Atypical cartilage in type II germ cell tumors of the mediastinum show significantly different patterns of IDH1/2 mutations from conventional chondrosarcoma

Neoplastic cartilage is a common component of teratomas in type II germ cell tumors. Although IDH1/2 mutations have been well-described in somatic cartilaginous tumors, ranging from benign enchondromas to highly aggressive dedifferentiated chondrosarcomas, the presence of IDH1/2 mutations in cartila...

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Veröffentlicht in:Modern pathology 2022-11, Vol.35 (11), p.1636-1643
Hauptverfasser: Warmke, Laura M., Cheng, Liang, Sperling, R. Matthew, Sen, Joyashree D., Ulbright, Thomas M.
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Sprache:eng
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