Intracytoplasmic sperm injection with fresh versus cryopreserved testicular sperm in azoospermic patients
Background The purpose of this study is to compare the outcome of intracytoplasmic sperm injection (ICSI) using fresh sperm versus frozen-thawed sperm in both obstructed and non-obstructed azoospermias. This retrospective study included 159 ICSI cycles from 126 couples. In 91 obstructed azoospermia...
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| Veröffentlicht in: | Middle East Fertility Society Journal 2019-12, Vol.24 (1), p.1-5, Article 11 |
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| description | Background
The purpose of this study is to compare the outcome of intracytoplasmic sperm injection (ICSI) using fresh sperm versus frozen-thawed sperm in both obstructed and non-obstructed azoospermias. This retrospective study included 159 ICSI cycles from 126 couples. In 91 obstructed azoospermia cases, 66 cycles were treated with fresh testicular sperm and 25 cycles were treated with frozen-thawed testicular samples. In 68 non-obstructed azoospermia cases, 32 cycles were treated with fresh testicular sperm and 36 cycles were treated with frozen-thawed testicular sperm, and the main measure and outcomes calculated are fertilization rate, clinical pregnancy, and live birth rate.
Results
In case of obstructed azoospermia, there were no statistically significant differences between fresh sperm and frozen-thawed testicular sperm used for ICSI regarding fertilization rate, clinical pregnancy rate, and live birth rate as shown (57%, 47%, 0.093
p
value; 23.7%, 17.4%, 0.54
p
value; and 11.9%, 8.7%, 0.68
p
value, respectively). Non-obstructed azoospermia cases also show no significant differences in fertilization rate (37%, 36%, 0.91
p
value), clinical pregnancy rate (20%, 14.3%, 0.58
p
value), and live birth rate (4%, 3.6%, 0.93
p
value).
Conclusion
Cryopreservation of testicular sperm is reliable if carried out before ovulation induction especially in cases with non-obstructive azoospermia |
| doi_str_mv | 10.1186/s43043-019-0010-1 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_doaj_</sourceid><recordid>TN_cdi_proquest_journals_2729533313</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A680137630</galeid><doaj_id>oai_doaj_org_article_a6592d8e787a480aa73962cadebe42e7</doaj_id><sourcerecordid>A680137630</sourcerecordid><originalsourceid>FETCH-LOGICAL-c492t-a88258d67849d1f0dc5210597b0386ec76e54c4694000897051ed3ceb8fe45323</originalsourceid><addsrcrecordid>eNp1UctqHDEQHEIMcex8QG4DPo_Teo2kozF5LBhySc6iV9Oz1rI7Gktah83XR-sJdgLJSVJRVaruapr3DK4ZM_2HLAVI0QGzHQCDjr1qzjlY6ARX7PUf9zfN25y3AMJwAedNWE0loT-WOO8w74Nv80xp34ZpS76EOLU_Qrlvx0T5vn2klA-59ekY5wpQeqShLZRL8Icdpmdpiz9jfHpUvxlLoKnky-ZsxF2md7_Pi-b7p4_fbr90d18_r25v7jovLS8dGsOVGXptpB3YCINXnIGyel0j9-R1T0p62VsJAMZqUIwG4WltRpJKcHHRrBbfIeLWzSnsMR1dxOCegJg2DlNNvCOHvbJ8MKSNRmkAUQvbc48DrUly0tXravGaU3w41EHdNh7SVOM7rrlVQggmXlgbrKZhGuNppfuQvbvpDTChewGVdf0PFp5-q2uKE42h4n8J2CLwKeacaHwehoE7le6W0l0t3Z1Kd6xq-KLJlTttKL0E_r_oF_czrqc</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2729533313</pqid></control><display><type>article</type><title>Intracytoplasmic sperm injection with fresh versus cryopreserved testicular sperm in azoospermic patients</title><source>DOAJ Directory of Open Access Journals</source><source>SpringerNature Journals</source><creator>M. Falah, Kani</creator><creatorcontrib>M. Falah, Kani</creatorcontrib><description>Background
The purpose of this study is to compare the outcome of intracytoplasmic sperm injection (ICSI) using fresh sperm versus frozen-thawed sperm in both obstructed and non-obstructed azoospermias. This retrospective study included 159 ICSI cycles from 126 couples. In 91 obstructed azoospermia cases, 66 cycles were treated with fresh testicular sperm and 25 cycles were treated with frozen-thawed testicular samples. In 68 non-obstructed azoospermia cases, 32 cycles were treated with fresh testicular sperm and 36 cycles were treated with frozen-thawed testicular sperm, and the main measure and outcomes calculated are fertilization rate, clinical pregnancy, and live birth rate.
Results
In case of obstructed azoospermia, there were no statistically significant differences between fresh sperm and frozen-thawed testicular sperm used for ICSI regarding fertilization rate, clinical pregnancy rate, and live birth rate as shown (57%, 47%, 0.093
p
value; 23.7%, 17.4%, 0.54
p
value; and 11.9%, 8.7%, 0.68
p
value, respectively). Non-obstructed azoospermia cases also show no significant differences in fertilization rate (37%, 36%, 0.91
p
value), clinical pregnancy rate (20%, 14.3%, 0.58
p
value), and live birth rate (4%, 3.6%, 0.93
p
value).
Conclusion
Cryopreservation of testicular sperm is reliable if carried out before ovulation induction especially in cases with non-obstructive azoospermia</description><identifier>ISSN: 2090-3251</identifier><identifier>ISSN: 1110-5690</identifier><identifier>EISSN: 2090-3251</identifier><identifier>DOI: 10.1186/s43043-019-0010-1</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Embryos ; Fertility ; Fresh testicular sperm ; Frozen-thawed testicular sperm ; ICSI ; Infertility ; Local anesthesia ; Medical colleges ; Medicine ; Medicine & Public Health ; Nitrogen ; Non-obstructive azoospermia ; Obstructive azoospermia ; Ovaries ; Pregnancy ; Sperm ; Spermatogenesis ; Spermatozoa ; Ultrasonic imaging</subject><ispartof>Middle East Fertility Society Journal, 2019-12, Vol.24 (1), p.1-5, Article 11</ispartof><rights>The Author(s) 2019</rights><rights>COPYRIGHT 2019 Springer</rights><rights>The Author(s) 2019. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c492t-a88258d67849d1f0dc5210597b0386ec76e54c4694000897051ed3ceb8fe45323</citedby><cites>FETCH-LOGICAL-c492t-a88258d67849d1f0dc5210597b0386ec76e54c4694000897051ed3ceb8fe45323</cites><orcidid>0000-0002-7977-3238</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,864,27924,27925</link.rule.ids></links><search><creatorcontrib>M. Falah, Kani</creatorcontrib><title>Intracytoplasmic sperm injection with fresh versus cryopreserved testicular sperm in azoospermic patients</title><title>Middle East Fertility Society Journal</title><addtitle>Middle East Fertil Soc J</addtitle><description>Background
The purpose of this study is to compare the outcome of intracytoplasmic sperm injection (ICSI) using fresh sperm versus frozen-thawed sperm in both obstructed and non-obstructed azoospermias. This retrospective study included 159 ICSI cycles from 126 couples. In 91 obstructed azoospermia cases, 66 cycles were treated with fresh testicular sperm and 25 cycles were treated with frozen-thawed testicular samples. In 68 non-obstructed azoospermia cases, 32 cycles were treated with fresh testicular sperm and 36 cycles were treated with frozen-thawed testicular sperm, and the main measure and outcomes calculated are fertilization rate, clinical pregnancy, and live birth rate.
Results
In case of obstructed azoospermia, there were no statistically significant differences between fresh sperm and frozen-thawed testicular sperm used for ICSI regarding fertilization rate, clinical pregnancy rate, and live birth rate as shown (57%, 47%, 0.093
p
value; 23.7%, 17.4%, 0.54
p
value; and 11.9%, 8.7%, 0.68
p
value, respectively). Non-obstructed azoospermia cases also show no significant differences in fertilization rate (37%, 36%, 0.91
p
value), clinical pregnancy rate (20%, 14.3%, 0.58
p
value), and live birth rate (4%, 3.6%, 0.93
p
value).
Conclusion
Cryopreservation of testicular sperm is reliable if carried out before ovulation induction especially in cases with non-obstructive azoospermia</description><subject>Embryos</subject><subject>Fertility</subject><subject>Fresh testicular sperm</subject><subject>Frozen-thawed testicular sperm</subject><subject>ICSI</subject><subject>Infertility</subject><subject>Local anesthesia</subject><subject>Medical colleges</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Nitrogen</subject><subject>Non-obstructive azoospermia</subject><subject>Obstructive azoospermia</subject><subject>Ovaries</subject><subject>Pregnancy</subject><subject>Sperm</subject><subject>Spermatogenesis</subject><subject>Spermatozoa</subject><subject>Ultrasonic imaging</subject><issn>2090-3251</issn><issn>1110-5690</issn><issn>2090-3251</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>DOA</sourceid><recordid>eNp1UctqHDEQHEIMcex8QG4DPo_Teo2kozF5LBhySc6iV9Oz1rI7Gktah83XR-sJdgLJSVJRVaruapr3DK4ZM_2HLAVI0QGzHQCDjr1qzjlY6ARX7PUf9zfN25y3AMJwAedNWE0loT-WOO8w74Nv80xp34ZpS76EOLU_Qrlvx0T5vn2klA-59ekY5wpQeqShLZRL8Icdpmdpiz9jfHpUvxlLoKnky-ZsxF2md7_Pi-b7p4_fbr90d18_r25v7jovLS8dGsOVGXptpB3YCINXnIGyel0j9-R1T0p62VsJAMZqUIwG4WltRpJKcHHRrBbfIeLWzSnsMR1dxOCegJg2DlNNvCOHvbJ8MKSNRmkAUQvbc48DrUly0tXravGaU3w41EHdNh7SVOM7rrlVQggmXlgbrKZhGuNppfuQvbvpDTChewGVdf0PFp5-q2uKE42h4n8J2CLwKeacaHwehoE7le6W0l0t3Z1Kd6xq-KLJlTttKL0E_r_oF_czrqc</recordid><startdate>20191221</startdate><enddate>20191221</enddate><creator>M. Falah, Kani</creator><general>Springer Berlin Heidelberg</general><general>Springer</general><general>Springer Nature B.V</general><general>SpringerOpen</general><scope>C6C</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-7977-3238</orcidid></search><sort><creationdate>20191221</creationdate><title>Intracytoplasmic sperm injection with fresh versus cryopreserved testicular sperm in azoospermic patients</title><author>M. Falah, Kani</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c492t-a88258d67849d1f0dc5210597b0386ec76e54c4694000897051ed3ceb8fe45323</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Embryos</topic><topic>Fertility</topic><topic>Fresh testicular sperm</topic><topic>Frozen-thawed testicular sperm</topic><topic>ICSI</topic><topic>Infertility</topic><topic>Local anesthesia</topic><topic>Medical colleges</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Nitrogen</topic><topic>Non-obstructive azoospermia</topic><topic>Obstructive azoospermia</topic><topic>Ovaries</topic><topic>Pregnancy</topic><topic>Sperm</topic><topic>Spermatogenesis</topic><topic>Spermatozoa</topic><topic>Ultrasonic imaging</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>M. Falah, Kani</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Middle East Fertility Society Journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>M. Falah, Kani</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Intracytoplasmic sperm injection with fresh versus cryopreserved testicular sperm in azoospermic patients</atitle><jtitle>Middle East Fertility Society Journal</jtitle><stitle>Middle East Fertil Soc J</stitle><date>2019-12-21</date><risdate>2019</risdate><volume>24</volume><issue>1</issue><spage>1</spage><epage>5</epage><pages>1-5</pages><artnum>11</artnum><issn>2090-3251</issn><issn>1110-5690</issn><eissn>2090-3251</eissn><abstract>Background
The purpose of this study is to compare the outcome of intracytoplasmic sperm injection (ICSI) using fresh sperm versus frozen-thawed sperm in both obstructed and non-obstructed azoospermias. This retrospective study included 159 ICSI cycles from 126 couples. In 91 obstructed azoospermia cases, 66 cycles were treated with fresh testicular sperm and 25 cycles were treated with frozen-thawed testicular samples. In 68 non-obstructed azoospermia cases, 32 cycles were treated with fresh testicular sperm and 36 cycles were treated with frozen-thawed testicular sperm, and the main measure and outcomes calculated are fertilization rate, clinical pregnancy, and live birth rate.
Results
In case of obstructed azoospermia, there were no statistically significant differences between fresh sperm and frozen-thawed testicular sperm used for ICSI regarding fertilization rate, clinical pregnancy rate, and live birth rate as shown (57%, 47%, 0.093
p
value; 23.7%, 17.4%, 0.54
p
value; and 11.9%, 8.7%, 0.68
p
value, respectively). Non-obstructed azoospermia cases also show no significant differences in fertilization rate (37%, 36%, 0.91
p
value), clinical pregnancy rate (20%, 14.3%, 0.58
p
value), and live birth rate (4%, 3.6%, 0.93
p
value).
Conclusion
Cryopreservation of testicular sperm is reliable if carried out before ovulation induction especially in cases with non-obstructive azoospermia</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><doi>10.1186/s43043-019-0010-1</doi><tpages>5</tpages><orcidid>https://orcid.org/0000-0002-7977-3238</orcidid><oa>free_for_read</oa></addata></record> |
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| issn | 2090-3251 1110-5690 2090-3251 |
| language | eng |
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| source | DOAJ Directory of Open Access Journals; SpringerNature Journals |
| subjects | Embryos Fertility Fresh testicular sperm Frozen-thawed testicular sperm ICSI Infertility Local anesthesia Medical colleges Medicine Medicine & Public Health Nitrogen Non-obstructive azoospermia Obstructive azoospermia Ovaries Pregnancy Sperm Spermatogenesis Spermatozoa Ultrasonic imaging |
| title | Intracytoplasmic sperm injection with fresh versus cryopreserved testicular sperm in azoospermic patients |
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