An activatable fluorescence probe for visualization of DAGL activity in hippocampal tissue of brain-injured mice

Diacylglycerol lipase (DAGL) is an important biosynthetic enzyme of endocannabinoid 2-arachidonoyl-glycerol (2-AG) that activates the endocannabinoid receptors to mediate basic biological processes, such as inflammation, pain sensation, epileptogenesis, synaptic plasticity, neuroprotection and adult...

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Veröffentlicht in:	Sensors and actuators. B, Chemical Chemical, 2022-09, Vol.367, p.132047, Article 132047
Hauptverfasser:	Zhang, Hongyi, Luo, Jiajie, Qiao, Zhen, An, Baoshuai, Wei, Ningning, Zhang, Yanru
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological activity Brain Chemical compounds Coumarin Diacylglycerol lipase Endocannabinoid Energy transfer Fluorescence resonance energy transfer Fluorescent indicators Fluorescent probe Glycerol Head injuries Rhodamine Selectivity Substrates
Online-Zugang:	Volltext
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