ASIA syndrome with severe lupus – A case report
The autoimmune/inflammatory syndrome induced by adjuvants (ASIA), also known as Shoenfeld’s syndrome, encompasses several autoimmune conditions/phenomena that are triggered following the exposure to materials with an adjuvant activity known to augment an antigen-driven immune response. In some inher...
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| Veröffentlicht in: | Lupus 2022-10, Vol.31 (12), p.1532-1535 |
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| creator | Mir, Tajamul H Khan, Ajaz K Parvaiz, M Omar Rath, Prasan D Sharma, Alok |
| description | The autoimmune/inflammatory syndrome induced by adjuvants (ASIA), also known as Shoenfeld’s syndrome, encompasses several autoimmune conditions/phenomena that are triggered following the exposure to materials with an adjuvant activity known to augment an antigen-driven immune response. In some inherently vulnerable patients, they act as second hits to trigger or unmask an autoimmune disorder which ranges from generalized non-specific constitutional symptoms, and autoantibody production, to a new onset, of a fully-fledged autoimmune syndrome. In this manuscript, we present a case of a 37-year-old lady who developed systemic lupus erythematosus characterized by mucocutaneous, musculoskeletal, hematological neurological, and renal involvement a few years after silicone breast implants. |
| doi_str_mv | 10.1177/09612033221124424 |
| format | Article |
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| subjects | Adjuvants Adjuvants, Immunologic - adverse effects Adult Autoantibodies Autoimmune Diseases Breast Implants Case reports Female Humans Immune response Inflammation Lupus Lupus Erythematosus, Systemic - complications Lupus Erythematosus, Systemic - diagnosis Silicones Silicones - adverse effects Syndrome Systemic lupus erythematosus |
| title | ASIA syndrome with severe lupus – A case report |
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