P66 Risk factors for post-transplant diabetes mellitus in liver transplant recipients: A Systematic review and Meta-analysis

BackgroundPost-transplant diabetes mellitus (PTDM) is one of the most common metabolic complications following liver transplant (LT) that reduces graft and recipient overall survival. An accurate and detailed understanding of PTDM related risk factors after LT is critical for improving patient outco...

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Veröffentlicht in:Gut 2022-09, Vol.71 (Suppl 3), p.A79-A81
Hauptverfasser: Tariq, Muhammad Ali, Amin, Hamza, Ahmed, Bilal
Format: Artikel
Sprache:eng
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Zusammenfassung:BackgroundPost-transplant diabetes mellitus (PTDM) is one of the most common metabolic complications following liver transplant (LT) that reduces graft and recipient overall survival. An accurate and detailed understanding of PTDM related risk factors after LT is critical for improving patient outcomes and preventing PTDM incidences. Therefore, we aimed to conduct a meta-analysis to identify risk factors for the development of PTDM following a liver transplant.MethodsTwo reviewers independently searched three electronic databases Cochrane Central, Scopus, and PubMed until May 2022 for case-control studies that investigated risk factors of PTDM diagnosed in adult liver transplant recipients. The methodological quality of the included studies was assessed with Newcastle-Ottawa Scale (NOS) tool. Meta-analysis was performed using random-effects models to calculate odds ratios (OR) for dichotomous outcomes and weighted mean differences (WMD) for continuous data. A p-value
ISSN:0017-5749
1468-3288
DOI:10.1136/gutjnl-2022-BASL.117