Synthesis of Bis(β‐Oximinoalkyl)malonates and Their Catalytic Reductive Cyclization to Piperidines

Hitherto unknown bis(β‐oximinoalkyl)malonates were demonstrated to be convenient platforms for the synthesis of saturated N‐heterocycles. Upon heterogeneous catalytic hydrogenation, these dioximes undergo reductive cyclization to give substituted piperidine‐4,4’‐dicarboxylates, which are valuable bu...

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Veröffentlicht in:	Advanced synthesis & catalysis 2022-08, Vol.364 (15), p.2557-2564
Hauptverfasser:	Pospelov, Evgeny V., Boyko, Yaroslav D., Ioffe, Sema L., Sukhorukov, Alexey Yu
Format:	Artikel
Sprache:	eng
Schlagworte:	catalytic hydrogenation cyclizations Michael addition oximes Piperidine piperidines Substitutes
Online-Zugang:	Volltext
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