Aptamer Functionalized ZnO Thin-Film Transistor Based Multiplexed Detection of Pb and E. Coli in Water
In this work, we demonstrate the multiplexed detection platform to sense lead (Pb2+) and Escherichia coli in water using zinc oxide (ZnO) thin-film transistors (TFTs). Low-voltage ZnO TFTs fabricated by physical vapor deposition were functionalized with (3-Aminopropyl)triethoxysilane (APTES)–glutara...
Gespeichert in:
| Veröffentlicht in: | IEEE sensors journal 2022-11, Vol.22 (21), p.21209-21217 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 21217 |
|---|---|
| container_issue | 21 |
| container_start_page | 21209 |
| container_title | IEEE sensors journal |
| container_volume | 22 |
| creator | Honnali, Sanath Kumar Srinivasa Raghavan, Vikram Ashwath, Roopa Saravanavel, Ganapathy Gunasekhar, K. R. Sambandan, Sanjiv Gorthi, Sai Siva O'Driscoll, Benjamin Jenkins, David |
| description | In this work, we demonstrate the multiplexed detection platform to sense lead (Pb2+) and Escherichia coli in water using zinc oxide (ZnO) thin-film transistors (TFTs). Low-voltage ZnO TFTs fabricated by physical vapor deposition were functionalized with (3-Aminopropyl)triethoxysilane (APTES)–glutaraldehyde (GLU) molecules. TFTs with such functionalized ZnO surfaces showed good sensitivity and high specificity to the targets with a detection limit of 27 nM and [Formula Omitted] colony forming unit per mL (cfu/mL) for Pb2+ and E. coli, respectively, with the TFT flat-band voltage ([Formula Omitted]) and, hence, the TFT transconductance, being dependent on the target concentration. The direct integration of the sensing with the TFT and associated integrated circuits promises high-density sensor arrays. |
| doi_str_mv | 10.1109/JSEN.2022.3207467 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_2731242780</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2731242780</sourcerecordid><originalsourceid>FETCH-LOGICAL-c2317-b35236b8648240b4ede72b92c9d06924d03b8170d298bf32ec3191b5edcdf3df3</originalsourceid><addsrcrecordid>eNotkF9LwzAUxYMoOKcfwLeAz63JTdq0j3Nu_mE6wYniS0iaFDO6tiYtqJ_e1gkX7oF7zoXzQ-ickphSkl_ePy8eYyAAMQMieCoO0IQmSRZRwbPDUTMScSbejtFJCFtCaC4SMUHlrO3Uznq87Ouic02tKvdjDX6v13jz4epo6aod3nhVBxe6xuMrFYbzQ191rq3s16CvbWf_orgp8ZPGqjZ4EeN5UznsavyqOutP0VGpqmDP_vcUvSwXm_lttFrf3M1nq6gARkWkWQIs1VnKM-BEc2usAJ1DkRuS5sANYTqjghjIM10ysAWjOdWJNYUp2TBTdLH_2_rms7ehk9um90OpIEEwChxERgYX3bsK34TgbSlb73bKf0tK5IhTjjjliFP-42S_MCZnQg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2731242780</pqid></control><display><type>article</type><title>Aptamer Functionalized ZnO Thin-Film Transistor Based Multiplexed Detection of Pb and E. Coli in Water</title><source>IEEE Electronic Library (IEL)</source><creator>Honnali, Sanath Kumar ; Srinivasa Raghavan, Vikram ; Ashwath, Roopa ; Saravanavel, Ganapathy ; Gunasekhar, K. R. ; Sambandan, Sanjiv ; Gorthi, Sai Siva ; O'Driscoll, Benjamin ; Jenkins, David</creator><creatorcontrib>Honnali, Sanath Kumar ; Srinivasa Raghavan, Vikram ; Ashwath, Roopa ; Saravanavel, Ganapathy ; Gunasekhar, K. R. ; Sambandan, Sanjiv ; Gorthi, Sai Siva ; O'Driscoll, Benjamin ; Jenkins, David</creatorcontrib><description>In this work, we demonstrate the multiplexed detection platform to sense lead (Pb2+) and Escherichia coli in water using zinc oxide (ZnO) thin-film transistors (TFTs). Low-voltage ZnO TFTs fabricated by physical vapor deposition were functionalized with (3-Aminopropyl)triethoxysilane (APTES)–glutaraldehyde (GLU) molecules. TFTs with such functionalized ZnO surfaces showed good sensitivity and high specificity to the targets with a detection limit of 27 nM and [Formula Omitted] colony forming unit per mL (cfu/mL) for Pb2+ and E. coli, respectively, with the TFT flat-band voltage ([Formula Omitted]) and, hence, the TFT transconductance, being dependent on the target concentration. The direct integration of the sensing with the TFT and associated integrated circuits promises high-density sensor arrays.</description><identifier>ISSN: 1530-437X</identifier><identifier>EISSN: 1558-1748</identifier><identifier>DOI: 10.1109/JSEN.2022.3207467</identifier><language>eng</language><publisher>New York: The Institute of Electrical and Electronics Engineers, Inc. (IEEE)</publisher><subject>Aminopropyltriethoxysilane ; E coli ; Electric potential ; Integrated circuits ; Multiplexing ; Physical vapor deposition ; Semiconductor devices ; Sensor arrays ; Target detection ; Thin film transistors ; Transconductance ; Voltage ; Zinc oxide</subject><ispartof>IEEE sensors journal, 2022-11, Vol.22 (21), p.21209-21217</ispartof><rights>Copyright The Institute of Electrical and Electronics Engineers, Inc. (IEEE) 2022</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2317-b35236b8648240b4ede72b92c9d06924d03b8170d298bf32ec3191b5edcdf3df3</citedby><orcidid>0000-0002-6996-9763 ; 0000-0002-7242-1889 ; 0000-0001-5146-8381 ; 0000-0001-6215-2454</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids></links><search><creatorcontrib>Honnali, Sanath Kumar</creatorcontrib><creatorcontrib>Srinivasa Raghavan, Vikram</creatorcontrib><creatorcontrib>Ashwath, Roopa</creatorcontrib><creatorcontrib>Saravanavel, Ganapathy</creatorcontrib><creatorcontrib>Gunasekhar, K. R.</creatorcontrib><creatorcontrib>Sambandan, Sanjiv</creatorcontrib><creatorcontrib>Gorthi, Sai Siva</creatorcontrib><creatorcontrib>O'Driscoll, Benjamin</creatorcontrib><creatorcontrib>Jenkins, David</creatorcontrib><title>Aptamer Functionalized ZnO Thin-Film Transistor Based Multiplexed Detection of Pb and E. Coli in Water</title><title>IEEE sensors journal</title><description>In this work, we demonstrate the multiplexed detection platform to sense lead (Pb2+) and Escherichia coli in water using zinc oxide (ZnO) thin-film transistors (TFTs). Low-voltage ZnO TFTs fabricated by physical vapor deposition were functionalized with (3-Aminopropyl)triethoxysilane (APTES)–glutaraldehyde (GLU) molecules. TFTs with such functionalized ZnO surfaces showed good sensitivity and high specificity to the targets with a detection limit of 27 nM and [Formula Omitted] colony forming unit per mL (cfu/mL) for Pb2+ and E. coli, respectively, with the TFT flat-band voltage ([Formula Omitted]) and, hence, the TFT transconductance, being dependent on the target concentration. The direct integration of the sensing with the TFT and associated integrated circuits promises high-density sensor arrays.</description><subject>Aminopropyltriethoxysilane</subject><subject>E coli</subject><subject>Electric potential</subject><subject>Integrated circuits</subject><subject>Multiplexing</subject><subject>Physical vapor deposition</subject><subject>Semiconductor devices</subject><subject>Sensor arrays</subject><subject>Target detection</subject><subject>Thin film transistors</subject><subject>Transconductance</subject><subject>Voltage</subject><subject>Zinc oxide</subject><issn>1530-437X</issn><issn>1558-1748</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNotkF9LwzAUxYMoOKcfwLeAz63JTdq0j3Nu_mE6wYniS0iaFDO6tiYtqJ_e1gkX7oF7zoXzQ-ickphSkl_ePy8eYyAAMQMieCoO0IQmSRZRwbPDUTMScSbejtFJCFtCaC4SMUHlrO3Uznq87Ouic02tKvdjDX6v13jz4epo6aod3nhVBxe6xuMrFYbzQ191rq3s16CvbWf_orgp8ZPGqjZ4EeN5UznsavyqOutP0VGpqmDP_vcUvSwXm_lttFrf3M1nq6gARkWkWQIs1VnKM-BEc2usAJ1DkRuS5sANYTqjghjIM10ysAWjOdWJNYUp2TBTdLH_2_rms7ehk9um90OpIEEwChxERgYX3bsK34TgbSlb73bKf0tK5IhTjjjliFP-42S_MCZnQg</recordid><startdate>20221101</startdate><enddate>20221101</enddate><creator>Honnali, Sanath Kumar</creator><creator>Srinivasa Raghavan, Vikram</creator><creator>Ashwath, Roopa</creator><creator>Saravanavel, Ganapathy</creator><creator>Gunasekhar, K. R.</creator><creator>Sambandan, Sanjiv</creator><creator>Gorthi, Sai Siva</creator><creator>O'Driscoll, Benjamin</creator><creator>Jenkins, David</creator><general>The Institute of Electrical and Electronics Engineers, Inc. (IEEE)</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7SP</scope><scope>7U5</scope><scope>8FD</scope><scope>L7M</scope><orcidid>https://orcid.org/0000-0002-6996-9763</orcidid><orcidid>https://orcid.org/0000-0002-7242-1889</orcidid><orcidid>https://orcid.org/0000-0001-5146-8381</orcidid><orcidid>https://orcid.org/0000-0001-6215-2454</orcidid></search><sort><creationdate>20221101</creationdate><title>Aptamer Functionalized ZnO Thin-Film Transistor Based Multiplexed Detection of Pb and E. Coli in Water</title><author>Honnali, Sanath Kumar ; Srinivasa Raghavan, Vikram ; Ashwath, Roopa ; Saravanavel, Ganapathy ; Gunasekhar, K. R. ; Sambandan, Sanjiv ; Gorthi, Sai Siva ; O'Driscoll, Benjamin ; Jenkins, David</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2317-b35236b8648240b4ede72b92c9d06924d03b8170d298bf32ec3191b5edcdf3df3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Aminopropyltriethoxysilane</topic><topic>E coli</topic><topic>Electric potential</topic><topic>Integrated circuits</topic><topic>Multiplexing</topic><topic>Physical vapor deposition</topic><topic>Semiconductor devices</topic><topic>Sensor arrays</topic><topic>Target detection</topic><topic>Thin film transistors</topic><topic>Transconductance</topic><topic>Voltage</topic><topic>Zinc oxide</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Honnali, Sanath Kumar</creatorcontrib><creatorcontrib>Srinivasa Raghavan, Vikram</creatorcontrib><creatorcontrib>Ashwath, Roopa</creatorcontrib><creatorcontrib>Saravanavel, Ganapathy</creatorcontrib><creatorcontrib>Gunasekhar, K. R.</creatorcontrib><creatorcontrib>Sambandan, Sanjiv</creatorcontrib><creatorcontrib>Gorthi, Sai Siva</creatorcontrib><creatorcontrib>O'Driscoll, Benjamin</creatorcontrib><creatorcontrib>Jenkins, David</creatorcontrib><collection>CrossRef</collection><collection>Electronics & Communications Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Technology Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><jtitle>IEEE sensors journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Honnali, Sanath Kumar</au><au>Srinivasa Raghavan, Vikram</au><au>Ashwath, Roopa</au><au>Saravanavel, Ganapathy</au><au>Gunasekhar, K. R.</au><au>Sambandan, Sanjiv</au><au>Gorthi, Sai Siva</au><au>O'Driscoll, Benjamin</au><au>Jenkins, David</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Aptamer Functionalized ZnO Thin-Film Transistor Based Multiplexed Detection of Pb and E. Coli in Water</atitle><jtitle>IEEE sensors journal</jtitle><date>2022-11-01</date><risdate>2022</risdate><volume>22</volume><issue>21</issue><spage>21209</spage><epage>21217</epage><pages>21209-21217</pages><issn>1530-437X</issn><eissn>1558-1748</eissn><abstract>In this work, we demonstrate the multiplexed detection platform to sense lead (Pb2+) and Escherichia coli in water using zinc oxide (ZnO) thin-film transistors (TFTs). Low-voltage ZnO TFTs fabricated by physical vapor deposition were functionalized with (3-Aminopropyl)triethoxysilane (APTES)–glutaraldehyde (GLU) molecules. TFTs with such functionalized ZnO surfaces showed good sensitivity and high specificity to the targets with a detection limit of 27 nM and [Formula Omitted] colony forming unit per mL (cfu/mL) for Pb2+ and E. coli, respectively, with the TFT flat-band voltage ([Formula Omitted]) and, hence, the TFT transconductance, being dependent on the target concentration. The direct integration of the sensing with the TFT and associated integrated circuits promises high-density sensor arrays.</abstract><cop>New York</cop><pub>The Institute of Electrical and Electronics Engineers, Inc. (IEEE)</pub><doi>10.1109/JSEN.2022.3207467</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0002-6996-9763</orcidid><orcidid>https://orcid.org/0000-0002-7242-1889</orcidid><orcidid>https://orcid.org/0000-0001-5146-8381</orcidid><orcidid>https://orcid.org/0000-0001-6215-2454</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1530-437X |
| ispartof | IEEE sensors journal, 2022-11, Vol.22 (21), p.21209-21217 |
| issn | 1530-437X 1558-1748 |
| language | eng |
| recordid | cdi_proquest_journals_2731242780 |
| source | IEEE Electronic Library (IEL) |
| subjects | Aminopropyltriethoxysilane E coli Electric potential Integrated circuits Multiplexing Physical vapor deposition Semiconductor devices Sensor arrays Target detection Thin film transistors Transconductance Voltage Zinc oxide |
| title | Aptamer Functionalized ZnO Thin-Film Transistor Based Multiplexed Detection of Pb and E. Coli in Water |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-22T07%3A52%3A00IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Aptamer%20Functionalized%20ZnO%20Thin-Film%20Transistor%20Based%20Multiplexed%20Detection%20of%20Pb%20and%20E.%20Coli%20in%20Water&rft.jtitle=IEEE%20sensors%20journal&rft.au=Honnali,%20Sanath%20Kumar&rft.date=2022-11-01&rft.volume=22&rft.issue=21&rft.spage=21209&rft.epage=21217&rft.pages=21209-21217&rft.issn=1530-437X&rft.eissn=1558-1748&rft_id=info:doi/10.1109/JSEN.2022.3207467&rft_dat=%3Cproquest_cross%3E2731242780%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2731242780&rft_id=info:pmid/&rfr_iscdi=true |