Synthesis and characterization of impurities of Apixaban drug substance—An anticoagulant

Apixaban is an anticoagulant used to treat venous thromboembolic disorders. The present work describes the origin and synthesis of related substances of Apixaban PG ester‐1 and PG ester‐2. These impurities arise in the process of Apixaban drug substance, later these impurities are transformed into t...

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Veröffentlicht in:	Journal of heterocyclic chemistry 2022-10, Vol.59 (10), p.1736-1741
Hauptverfasser:	Satheesh, Deekonda, Sreenivasulu, B., Reddy, Bhavanam Sekhara, Reddy, U. Rajasekhar, Saladi, J. S. Chakradhar, Gupta, P. Badrinath, Reddy, Aaramadaka Sunil Kumar, Aegurla, Balakrishna, Basavaiah, Keloth
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticoagulants Impurities NMR Nuclear magnetic resonance Synthesis
Online-Zugang:	Volltext
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