Induction of angiogenesis and neural progenitor cells by basic fibroblast growth factor‐releasing polyglycolic acid sheet following focal cerebral infarction in mice

Biodegradable sheets loaded with basic fibroblast growth factor (bFGF) are prepared as novel bFGF‐releasing systems from polyglycolic acid nonwoven fabric by oxygen plasma treatment followed by bFGF adsorption. In the present study, we investigated the therapeutic effects of this system on a focal c...

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Veröffentlicht in:	Journal of biomedical materials research. Part A 2022-12, Vol.110 (12), p.1964-1975
Hauptverfasser:	Ito, Yoshiro, Oyane, Ayako, Yasunaga, Mayu, Hirata, Koji, Hirose, Motohiro, Tsurushima, Hideo, Ito, Yuzuru, Matsumaru, Yuji, Ishikawa, Eiichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis basic fibroblast growth factor (bFGF) Biodegradability Biodegradation Biological activity Cell culture Cells (biology) Cerebral infarction Fibroblast growth factor 2 Fibroblasts Growth factors Infarction Neostriatum neural progenitor cell Neural stem cells Nonwoven fabrics Oxygen plasma oxygen plasma treatment Polyglycolic acid Polylactic acid Progenitor cells Releasing releasing system Subventricular zone Vascular endothelial growth factor
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