A solvent controlled three-component reaction of diazo compounds for the synthesis of hydrazone compounds under Brønsted acid catalysis

A solvent controlled three-component reaction of diazo compounds for the synthesis of hydrazone compounds under Brønsted acid catalysis

A novel Brønsted acid catalyzed three-component reaction of diazo compounds has been achieved from α-diazo ester, N -aminophthalimide and a solvent. An important feature of the method is that different products can be prepared selectively by modulating the reaction solvent. The reaction allows the s...

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Veröffentlicht in:New journal of chemistry 2022-12, Vol.46 (47), p.22513-22517
Hauptverfasser: He, Hangli, Yan, Zhewei, Wang, Junyong, Yan, Qiongjiao, Wang, Wei, Wang, Haifeng, Chen, Fener
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Chemical synthesis
Hydrazones
Solvents
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container_end_page 22517
container_issue 47
container_start_page 22513
container_title New journal of chemistry
container_volume 46
creator He, Hangli
Yan, Zhewei
Wang, Junyong
Yan, Qiongjiao
Wang, Wei
Wang, Haifeng
Chen, Fener
description A novel Brønsted acid catalyzed three-component reaction of diazo compounds has been achieved from α-diazo ester, N -aminophthalimide and a solvent. An important feature of the method is that different products can be prepared selectively by modulating the reaction solvent. The reaction allows the synthesis of various amide hydrazone and α-hydroxyhydrazone products in moderate to good yield.
doi_str_mv 10.1039/D2NJ04983J
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source Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection
subjects Chemical synthesis
Hydrazones
Solvents
title A solvent controlled three-component reaction of diazo compounds for the synthesis of hydrazone compounds under Brønsted acid catalysis
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