Polymeric Micelles for Targeted Drug Delivery System
Targeted drug transport is becoming more and more popular for increasing the efficiency of interactions between a drug and a target. This method allows the drug concentration to be increased at a desired site and to block or strongly limit drug accumulation in healthy organs and tissues. Micelle-bas...
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| Veröffentlicht in: | Applied biochemistry and microbiology 2022-12, Vol.58 (6), p.726-737 |
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| container_title | Applied biochemistry and microbiology |
| container_volume | 58 |
| creator | Guliy, O. I. Staroverov, S. A. Fomin, A. S. Zhnichkova, E. G. Kozlov, S. V. Lovtsova, L. G. Dykman, L. A. |
| description | Targeted drug transport is becoming more and more popular for increasing the efficiency of interactions between a drug and a target. This method allows the drug concentration to be increased at a desired site and to block or strongly limit drug accumulation in healthy organs and tissues. Micelle-based nanopreparations can be considered as a system with unique characteristics compared to other nanocarriers, since the smaller size allows passive targeting of target organs (even poorly permeable ones) and efficient internalization by cells. Polymeric micelles are increasingly being used to create drug delivery systems. This paper presents a brief overview of the production of polymeric micelles, the release of the drug, and the possibility of their practical application. |
| doi_str_mv | 10.1134/S0003683822060059 |
| format | Article |
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| language | eng |
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| subjects | Biochemistry Biomedical and Life Sciences Drug delivery Drug delivery systems Internalization Life Sciences Medical Microbiology Micelles Microbiology Organs |
| title | Polymeric Micelles for Targeted Drug Delivery System |
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