Disseminated small cortical lesions of stroke‐like episodes in a patient with MELAS with an m.3271T>C mutation
Little is known about magnetic resonance imaging findings in patients with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke‐like episodes (MELAS) with the m.3271 A > G mutation. A 31‐year‐old man presented with headache and left‐sided homonymous hemianopsia. Brain magnetic reso...
Gespeichert in:
| Veröffentlicht in: | Neurology and clinical neuroscience 2022-09, Vol.10 (5), p.259-261 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 261 |
|---|---|
| container_issue | 5 |
| container_start_page | 259 |
| container_title | Neurology and clinical neuroscience |
| container_volume | 10 |
| creator | Ken‐ichi Shibata Mukai, Tatsuya Nakagaki, Hideaki Nagano, Sukehisa |
| description | Little is known about magnetic resonance imaging findings in patients with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke‐like episodes (MELAS) with the m.3271 A > G mutation. A 31‐year‐old man presented with headache and left‐sided homonymous hemianopsia. Brain magnetic resonance imaging showed hyperintensities in the right occipital lobe on diffusion‐ and T2‐weighted imaging. MELAS was diagnosed, and the etiological mutation was identified as m.3271 T > C. Although his symptoms gradually resolved, magnetic resonance imaging revealed disseminated small cortical lesions in the left occipital lobe. We report a rare case of atypical stroke‐like lesions in a patient with MELAS with the m.3271 T > C mutation. |
| doi_str_mv | 10.1111/ncn3.12655 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest</sourceid><recordid>TN_cdi_proquest_journals_2709807848</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2709807848</sourcerecordid><originalsourceid>FETCH-LOGICAL-j528-b438c0f7a533b4cf180b57e61b35c23635125ab4098e42b5acab63a9e482b73f3</originalsourceid><addsrcrecordid>eNotjbtOwzAYhS0kJKrShSewxJxg-7djZ0GqSrlIQQx0r2zXEU4TO8SuWHkEnpEnIVL5lnOGc0HohpKSztwFG6CkrBLiAi0Y4XXBqYQrtEqpIzN1DbRWCzQ--JTc4IPO7oDToPse2zhlb3WPe5d8DAnHFqc8xaP7_f7p_dFhN_oUDy5hH7DGo87ehYy_fP7Ar9tm_X62OuChBCbp7n6Dh1OeYzFco8tW98mt_nWJdo_b3ea5aN6eXjbrpugEU4XhoCxppRYAhtuWKmKEdBU1ICyDCgRlQhtOauU4M0JbbSrQteOKGQktLNHteXac4ufJpbzv4mkK8-OeyblFpOIK_gAtrVnE</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2709807848</pqid></control><display><type>article</type><title>Disseminated small cortical lesions of stroke‐like episodes in a patient with MELAS with an m.3271T>C mutation</title><source>Wiley Online Library Journals Frontfile Complete</source><creator>Ken‐ichi Shibata ; Mukai, Tatsuya ; Nakagaki, Hideaki ; Nagano, Sukehisa</creator><creatorcontrib>Ken‐ichi Shibata ; Mukai, Tatsuya ; Nakagaki, Hideaki ; Nagano, Sukehisa</creatorcontrib><description>Little is known about magnetic resonance imaging findings in patients with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke‐like episodes (MELAS) with the m.3271 A > G mutation. A 31‐year‐old man presented with headache and left‐sided homonymous hemianopsia. Brain magnetic resonance imaging showed hyperintensities in the right occipital lobe on diffusion‐ and T2‐weighted imaging. MELAS was diagnosed, and the etiological mutation was identified as m.3271 T > C. Although his symptoms gradually resolved, magnetic resonance imaging revealed disseminated small cortical lesions in the left occipital lobe. We report a rare case of atypical stroke‐like lesions in a patient with MELAS with the m.3271 T > C mutation.</description><identifier>EISSN: 2049-4173</identifier><identifier>DOI: 10.1111/ncn3.12655</identifier><language>eng</language><publisher>Tokyo: Wiley Subscription Services, Inc</publisher><subject>Acidosis ; Encephalopathy ; Lactic acidosis ; Lesions ; Magnetic resonance imaging ; MELAS syndrome ; Mitochondria ; Mutation ; Myopathy ; Neuroimaging ; Occipital lobe</subject><ispartof>Neurology and clinical neuroscience, 2022-09, Vol.10 (5), p.259-261</ispartof><rights>2022 Japanese Society of Neurology and John Wiley & Sons Australia, Ltd</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids></links><search><creatorcontrib>Ken‐ichi Shibata</creatorcontrib><creatorcontrib>Mukai, Tatsuya</creatorcontrib><creatorcontrib>Nakagaki, Hideaki</creatorcontrib><creatorcontrib>Nagano, Sukehisa</creatorcontrib><title>Disseminated small cortical lesions of stroke‐like episodes in a patient with MELAS with an m.3271T>C mutation</title><title>Neurology and clinical neuroscience</title><description>Little is known about magnetic resonance imaging findings in patients with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke‐like episodes (MELAS) with the m.3271 A > G mutation. A 31‐year‐old man presented with headache and left‐sided homonymous hemianopsia. Brain magnetic resonance imaging showed hyperintensities in the right occipital lobe on diffusion‐ and T2‐weighted imaging. MELAS was diagnosed, and the etiological mutation was identified as m.3271 T > C. Although his symptoms gradually resolved, magnetic resonance imaging revealed disseminated small cortical lesions in the left occipital lobe. We report a rare case of atypical stroke‐like lesions in a patient with MELAS with the m.3271 T > C mutation.</description><subject>Acidosis</subject><subject>Encephalopathy</subject><subject>Lactic acidosis</subject><subject>Lesions</subject><subject>Magnetic resonance imaging</subject><subject>MELAS syndrome</subject><subject>Mitochondria</subject><subject>Mutation</subject><subject>Myopathy</subject><subject>Neuroimaging</subject><subject>Occipital lobe</subject><issn>2049-4173</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNotjbtOwzAYhS0kJKrShSewxJxg-7djZ0GqSrlIQQx0r2zXEU4TO8SuWHkEnpEnIVL5lnOGc0HohpKSztwFG6CkrBLiAi0Y4XXBqYQrtEqpIzN1DbRWCzQ--JTc4IPO7oDToPse2zhlb3WPe5d8DAnHFqc8xaP7_f7p_dFhN_oUDy5hH7DGo87ehYy_fP7Ar9tm_X62OuChBCbp7n6Dh1OeYzFco8tW98mt_nWJdo_b3ea5aN6eXjbrpugEU4XhoCxppRYAhtuWKmKEdBU1ICyDCgRlQhtOauU4M0JbbSrQteOKGQktLNHteXac4ufJpbzv4mkK8-OeyblFpOIK_gAtrVnE</recordid><startdate>20220901</startdate><enddate>20220901</enddate><creator>Ken‐ichi Shibata</creator><creator>Mukai, Tatsuya</creator><creator>Nakagaki, Hideaki</creator><creator>Nagano, Sukehisa</creator><general>Wiley Subscription Services, Inc</general><scope>7TK</scope><scope>K9.</scope></search><sort><creationdate>20220901</creationdate><title>Disseminated small cortical lesions of stroke‐like episodes in a patient with MELAS with an m.3271T>C mutation</title><author>Ken‐ichi Shibata ; Mukai, Tatsuya ; Nakagaki, Hideaki ; Nagano, Sukehisa</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-j528-b438c0f7a533b4cf180b57e61b35c23635125ab4098e42b5acab63a9e482b73f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Acidosis</topic><topic>Encephalopathy</topic><topic>Lactic acidosis</topic><topic>Lesions</topic><topic>Magnetic resonance imaging</topic><topic>MELAS syndrome</topic><topic>Mitochondria</topic><topic>Mutation</topic><topic>Myopathy</topic><topic>Neuroimaging</topic><topic>Occipital lobe</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ken‐ichi Shibata</creatorcontrib><creatorcontrib>Mukai, Tatsuya</creatorcontrib><creatorcontrib>Nakagaki, Hideaki</creatorcontrib><creatorcontrib>Nagano, Sukehisa</creatorcontrib><collection>Neurosciences Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><jtitle>Neurology and clinical neuroscience</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ken‐ichi Shibata</au><au>Mukai, Tatsuya</au><au>Nakagaki, Hideaki</au><au>Nagano, Sukehisa</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Disseminated small cortical lesions of stroke‐like episodes in a patient with MELAS with an m.3271T>C mutation</atitle><jtitle>Neurology and clinical neuroscience</jtitle><date>2022-09-01</date><risdate>2022</risdate><volume>10</volume><issue>5</issue><spage>259</spage><epage>261</epage><pages>259-261</pages><eissn>2049-4173</eissn><abstract>Little is known about magnetic resonance imaging findings in patients with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke‐like episodes (MELAS) with the m.3271 A > G mutation. A 31‐year‐old man presented with headache and left‐sided homonymous hemianopsia. Brain magnetic resonance imaging showed hyperintensities in the right occipital lobe on diffusion‐ and T2‐weighted imaging. MELAS was diagnosed, and the etiological mutation was identified as m.3271 T > C. Although his symptoms gradually resolved, magnetic resonance imaging revealed disseminated small cortical lesions in the left occipital lobe. We report a rare case of atypical stroke‐like lesions in a patient with MELAS with the m.3271 T > C mutation.</abstract><cop>Tokyo</cop><pub>Wiley Subscription Services, Inc</pub><doi>10.1111/ncn3.12655</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | EISSN: 2049-4173 |
| ispartof | Neurology and clinical neuroscience, 2022-09, Vol.10 (5), p.259-261 |
| issn | 2049-4173 |
| language | eng |
| recordid | cdi_proquest_journals_2709807848 |
| source | Wiley Online Library Journals Frontfile Complete |
| subjects | Acidosis Encephalopathy Lactic acidosis Lesions Magnetic resonance imaging MELAS syndrome Mitochondria Mutation Myopathy Neuroimaging Occipital lobe |
| title | Disseminated small cortical lesions of stroke‐like episodes in a patient with MELAS with an m.3271T>C mutation |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-09T21%3A24%3A20IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Disseminated%20small%20cortical%20lesions%20of%20stroke%E2%80%90like%20episodes%20in%20a%20patient%20with%20MELAS%20with%20an%20m.3271T%3EC%20mutation&rft.jtitle=Neurology%20and%20clinical%20neuroscience&rft.au=Ken%E2%80%90ichi%20Shibata&rft.date=2022-09-01&rft.volume=10&rft.issue=5&rft.spage=259&rft.epage=261&rft.pages=259-261&rft.eissn=2049-4173&rft_id=info:doi/10.1111/ncn3.12655&rft_dat=%3Cproquest%3E2709807848%3C/proquest%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2709807848&rft_id=info:pmid/&rfr_iscdi=true |