Antibacterial activity of the micro and nanostructures of the optical material tris(8-hydroxyquinoline)aluminum and its application as an antimicrobial coating
Although tris(8-hydroxyquinoline)aluminum (Alq 3 ), a fluorescent optical organometallic material, is known for its applications in optoelectronics, it has only few and limited applications in the biological field. In this study, the antibacterial activity of Alq 3 micro and nanostructures was inves...
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| Veröffentlicht in: | RSC advances 2022-09, Vol.12 (42), p.27131-27144 |
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| creator | Saeed, Abdu Madkhli, Aysh Y Pashameah, Rami Adel Bataweel, Noor M Razvi, Mir Ali Salah, Numan |
| description | Although tris(8-hydroxyquinoline)aluminum (Alq
3
), a fluorescent optical organometallic material, is known for its applications in optoelectronics, it has only few and limited applications in the biological field. In this study, the antibacterial activity of Alq
3
micro and nanostructures was investigated. We prepared Alq
3
nanostructures. We prepared nanosized Alq
3
as rice-like structures that assembled into flower shapes with an α-crystal phase. Then, Alq
3
micro and nanostructure antibacterial activities were estimated against seven human pathogenic bacterial strains. Besides, we compared their antibacterial activities with those of standard antibiotics. The minimal inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and IC50 were evaluated. Alq
3
micro and nanostructure antibacterial activity showed considerable values compared to standard antibiotics. Besides, the obtained data revealed that the antibacterial activity of Alq
3
in nanostructures with a new morphology is more than that in microstructures. The antibacterial activity of Alq
3
nanostructures was attributed to their more surface interactions with the bacterial cell wall. The molecules of 8-hydroxyquinoline in the Alq
3
structure could play crucial roles in its antibacterial activity. To apply the achieved results, Alq
3
was incorporated with polystyrene (PS) in a ratio of 2% to fabricate a PS/Alq
3
composite and used to coat glass beakers, which showed inhibition in the bacterial growth reduced to 65% compared with non-coated beakers. The finding of this study showed that Alq
3
could be used as a promising antimicrobial coating.
This research gives insight into the optical material tris(8-hydroxyquinoline)aluminum (Alq
3
) micro and nanostructures as an antimicrobial agent against different human pathogenic bacteria. In this work, Alq
3
was applied as an antimicrobial coating. |
| doi_str_mv | 10.1039/d2ra04750k |
| format | Article |
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3
), a fluorescent optical organometallic material, is known for its applications in optoelectronics, it has only few and limited applications in the biological field. In this study, the antibacterial activity of Alq
3
micro and nanostructures was investigated. We prepared Alq
3
nanostructures. We prepared nanosized Alq
3
as rice-like structures that assembled into flower shapes with an α-crystal phase. Then, Alq
3
micro and nanostructure antibacterial activities were estimated against seven human pathogenic bacterial strains. Besides, we compared their antibacterial activities with those of standard antibiotics. The minimal inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and IC50 were evaluated. Alq
3
micro and nanostructure antibacterial activity showed considerable values compared to standard antibiotics. Besides, the obtained data revealed that the antibacterial activity of Alq
3
in nanostructures with a new morphology is more than that in microstructures. The antibacterial activity of Alq
3
nanostructures was attributed to their more surface interactions with the bacterial cell wall. The molecules of 8-hydroxyquinoline in the Alq
3
structure could play crucial roles in its antibacterial activity. To apply the achieved results, Alq
3
was incorporated with polystyrene (PS) in a ratio of 2% to fabricate a PS/Alq
3
composite and used to coat glass beakers, which showed inhibition in the bacterial growth reduced to 65% compared with non-coated beakers. The finding of this study showed that Alq
3
could be used as a promising antimicrobial coating.
This research gives insight into the optical material tris(8-hydroxyquinoline)aluminum (Alq
3
) micro and nanostructures as an antimicrobial agent against different human pathogenic bacteria. In this work, Alq
3
was applied as an antimicrobial coating.</description><identifier>ISSN: 2046-2069</identifier><identifier>EISSN: 2046-2069</identifier><identifier>DOI: 10.1039/d2ra04750k</identifier><identifier>PMID: 36276042</identifier><language>eng</language><publisher>England: Royal Society of Chemistry</publisher><subject>Aluminum ; Antibiotics ; Bacteria ; Crystal structure ; Fluorescence ; Hydroxyquinoline ; Molecular structure ; Nanostructure ; Optical materials ; Optoelectronics ; Polystyrene resins</subject><ispartof>RSC advances, 2022-09, Vol.12 (42), p.27131-27144</ispartof><rights>This journal is © The Royal Society of Chemistry.</rights><rights>Copyright Royal Society of Chemistry 2022</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c303t-bc7009875a44d19a00d4e8e261831362e7302d2d903bf20584dc920e6a0811083</citedby><cites>FETCH-LOGICAL-c303t-bc7009875a44d19a00d4e8e261831362e7302d2d903bf20584dc920e6a0811083</cites><orcidid>0000-0002-8233-7373 ; 0000-0002-8506-7188</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,864,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36276042$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Saeed, Abdu</creatorcontrib><creatorcontrib>Madkhli, Aysh Y</creatorcontrib><creatorcontrib>Pashameah, Rami Adel</creatorcontrib><creatorcontrib>Bataweel, Noor M</creatorcontrib><creatorcontrib>Razvi, Mir Ali</creatorcontrib><creatorcontrib>Salah, Numan</creatorcontrib><title>Antibacterial activity of the micro and nanostructures of the optical material tris(8-hydroxyquinoline)aluminum and its application as an antimicrobial coating</title><title>RSC advances</title><addtitle>RSC Adv</addtitle><description>Although tris(8-hydroxyquinoline)aluminum (Alq
3
), a fluorescent optical organometallic material, is known for its applications in optoelectronics, it has only few and limited applications in the biological field. In this study, the antibacterial activity of Alq
3
micro and nanostructures was investigated. We prepared Alq
3
nanostructures. We prepared nanosized Alq
3
as rice-like structures that assembled into flower shapes with an α-crystal phase. Then, Alq
3
micro and nanostructure antibacterial activities were estimated against seven human pathogenic bacterial strains. Besides, we compared their antibacterial activities with those of standard antibiotics. The minimal inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and IC50 were evaluated. Alq
3
micro and nanostructure antibacterial activity showed considerable values compared to standard antibiotics. Besides, the obtained data revealed that the antibacterial activity of Alq
3
in nanostructures with a new morphology is more than that in microstructures. The antibacterial activity of Alq
3
nanostructures was attributed to their more surface interactions with the bacterial cell wall. The molecules of 8-hydroxyquinoline in the Alq
3
structure could play crucial roles in its antibacterial activity. To apply the achieved results, Alq
3
was incorporated with polystyrene (PS) in a ratio of 2% to fabricate a PS/Alq
3
composite and used to coat glass beakers, which showed inhibition in the bacterial growth reduced to 65% compared with non-coated beakers. The finding of this study showed that Alq
3
could be used as a promising antimicrobial coating.
This research gives insight into the optical material tris(8-hydroxyquinoline)aluminum (Alq
3
) micro and nanostructures as an antimicrobial agent against different human pathogenic bacteria. In this work, Alq
3
was applied as an antimicrobial coating.</description><subject>Aluminum</subject><subject>Antibiotics</subject><subject>Bacteria</subject><subject>Crystal structure</subject><subject>Fluorescence</subject><subject>Hydroxyquinoline</subject><subject>Molecular structure</subject><subject>Nanostructure</subject><subject>Optical materials</subject><subject>Optoelectronics</subject><subject>Polystyrene resins</subject><issn>2046-2069</issn><issn>2046-2069</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNpdkU1P3DAQhi1UBGjh0jsoUi_bSqFjO3GS44rSgkCqVLXnyLG9rJfEDv5A3V_DX8X7wYfwwR5rnnlnRi9CnzGcY6DNd0kch6Iq4X4PHREoWE6ANZ_exYfoxPslpMNKTBg-QIeUkYpBQY7Q08wE3XERlNO8z1KgH3VYZXaehYXKBi2czbiRmeHG-uCiCNEp_5K3Y9Ai1Q18JxCc9tM6X6yks_9XD1Eb22ujvvI-DtrEYaOlg8_4OPapNGhrMp6-6U6TbPp1ayFhU87cHaP9Oe-9Otm9E_Tv5-Xfi6v89vev64vZbS4o0JB3ogJo6qrkRSFxwwFkoWqVtq0pTtuqigKRRDZAuzmBsi6kaAgoxqHGGGo6QdOt7ujsQ1Q-tIP2QvU9N8pG35KK1LgoCaMJ_fIBXdroTJpuTeESMyhxor5tqbSQ907N29HpgbtVi6FdO9f-IH9mG-duEny2k4zdoOQr-uJTAk63gPPiNftmPX0GK_ie4g</recordid><startdate>20220922</startdate><enddate>20220922</enddate><creator>Saeed, Abdu</creator><creator>Madkhli, Aysh Y</creator><creator>Pashameah, Rami Adel</creator><creator>Bataweel, Noor M</creator><creator>Razvi, Mir Ali</creator><creator>Salah, Numan</creator><general>Royal Society of Chemistry</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SR</scope><scope>8BQ</scope><scope>8FD</scope><scope>JG9</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-8233-7373</orcidid><orcidid>https://orcid.org/0000-0002-8506-7188</orcidid></search><sort><creationdate>20220922</creationdate><title>Antibacterial activity of the micro and nanostructures of the optical material tris(8-hydroxyquinoline)aluminum and its application as an antimicrobial coating</title><author>Saeed, Abdu ; Madkhli, Aysh Y ; Pashameah, Rami Adel ; Bataweel, Noor M ; Razvi, Mir Ali ; Salah, Numan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c303t-bc7009875a44d19a00d4e8e261831362e7302d2d903bf20584dc920e6a0811083</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Aluminum</topic><topic>Antibiotics</topic><topic>Bacteria</topic><topic>Crystal structure</topic><topic>Fluorescence</topic><topic>Hydroxyquinoline</topic><topic>Molecular structure</topic><topic>Nanostructure</topic><topic>Optical materials</topic><topic>Optoelectronics</topic><topic>Polystyrene resins</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Saeed, Abdu</creatorcontrib><creatorcontrib>Madkhli, Aysh Y</creatorcontrib><creatorcontrib>Pashameah, Rami Adel</creatorcontrib><creatorcontrib>Bataweel, Noor M</creatorcontrib><creatorcontrib>Razvi, Mir Ali</creatorcontrib><creatorcontrib>Salah, Numan</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Engineered Materials Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><collection>MEDLINE - Academic</collection><jtitle>RSC advances</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Saeed, Abdu</au><au>Madkhli, Aysh Y</au><au>Pashameah, Rami Adel</au><au>Bataweel, Noor M</au><au>Razvi, Mir Ali</au><au>Salah, Numan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Antibacterial activity of the micro and nanostructures of the optical material tris(8-hydroxyquinoline)aluminum and its application as an antimicrobial coating</atitle><jtitle>RSC advances</jtitle><addtitle>RSC Adv</addtitle><date>2022-09-22</date><risdate>2022</risdate><volume>12</volume><issue>42</issue><spage>27131</spage><epage>27144</epage><pages>27131-27144</pages><issn>2046-2069</issn><eissn>2046-2069</eissn><abstract>Although tris(8-hydroxyquinoline)aluminum (Alq
3
), a fluorescent optical organometallic material, is known for its applications in optoelectronics, it has only few and limited applications in the biological field. In this study, the antibacterial activity of Alq
3
micro and nanostructures was investigated. We prepared Alq
3
nanostructures. We prepared nanosized Alq
3
as rice-like structures that assembled into flower shapes with an α-crystal phase. Then, Alq
3
micro and nanostructure antibacterial activities were estimated against seven human pathogenic bacterial strains. Besides, we compared their antibacterial activities with those of standard antibiotics. The minimal inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and IC50 were evaluated. Alq
3
micro and nanostructure antibacterial activity showed considerable values compared to standard antibiotics. Besides, the obtained data revealed that the antibacterial activity of Alq
3
in nanostructures with a new morphology is more than that in microstructures. The antibacterial activity of Alq
3
nanostructures was attributed to their more surface interactions with the bacterial cell wall. The molecules of 8-hydroxyquinoline in the Alq
3
structure could play crucial roles in its antibacterial activity. To apply the achieved results, Alq
3
was incorporated with polystyrene (PS) in a ratio of 2% to fabricate a PS/Alq
3
composite and used to coat glass beakers, which showed inhibition in the bacterial growth reduced to 65% compared with non-coated beakers. The finding of this study showed that Alq
3
could be used as a promising antimicrobial coating.
This research gives insight into the optical material tris(8-hydroxyquinoline)aluminum (Alq
3
) micro and nanostructures as an antimicrobial agent against different human pathogenic bacteria. In this work, Alq
3
was applied as an antimicrobial coating.</abstract><cop>England</cop><pub>Royal Society of Chemistry</pub><pmid>36276042</pmid><doi>10.1039/d2ra04750k</doi><tpages>14</tpages><orcidid>https://orcid.org/0000-0002-8233-7373</orcidid><orcidid>https://orcid.org/0000-0002-8506-7188</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2046-2069 |
| ispartof | RSC advances, 2022-09, Vol.12 (42), p.27131-27144 |
| issn | 2046-2069 2046-2069 |
| language | eng |
| recordid | cdi_proquest_journals_2721516051 |
| source | DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central Open Access; PubMed Central |
| subjects | Aluminum Antibiotics Bacteria Crystal structure Fluorescence Hydroxyquinoline Molecular structure Nanostructure Optical materials Optoelectronics Polystyrene resins |
| title | Antibacterial activity of the micro and nanostructures of the optical material tris(8-hydroxyquinoline)aluminum and its application as an antimicrobial coating |
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