Novel LC–MS Method development and Validation for Characterization of Talazoparib, an Anti-cancer drug and its forced degradation behavior

The present work aimed to develop a novel liquid chromatography and mass spectrometry (LC-MS) method for the determination of Talazoparib (TZPB) in pharmaceutical forms. Analysis of TZPB was performed in mobile phase of Methanol, Acetonitrile and 0.2% Perchloric acid in the ratio of 70:28:02 (v/v) a...

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Veröffentlicht in:	Research journal of pharmacy and technology 2022-06, Vol.15 (6), p.2592-2598
Hauptverfasser:	Pakalapati, Srinivasarao, Douglas, Paul, Swamy Rumalla, Chidananda, Kaliyaperumal, Muralidharan
Format:	Artikel
Sprache:	eng
Schlagworte:	Accuracy Acids Calibration Cell cycle Chromatography Gas flow Molecular weight Pharmaceuticals Quality control
Online-Zugang:	Volltext
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