Investigative techniques of hemodynamics Investigative techniques, diagnostic techniques (general aspects) Male Medical sciences Middle Aged Sensitivity and Specificity Stroke Volume - physiology Technical Note Thermodilution Ventricular Dysfunction, Right - diagnosis Ventricular Dysfunction, Right - physiopathology Ventricular Function, Right - physiology |
| title | Comparative Evaluation of Thermodilution and Gated Blood Pool Method for Determination of Right Ventricular Ejection Fraction at Rest and during Exercise |
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