Genomics of disease risk in globally diverse populations

Risk of disease is multifactorial and can be shaped by socio-economic, demographic, cultural, environmental and genetic factors. Our understanding of the genetic determinants of disease risk has greatly advanced with the advent of genome-wide association studies (GWAS), which detect associations bet...

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Veröffentlicht in:	Nature reviews. Genetics 2019-09, Vol.20 (9), p.520-535
Hauptverfasser:	Gurdasani, Deepti, Barroso, Inês, Zeggini, Eleftheria, Sandhu, Manjinder S.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/1647/2217/2138 631/1647/2217/457 631/208/205 631/208/726/649 Agriculture Animal Genetics and Genomics Biomedical and Life Sciences Biomedicine Cancer Research Demographic aspects Demography Disease Gene Function Genetic diversity Genetic drift Genetic factors Genetic susceptibility Genetic variation Genome-wide association studies Genomics Health aspects Human Genetics International aspects Population Population genetics Review Article Risk assessment Translation
Online-Zugang:	Volltext
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