Synthesis and evaluation of aryl aminomethylene substituted barbiturates and thiobarbiturates as novel α-amylase inhibitors and radical scavengers

A widespread increase in people affected by diabetes mellitus (DM) has led to the development of new strategies to combat this disease. Targeting the activity of the α -amylase enzyme and preventing oxidative stress involved in the onset and progression of type 2 DM is considered to represent the mo...

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