The Role of Multilayer Electrospun Poly(Vinyl Alcohol)/Gelatin nanofibers loaded with Fluconazole and Cinnamaldehyde in the Potential Treatment of Fungal Keratitis

[Display omitted] •CA and FLU-loaded PVA/GEL fibers were successfully produced with electrospinning.•CA layer is for to inhibit the biofilm and FLU layer provides antifungal effect.•CA and FLU were released from nanofibers in a controlled release manner. Fungal keratitis is a severe corneal infecti...

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Veröffentlicht in:	European polymer journal 2022-08, Vol.176, p.111390, Article 111390
Hauptverfasser:	Ilhan, Elif, Cesur, Sumeyye, Sulutas, Rabia Betul, Pilavci, Esra, Dalbayrak, Basak, Kaya, Elif, Arisan, Elif Damla, Tinaz, Gulgun Bosgelmez, Sengor, Mustafa, Kijeńska-Gawrońska, Ewa, Oktar, Faik Nuzhet, Gunduz, Oguzhan
Format:	Artikel
Sprache:	eng
Schlagworte:	Antifungal agents Biofilms Cinnamaldehyde Cornea Cornea tissue engineering Drug delivery systems Electrospinning Essential oils Eye diseases Fluconazole Fourier transforms Fungal infections Fungal keratitis Fungi Fungicides Gelatin Infrared analysis Infrared spectroscopy Keratitis Mechanical analysis Multilayers Nanofiber Nanofibers Polyvinyl alcohol
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