A prodrug nanoplatform via esterification of STING agonist and IDO inhibitor for synergistic cancer immunotherapy

Cancer immunotherapy has made significant progress in the last few decades, revolutionizing oncology. However, low patient response rates and potential immune-related adverse events continue to be major clinical challenges. Cancer nanomedicine, by virtue of its regulated delivery and modular flexibi...

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Veröffentlicht in:	Nano research 2022-10, Vol.15 (10), p.9215-9222
Hauptverfasser:	Syeda, Madiha Zahra, Hong, Tu, Zhang, Min, Han, Yanfei, Zhu, Xiaoling, Ying, Songmin, Tang, Longguang
Format:	Artikel
Sprache:	eng
Schlagworte:	Agonists Anticancer properties Antitumor activity Antitumor agents Atomic/Molecular Structure and Spectra Bioavailability Biocompatibility Biomedicine Biotechnology Cancer Cancer immunotherapy Chemistry and Materials Science Clinical trials Condensed Matter Physics Dioxygenase Esterification Growth inhibition Immune response Immune system Immunotherapy Inhibitors Interferon Light scattering Mass spectrometry Mass spectroscopy Materials Science Nanoparticles Nanotechnology Photon correlation spectroscopy Prodrugs Research Article Side effects Stimulators Synthesis Toxicity Transmission electron microscopy Tumor microenvironment Tumors
Online-Zugang:	Volltext
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