The Effect of Kebar Grass Extract (Biophytum petersianum Klotzch) on Total Growth of Ovarian Follicles on Mice (Mus Musculus) during Lactation period were Exposed by Carbofuran
The study aimed to know the effect of Kebar grass extraction amounts of mice (Mus musculus) follicles ovary exposed by carbofuran. This study was an experimental study with a completely randomized design. Forty two lactation mice used in this study were divided into seven groups, that were: C was co...
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| Veröffentlicht in: | Research journal of pharmacy and technology 2022-05, Vol.15 (5), p.2028-2034 |
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| container_title | Research journal of pharmacy and technology |
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| creator | K. Mulyadi, Athaya Suprayogi, Tri W. Mafruchati, Maslichah Mustofa, Imam P. Hestianah, Eka M. Ntoruru, Juliano M. Luqman, Epy |
| description | The study aimed to know the effect of Kebar grass extraction amounts of mice (Mus musculus) follicles ovary exposed by carbofuran. This study was an experimental study with a completely randomized design. Forty two lactation mice used in this study were divided into seven groups, that were: C was control (Aquadest), P1 was injected with carbofuran 1/4 LD50 (0.0125mg/day), P2 was injected with carbofuran 1/8 LD50 (0.00625mg/day), P3 was injected with carbofuran 1/4 LD50 (0.0125mg/day) and Kebar grass extract (0.135mg/day), P4 was injected with carbofuran 1/8 LD50 (0.00625mg/day) and Kebar grass extract (0.135mg/day), P5 was injected with carbofuran 1/4 LD50 (0.0125mg/day) and vitamin C (0.2ml/day) and P6 was injected with carbofuran 1/8 LD50 (0.00625mg/day) and vitamin C (0.2ml/day) with a treatment period of 14 days. Then on the 15day of treatment, mice were sacrificed, and the ovary was taken. Then, histology preparation with HE (Hematoxylin-eosin) staining was made, and follicles ovary were counted. Data were analyzed by One Way ANOVA followed by the Duncan test. This study showed that exposed carbofuran was a significant decrease in the growth of ovarian follicles (p |
| doi_str_mv | 10.52711/0974-360X.2022.00335 |
| format | Article |
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Mulyadi, Athaya ; Suprayogi, Tri W. ; Mafruchati, Maslichah ; Mustofa, Imam ; P. Hestianah, Eka ; M. Ntoruru, Juliano ; M. Luqman, Epy</creator><creatorcontrib>K. Mulyadi, Athaya ; Suprayogi, Tri W. ; Mafruchati, Maslichah ; Mustofa, Imam ; P. Hestianah, Eka ; M. Ntoruru, Juliano ; M. Luqman, Epy</creatorcontrib><description>The study aimed to know the effect of Kebar grass extraction amounts of mice (Mus musculus) follicles ovary exposed by carbofuran. This study was an experimental study with a completely randomized design. Forty two lactation mice used in this study were divided into seven groups, that were: C was control (Aquadest), P1 was injected with carbofuran 1/4 LD50 (0.0125mg/day), P2 was injected with carbofuran 1/8 LD50 (0.00625mg/day), P3 was injected with carbofuran 1/4 LD50 (0.0125mg/day) and Kebar grass extract (0.135mg/day), P4 was injected with carbofuran 1/8 LD50 (0.00625mg/day) and Kebar grass extract (0.135mg/day), P5 was injected with carbofuran 1/4 LD50 (0.0125mg/day) and vitamin C (0.2ml/day) and P6 was injected with carbofuran 1/8 LD50 (0.00625mg/day) and vitamin C (0.2ml/day) with a treatment period of 14 days. Then on the 15day of treatment, mice were sacrificed, and the ovary was taken. Then, histology preparation with HE (Hematoxylin-eosin) staining was made, and follicles ovary were counted. Data were analyzed by One Way ANOVA followed by the Duncan test. This study showed that exposed carbofuran was a significant decrease in the growth of ovarian follicles (p<0.05). The administration of the Kebar grass extraction exposure to carbofuran is proven to increase primary and secondary follicles. The Kebar grass extraction administration gave a better effect than vitamin C (p<0.05).</description><identifier>ISSN: 0974-3618</identifier><identifier>EISSN: 0974-360X</identifier><identifier>EISSN: 0974-306X</identifier><identifier>DOI: 10.52711/0974-360X.2022.00335</identifier><language>eng</language><publisher>Raipur: A&V Publications</publisher><subject>Antioxidants ; Breastfeeding & lactation ; Flavonoids ; Follicles ; Free radicals ; Histology ; Insecticides ; Ovaries ; Variance analysis ; Vitamin C ; Vitamin E</subject><ispartof>Research journal of pharmacy and technology, 2022-05, Vol.15 (5), p.2028-2034</ispartof><rights>Copyright A&V Publications May 2022</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c1735-8389470a6bbbc1cf3e3f92e8b2a564734b80d06f6f7fc15d4e494efca29eae53</citedby><cites>FETCH-LOGICAL-c1735-8389470a6bbbc1cf3e3f92e8b2a564734b80d06f6f7fc15d4e494efca29eae53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>K. Mulyadi, Athaya</creatorcontrib><creatorcontrib>Suprayogi, Tri W.</creatorcontrib><creatorcontrib>Mafruchati, Maslichah</creatorcontrib><creatorcontrib>Mustofa, Imam</creatorcontrib><creatorcontrib>P. Hestianah, Eka</creatorcontrib><creatorcontrib>M. Ntoruru, Juliano</creatorcontrib><creatorcontrib>M. Luqman, Epy</creatorcontrib><title>The Effect of Kebar Grass Extract (Biophytum petersianum Klotzch) on Total Growth of Ovarian Follicles on Mice (Mus Musculus) during Lactation period were Exposed by Carbofuran</title><title>Research journal of pharmacy and technology</title><description>The study aimed to know the effect of Kebar grass extraction amounts of mice (Mus musculus) follicles ovary exposed by carbofuran. This study was an experimental study with a completely randomized design. Forty two lactation mice used in this study were divided into seven groups, that were: C was control (Aquadest), P1 was injected with carbofuran 1/4 LD50 (0.0125mg/day), P2 was injected with carbofuran 1/8 LD50 (0.00625mg/day), P3 was injected with carbofuran 1/4 LD50 (0.0125mg/day) and Kebar grass extract (0.135mg/day), P4 was injected with carbofuran 1/8 LD50 (0.00625mg/day) and Kebar grass extract (0.135mg/day), P5 was injected with carbofuran 1/4 LD50 (0.0125mg/day) and vitamin C (0.2ml/day) and P6 was injected with carbofuran 1/8 LD50 (0.00625mg/day) and vitamin C (0.2ml/day) with a treatment period of 14 days. Then on the 15day of treatment, mice were sacrificed, and the ovary was taken. Then, histology preparation with HE (Hematoxylin-eosin) staining was made, and follicles ovary were counted. Data were analyzed by One Way ANOVA followed by the Duncan test. This study showed that exposed carbofuran was a significant decrease in the growth of ovarian follicles (p<0.05). The administration of the Kebar grass extraction exposure to carbofuran is proven to increase primary and secondary follicles. The Kebar grass extraction administration gave a better effect than vitamin C (p<0.05).</description><subject>Antioxidants</subject><subject>Breastfeeding & lactation</subject><subject>Flavonoids</subject><subject>Follicles</subject><subject>Free radicals</subject><subject>Histology</subject><subject>Insecticides</subject><subject>Ovaries</subject><subject>Variance analysis</subject><subject>Vitamin C</subject><subject>Vitamin E</subject><issn>0974-3618</issn><issn>0974-360X</issn><issn>0974-306X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNo9kc1OwzAMxysEEgj2CEiRuMBhIx9N0x5h2gZi0y47cIvS1GFFpSlJChtPxSOSDoQly5b184f8T5JLgiecCkJucSHSMcvw84RiSicYM8aPkrP_8vF_TvLTZOT9K46W5Zym-VnyvdkCmhkDOiBr0BOUyqGFU96j2S44FcvX97XttvvQv6EOAjhfqzbmT40NX3p7g2yLNjaoJrbZz7Adxqw_lIsUmtumqXUDfoBWtQZ0veo9iq77pvc3qOpd3b6gZdyjQh2hDlxtK_QJLp6166yHCpV7NFWutKZ3qr1IToxqPIz-4nmymc8204fxcr14nN4tx5oIxsc5y4tUYJWVZamJNgyYKSjkJVU8SwVLyxxXODOZEUYTXqWQFikYrWgBCjg7T65-x3bOvvfgg3y1vWvjRkmzQhDBBc4ixX8p7az3DozsXP2m3F4SLA_yyOH3ctBBDvLIgzzsBxWlhSQ</recordid><startdate>20220530</startdate><enddate>20220530</enddate><creator>K. Mulyadi, Athaya</creator><creator>Suprayogi, Tri W.</creator><creator>Mafruchati, Maslichah</creator><creator>Mustofa, Imam</creator><creator>P. Hestianah, Eka</creator><creator>M. Ntoruru, Juliano</creator><creator>M. Luqman, Epy</creator><general>A&V Publications</general><scope>AAYXX</scope><scope>CITATION</scope><scope>04Q</scope><scope>04S</scope><scope>04W</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope></search><sort><creationdate>20220530</creationdate><title>The Effect of Kebar Grass Extract (Biophytum petersianum Klotzch) on Total Growth of Ovarian Follicles on Mice (Mus Musculus) during Lactation period were Exposed by Carbofuran</title><author>K. Mulyadi, Athaya ; Suprayogi, Tri W. ; Mafruchati, Maslichah ; Mustofa, Imam ; P. Hestianah, Eka ; M. Ntoruru, Juliano ; M. Luqman, Epy</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1735-8389470a6bbbc1cf3e3f92e8b2a564734b80d06f6f7fc15d4e494efca29eae53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Antioxidants</topic><topic>Breastfeeding & lactation</topic><topic>Flavonoids</topic><topic>Follicles</topic><topic>Free radicals</topic><topic>Histology</topic><topic>Insecticides</topic><topic>Ovaries</topic><topic>Variance analysis</topic><topic>Vitamin C</topic><topic>Vitamin E</topic><toplevel>online_resources</toplevel><creatorcontrib>K. Mulyadi, Athaya</creatorcontrib><creatorcontrib>Suprayogi, Tri W.</creatorcontrib><creatorcontrib>Mafruchati, Maslichah</creatorcontrib><creatorcontrib>Mustofa, Imam</creatorcontrib><creatorcontrib>P. Hestianah, Eka</creatorcontrib><creatorcontrib>M. Ntoruru, Juliano</creatorcontrib><creatorcontrib>M. Luqman, Epy</creatorcontrib><collection>CrossRef</collection><collection>India Database</collection><collection>India Database: Business</collection><collection>India Database: Science & Technology</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><jtitle>Research journal of pharmacy and technology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>K. Mulyadi, Athaya</au><au>Suprayogi, Tri W.</au><au>Mafruchati, Maslichah</au><au>Mustofa, Imam</au><au>P. Hestianah, Eka</au><au>M. Ntoruru, Juliano</au><au>M. Luqman, Epy</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Effect of Kebar Grass Extract (Biophytum petersianum Klotzch) on Total Growth of Ovarian Follicles on Mice (Mus Musculus) during Lactation period were Exposed by Carbofuran</atitle><jtitle>Research journal of pharmacy and technology</jtitle><date>2022-05-30</date><risdate>2022</risdate><volume>15</volume><issue>5</issue><spage>2028</spage><epage>2034</epage><pages>2028-2034</pages><issn>0974-3618</issn><eissn>0974-360X</eissn><eissn>0974-306X</eissn><abstract>The study aimed to know the effect of Kebar grass extraction amounts of mice (Mus musculus) follicles ovary exposed by carbofuran. This study was an experimental study with a completely randomized design. Forty two lactation mice used in this study were divided into seven groups, that were: C was control (Aquadest), P1 was injected with carbofuran 1/4 LD50 (0.0125mg/day), P2 was injected with carbofuran 1/8 LD50 (0.00625mg/day), P3 was injected with carbofuran 1/4 LD50 (0.0125mg/day) and Kebar grass extract (0.135mg/day), P4 was injected with carbofuran 1/8 LD50 (0.00625mg/day) and Kebar grass extract (0.135mg/day), P5 was injected with carbofuran 1/4 LD50 (0.0125mg/day) and vitamin C (0.2ml/day) and P6 was injected with carbofuran 1/8 LD50 (0.00625mg/day) and vitamin C (0.2ml/day) with a treatment period of 14 days. Then on the 15day of treatment, mice were sacrificed, and the ovary was taken. Then, histology preparation with HE (Hematoxylin-eosin) staining was made, and follicles ovary were counted. Data were analyzed by One Way ANOVA followed by the Duncan test. This study showed that exposed carbofuran was a significant decrease in the growth of ovarian follicles (p<0.05). The administration of the Kebar grass extraction exposure to carbofuran is proven to increase primary and secondary follicles. The Kebar grass extraction administration gave a better effect than vitamin C (p<0.05).</abstract><cop>Raipur</cop><pub>A&V Publications</pub><doi>10.52711/0974-360X.2022.00335</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Research journal of pharmacy and technology, 2022-05, Vol.15 (5), p.2028-2034 |
| issn | 0974-3618 0974-360X 0974-306X |
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| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Antioxidants Breastfeeding & lactation Flavonoids Follicles Free radicals Histology Insecticides Ovaries Variance analysis Vitamin C Vitamin E |
| title | The Effect of Kebar Grass Extract (Biophytum petersianum Klotzch) on Total Growth of Ovarian Follicles on Mice (Mus Musculus) during Lactation period were Exposed by Carbofuran |
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