Molecular Dynamics Simulation Study on the Effect of Oxali-Palladium as a Catalytic Inhibitor of Human Topoisomerase IIα

Among the many anticancer agents targeting topoisomerase IIα enzyme, palladium (II) analogues have gained in popularity as a promising enzyme inhibitor. In this article, molecular docking method and molecular dynamics (MD) simulations were employed to study the mechanism through which oxali-palladiu...

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