Copper(II) Complexes with 5-Nitro-2-furoic Acid: Synthesis, Structure, Thermal Properties, and Biological Activity
Reaction of copper(II) acetate with 5-nitro-2-furoic acid (NO 2 -Hfur) and N-donor ligands 2,2'‑bipyridine (bpy) and pyridine (py) has resulted in complexes [Cu(NO 2 -fur) 2 (H 2 O) 2 ]·2H 2 O ( I ), [Cu(NO 2 -fur) 2 (py) 2 (H 2 O)] ( II ), and binuclear [Cu 2 (NO 2 -fur) 4 (bpy) 2 ]·H 2 O ( II...
Gespeichert in:
| Veröffentlicht in: | Russian journal of inorganic chemistry 2022-10, Vol.67 (10), p.1545-1556 |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1556 |
|---|---|
| container_issue | 10 |
| container_start_page | 1545 |
| container_title | Russian journal of inorganic chemistry |
| container_volume | 67 |
| creator | Koshenskova, K. A. Lutsenko, I. A. Nelyubina, Yu. V. Primakov, P. V. Aliev, T. M. Bekker, O. B. Khoroshilov, A. V. Mantrov, S. N. Kiskin, M. A. Eremenko, I. L. |
| description | Reaction of copper(II) acetate with 5-nitro-2-furoic acid (NO
2
-Hfur) and N-donor ligands 2,2'‑bipyridine (bpy) and pyridine (py) has resulted in complexes [Cu(NO
2
-fur)
2
(H
2
O)
2
]·2H
2
O (
I
), [Cu(NO
2
-fur)
2
(py)
2
(H
2
O)] (
II
), and binuclear [Cu
2
(NO
2
-fur)
4
(bpy)
2
]·H
2
O (
III
) whose structure was determined by X‑ray diffraction study. Cation Cu
2+
is in square-planar (
I
) or square-pyramidal (
II
,
III
) environment and has CN(Cu) = 4 (
I
) or 5 (
II
,
III
), respectively. Stability of complexes
I
–
III
in solid phase has been determined by synchronous thermal analysis, stability in solutions has been studied by electronic absorption spectroscopy. Compounds
I
and
II
are thermally stable (>100°С). The presence of nitro group in the complexes causes strong exothermal effects, whose intensity is leveled by donor ligand. The storage of solutions of the compounds in 5% glucose solution and 0.9% NaCl for 2 days according to UV spectroscopy causes no their degradation. Biological activity of complexes
I
–
III
was studied in vitro toward non-pathogenic strain
M. smegmatis
(behaves as a model for
M. tuberculosis
); antimicrobial activity of compound
II
toward a number of Gram-positive and Gram-negative bacteria has been investigated. |
| doi_str_mv | 10.1134/S003602362270005X |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_2718668781</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2718668781</sourcerecordid><originalsourceid>FETCH-LOGICAL-c316t-eb0eac598e93f041b0ac682c4d4883ea4ac29e67c14813f8a5d2af3833cbb4f53</originalsourceid><addsrcrecordid>eNp1kF1LwzAYhYMoOKc_wLuANwqL5qtp5t0sfgxEhU3wrqRpumV0TU1Sdf_ejgleiFfvxXOe88IB4JTgS0IYv5phzASmTFCaYoyTtz0wIAkjSArC9sFgi9GWH4KjEFYYc45TOQA-c21r_Pl0egEzt25r82UC_LRxCRP0ZKN3iKKq885qONG2vIazTROXJtgwgrPoOx07b0ZwvjR-rWr44l1fF63psWpKeGNd7RZW92iio_2wcXMMDipVB3Pyc4fg9e52nj2gx-f7aTZ5RJoREZEpsFE6GUszZhXmpMBKC0k1L7mUzCiuNB0bkWrCJWGVVElJVcUkY7ooeJWwITjb9bbevXcmxHzlOt_0L3OaEimETHtxCMgupb0LwZsqb71dK7_JCc630-Z_pu0dunNCn20Wxv82_y99A5vAeso</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2718668781</pqid></control><display><type>article</type><title>Copper(II) Complexes with 5-Nitro-2-furoic Acid: Synthesis, Structure, Thermal Properties, and Biological Activity</title><source>SpringerNature Journals</source><creator>Koshenskova, K. A. ; Lutsenko, I. A. ; Nelyubina, Yu. V. ; Primakov, P. V. ; Aliev, T. M. ; Bekker, O. B. ; Khoroshilov, A. V. ; Mantrov, S. N. ; Kiskin, M. A. ; Eremenko, I. L.</creator><creatorcontrib>Koshenskova, K. A. ; Lutsenko, I. A. ; Nelyubina, Yu. V. ; Primakov, P. V. ; Aliev, T. M. ; Bekker, O. B. ; Khoroshilov, A. V. ; Mantrov, S. N. ; Kiskin, M. A. ; Eremenko, I. L.</creatorcontrib><description>Reaction of copper(II) acetate with 5-nitro-2-furoic acid (NO
2
-Hfur) and N-donor ligands 2,2'‑bipyridine (bpy) and pyridine (py) has resulted in complexes [Cu(NO
2
-fur)
2
(H
2
O)
2
]·2H
2
O (
I
), [Cu(NO
2
-fur)
2
(py)
2
(H
2
O)] (
II
), and binuclear [Cu
2
(NO
2
-fur)
4
(bpy)
2
]·H
2
O (
III
) whose structure was determined by X‑ray diffraction study. Cation Cu
2+
is in square-planar (
I
) or square-pyramidal (
II
,
III
) environment and has CN(Cu) = 4 (
I
) or 5 (
II
,
III
), respectively. Stability of complexes
I
–
III
in solid phase has been determined by synchronous thermal analysis, stability in solutions has been studied by electronic absorption spectroscopy. Compounds
I
and
II
are thermally stable (>100°С). The presence of nitro group in the complexes causes strong exothermal effects, whose intensity is leveled by donor ligand. The storage of solutions of the compounds in 5% glucose solution and 0.9% NaCl for 2 days according to UV spectroscopy causes no their degradation. Biological activity of complexes
I
–
III
was studied in vitro toward non-pathogenic strain
M. smegmatis
(behaves as a model for
M. tuberculosis
); antimicrobial activity of compound
II
toward a number of Gram-positive and Gram-negative bacteria has been investigated.</description><identifier>ISSN: 0036-0236</identifier><identifier>EISSN: 1531-8613</identifier><identifier>DOI: 10.1134/S003602362270005X</identifier><language>eng</language><publisher>Moscow: Pleiades Publishing</publisher><subject>Antiinfectives and antibacterials ; Biological activity ; Biological properties ; Chemistry ; Chemistry and Materials Science ; Coordination Compounds ; Copper ; Furoic acid ; Inorganic Chemistry ; Ligands ; Nitrogen dioxide ; Solid phases ; Spectrum analysis ; Stability analysis ; Thermal analysis ; Thermal stability ; Thermodynamic properties</subject><ispartof>Russian journal of inorganic chemistry, 2022-10, Vol.67 (10), p.1545-1556</ispartof><rights>Pleiades Publishing, Ltd. 2022. ISSN 0036-0236, Russian Journal of Inorganic Chemistry, 2022, Vol. 67, No. 10, pp. 1545–1556. © Pleiades Publishing, Ltd., 2022. Russian Text © The Author(s), 2022, published in Zhurnal Neorganicheskoi Khimii, 2022, Vol. 67, No. 10, pp. 1398–1410.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c316t-eb0eac598e93f041b0ac682c4d4883ea4ac29e67c14813f8a5d2af3833cbb4f53</citedby><cites>FETCH-LOGICAL-c316t-eb0eac598e93f041b0ac682c4d4883ea4ac29e67c14813f8a5d2af3833cbb4f53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1134/S003602362270005X$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1134/S003602362270005X$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids></links><search><creatorcontrib>Koshenskova, K. A.</creatorcontrib><creatorcontrib>Lutsenko, I. A.</creatorcontrib><creatorcontrib>Nelyubina, Yu. V.</creatorcontrib><creatorcontrib>Primakov, P. V.</creatorcontrib><creatorcontrib>Aliev, T. M.</creatorcontrib><creatorcontrib>Bekker, O. B.</creatorcontrib><creatorcontrib>Khoroshilov, A. V.</creatorcontrib><creatorcontrib>Mantrov, S. N.</creatorcontrib><creatorcontrib>Kiskin, M. A.</creatorcontrib><creatorcontrib>Eremenko, I. L.</creatorcontrib><title>Copper(II) Complexes with 5-Nitro-2-furoic Acid: Synthesis, Structure, Thermal Properties, and Biological Activity</title><title>Russian journal of inorganic chemistry</title><addtitle>Russ. J. Inorg. Chem</addtitle><description>Reaction of copper(II) acetate with 5-nitro-2-furoic acid (NO
2
-Hfur) and N-donor ligands 2,2'‑bipyridine (bpy) and pyridine (py) has resulted in complexes [Cu(NO
2
-fur)
2
(H
2
O)
2
]·2H
2
O (
I
), [Cu(NO
2
-fur)
2
(py)
2
(H
2
O)] (
II
), and binuclear [Cu
2
(NO
2
-fur)
4
(bpy)
2
]·H
2
O (
III
) whose structure was determined by X‑ray diffraction study. Cation Cu
2+
is in square-planar (
I
) or square-pyramidal (
II
,
III
) environment and has CN(Cu) = 4 (
I
) or 5 (
II
,
III
), respectively. Stability of complexes
I
–
III
in solid phase has been determined by synchronous thermal analysis, stability in solutions has been studied by electronic absorption spectroscopy. Compounds
I
and
II
are thermally stable (>100°С). The presence of nitro group in the complexes causes strong exothermal effects, whose intensity is leveled by donor ligand. The storage of solutions of the compounds in 5% glucose solution and 0.9% NaCl for 2 days according to UV spectroscopy causes no their degradation. Biological activity of complexes
I
–
III
was studied in vitro toward non-pathogenic strain
M. smegmatis
(behaves as a model for
M. tuberculosis
); antimicrobial activity of compound
II
toward a number of Gram-positive and Gram-negative bacteria has been investigated.</description><subject>Antiinfectives and antibacterials</subject><subject>Biological activity</subject><subject>Biological properties</subject><subject>Chemistry</subject><subject>Chemistry and Materials Science</subject><subject>Coordination Compounds</subject><subject>Copper</subject><subject>Furoic acid</subject><subject>Inorganic Chemistry</subject><subject>Ligands</subject><subject>Nitrogen dioxide</subject><subject>Solid phases</subject><subject>Spectrum analysis</subject><subject>Stability analysis</subject><subject>Thermal analysis</subject><subject>Thermal stability</subject><subject>Thermodynamic properties</subject><issn>0036-0236</issn><issn>1531-8613</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNp1kF1LwzAYhYMoOKc_wLuANwqL5qtp5t0sfgxEhU3wrqRpumV0TU1Sdf_ejgleiFfvxXOe88IB4JTgS0IYv5phzASmTFCaYoyTtz0wIAkjSArC9sFgi9GWH4KjEFYYc45TOQA-c21r_Pl0egEzt25r82UC_LRxCRP0ZKN3iKKq885qONG2vIazTROXJtgwgrPoOx07b0ZwvjR-rWr44l1fF63psWpKeGNd7RZW92iio_2wcXMMDipVB3Pyc4fg9e52nj2gx-f7aTZ5RJoREZEpsFE6GUszZhXmpMBKC0k1L7mUzCiuNB0bkWrCJWGVVElJVcUkY7ooeJWwITjb9bbevXcmxHzlOt_0L3OaEimETHtxCMgupb0LwZsqb71dK7_JCc630-Z_pu0dunNCn20Wxv82_y99A5vAeso</recordid><startdate>20221001</startdate><enddate>20221001</enddate><creator>Koshenskova, K. A.</creator><creator>Lutsenko, I. A.</creator><creator>Nelyubina, Yu. V.</creator><creator>Primakov, P. V.</creator><creator>Aliev, T. M.</creator><creator>Bekker, O. B.</creator><creator>Khoroshilov, A. V.</creator><creator>Mantrov, S. N.</creator><creator>Kiskin, M. A.</creator><creator>Eremenko, I. L.</creator><general>Pleiades Publishing</general><general>Springer Nature B.V</general><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20221001</creationdate><title>Copper(II) Complexes with 5-Nitro-2-furoic Acid: Synthesis, Structure, Thermal Properties, and Biological Activity</title><author>Koshenskova, K. A. ; Lutsenko, I. A. ; Nelyubina, Yu. V. ; Primakov, P. V. ; Aliev, T. M. ; Bekker, O. B. ; Khoroshilov, A. V. ; Mantrov, S. N. ; Kiskin, M. A. ; Eremenko, I. L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c316t-eb0eac598e93f041b0ac682c4d4883ea4ac29e67c14813f8a5d2af3833cbb4f53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Antiinfectives and antibacterials</topic><topic>Biological activity</topic><topic>Biological properties</topic><topic>Chemistry</topic><topic>Chemistry and Materials Science</topic><topic>Coordination Compounds</topic><topic>Copper</topic><topic>Furoic acid</topic><topic>Inorganic Chemistry</topic><topic>Ligands</topic><topic>Nitrogen dioxide</topic><topic>Solid phases</topic><topic>Spectrum analysis</topic><topic>Stability analysis</topic><topic>Thermal analysis</topic><topic>Thermal stability</topic><topic>Thermodynamic properties</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Koshenskova, K. A.</creatorcontrib><creatorcontrib>Lutsenko, I. A.</creatorcontrib><creatorcontrib>Nelyubina, Yu. V.</creatorcontrib><creatorcontrib>Primakov, P. V.</creatorcontrib><creatorcontrib>Aliev, T. M.</creatorcontrib><creatorcontrib>Bekker, O. B.</creatorcontrib><creatorcontrib>Khoroshilov, A. V.</creatorcontrib><creatorcontrib>Mantrov, S. N.</creatorcontrib><creatorcontrib>Kiskin, M. A.</creatorcontrib><creatorcontrib>Eremenko, I. L.</creatorcontrib><collection>CrossRef</collection><jtitle>Russian journal of inorganic chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Koshenskova, K. A.</au><au>Lutsenko, I. A.</au><au>Nelyubina, Yu. V.</au><au>Primakov, P. V.</au><au>Aliev, T. M.</au><au>Bekker, O. B.</au><au>Khoroshilov, A. V.</au><au>Mantrov, S. N.</au><au>Kiskin, M. A.</au><au>Eremenko, I. L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Copper(II) Complexes with 5-Nitro-2-furoic Acid: Synthesis, Structure, Thermal Properties, and Biological Activity</atitle><jtitle>Russian journal of inorganic chemistry</jtitle><stitle>Russ. J. Inorg. Chem</stitle><date>2022-10-01</date><risdate>2022</risdate><volume>67</volume><issue>10</issue><spage>1545</spage><epage>1556</epage><pages>1545-1556</pages><issn>0036-0236</issn><eissn>1531-8613</eissn><abstract>Reaction of copper(II) acetate with 5-nitro-2-furoic acid (NO
2
-Hfur) and N-donor ligands 2,2'‑bipyridine (bpy) and pyridine (py) has resulted in complexes [Cu(NO
2
-fur)
2
(H
2
O)
2
]·2H
2
O (
I
), [Cu(NO
2
-fur)
2
(py)
2
(H
2
O)] (
II
), and binuclear [Cu
2
(NO
2
-fur)
4
(bpy)
2
]·H
2
O (
III
) whose structure was determined by X‑ray diffraction study. Cation Cu
2+
is in square-planar (
I
) or square-pyramidal (
II
,
III
) environment and has CN(Cu) = 4 (
I
) or 5 (
II
,
III
), respectively. Stability of complexes
I
–
III
in solid phase has been determined by synchronous thermal analysis, stability in solutions has been studied by electronic absorption spectroscopy. Compounds
I
and
II
are thermally stable (>100°С). The presence of nitro group in the complexes causes strong exothermal effects, whose intensity is leveled by donor ligand. The storage of solutions of the compounds in 5% glucose solution and 0.9% NaCl for 2 days according to UV spectroscopy causes no their degradation. Biological activity of complexes
I
–
III
was studied in vitro toward non-pathogenic strain
M. smegmatis
(behaves as a model for
M. tuberculosis
); antimicrobial activity of compound
II
toward a number of Gram-positive and Gram-negative bacteria has been investigated.</abstract><cop>Moscow</cop><pub>Pleiades Publishing</pub><doi>10.1134/S003602362270005X</doi><tpages>12</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0036-0236 |
| ispartof | Russian journal of inorganic chemistry, 2022-10, Vol.67 (10), p.1545-1556 |
| issn | 0036-0236 1531-8613 |
| language | eng |
| recordid | cdi_proquest_journals_2718668781 |
| source | SpringerNature Journals |
| subjects | Antiinfectives and antibacterials Biological activity Biological properties Chemistry Chemistry and Materials Science Coordination Compounds Copper Furoic acid Inorganic Chemistry Ligands Nitrogen dioxide Solid phases Spectrum analysis Stability analysis Thermal analysis Thermal stability Thermodynamic properties |
| title | Copper(II) Complexes with 5-Nitro-2-furoic Acid: Synthesis, Structure, Thermal Properties, and Biological Activity |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T13%3A39%3A22IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Copper(II)%20Complexes%20with%205-Nitro-2-furoic%20Acid:%20Synthesis,%20Structure,%20Thermal%20Properties,%20and%20Biological%20Activity&rft.jtitle=Russian%20journal%20of%20inorganic%20chemistry&rft.au=Koshenskova,%20K.%20A.&rft.date=2022-10-01&rft.volume=67&rft.issue=10&rft.spage=1545&rft.epage=1556&rft.pages=1545-1556&rft.issn=0036-0236&rft.eissn=1531-8613&rft_id=info:doi/10.1134/S003602362270005X&rft_dat=%3Cproquest_cross%3E2718668781%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2718668781&rft_id=info:pmid/&rfr_iscdi=true |