Insulin receptor tyrosine kinase substrate (IRTKS) promotes the tumorigenesis of pancreatic cancer via PI3K/AKT signaling

Pancreatic cancer (PC) is a common type of tumor, which ranks for the seventh leading cause of cancer death worldwide. Insulin receptor tyrosine kinase substrate (IRTKS) plays an important regulatory role in cell proliferation, motility and survival. In this study, we explore the effect of IRTKS on...

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Veröffentlicht in:	Human cell : official journal of Human Cell Research Society 2022-11, Vol.35 (6), p.1885-1899
Hauptverfasser:	Lu, Yu, Zhou, Xin-Yuan, Zhou, Cheng-Liang, Liu, Jie, Yong, Tao, Fan, Yong, Wang, Chen
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 3-kinase AKT protein Biomedical and Life Sciences Carcinogenesis - genetics Cell Biology Cell Line, Tumor Cell Movement - genetics Cell proliferation Cell Proliferation - genetics Cell survival Cholecystokinin Gynecology Humans Insulin Life Sciences Medical prognosis Microfilament Proteins Oncology Pancreatic cancer Pancreatic Neoplasms Pancreatic Neoplasms - pathology Phosphatidylinositol 3-Kinases - genetics Phosphatidylinositol 3-Kinases - metabolism Protein-tyrosine kinase receptors Protein-Tyrosine Kinases Proto-Oncogene Proteins c-akt - metabolism Reproductive Medicine Research Article Signal transduction Stem Cells Surgery Tumorigenesis
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