A Randomized Thorough QT Study of Apomorphine Sublingual Film in Patients With Parkinson's Disease

A randomized thorough QT study was conducted to assess the effects of apomorphine sublingual film (SL‐APO) on corrected QT interval (QTc) and other cardiac conduction parameters in patients with Parkinson's disease (PD) and “OFF” episodes. Patients were titrated to an SL‐APO dose that resulted...

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Veröffentlicht in:	Clinical pharmacology in drug development 2022-09, Vol.11 (9), p.1068-1077
Hauptverfasser:	Stocchi, Fabrizio, Peckham, Elizabeth L., De Pandis, Maria Francesca, Sciarappa, Ken, Kleiman, Robert, Agbo, Felix, Olanow, C. Warren, Blum, David, Navia, Bradford
Format:	Artikel
Sprache:	eng
Schlagworte:	Apomorphine - adverse effects apomorphine sublingual film Double-Blind Method Electrocardiography Humans Moxifloxacin - adverse effects Parkinson Disease - drug therapy Parkinson's disease pharmacokinetics QT interval “OFF” episodes
Online-Zugang:	Volltext
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