Dual functional amphiphilic sugar-coated AIE-active fluorescent organic nanoparticles for the monitoring and inhibition of insulin amyloid fibrillation based on carbohydrate-protein interactions

Amyloid-related diseases, such as Alzheimer's disease, are all considered to be related to the deposition of amyloid fibrils in the body. Insulin is a protein hormone that easily undergoes aggregation and fibrillation to form more toxic amyloid-like fibrils. So far, it is still challenging to d...

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Veröffentlicht in:Journal of materials chemistry. B, Materials for biology and medicine Materials for biology and medicine, 2022-07, Vol.1 (29), p.562-5611
Hauptverfasser: Ji, Yan-ming, Zhang, Wenyan, Zhang, Jing-dong, Li, Xia-fen, Yu, Fan-dong, Li, Cui-yun, Liu, Guang-jian, Xing, Guo-wen
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Sprache:eng
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