Parallel mechanochemical optimization - Buchwald-Hartwig C-N coupling as a test case

Buchwald-Hartwig aromatic amination has been chosen as a test case for reaction condition optimization in a mechanochemical setting. A parallel approach has allowed a fast investigation of different parameters. In particular, liquid-assisted grinding (LAG) as well as addition of a grinding auxiliary...

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Veröffentlicht in:	Green chemistry : an international journal and green chemistry resource : GC 2022-07, Vol.24 (14), p.552-557
Hauptverfasser:	Lemesre, Quentin, Wiesner, Thomas, Wiechert, Rainer, Rodrigo, Eduardo, Triebel, Sonja, Geneste, Hervé
Format:	Artikel
Sprache:	eng
Schlagworte:	Amination Green chemistry Grinding NMR Nuclear magnetic resonance Optimization
Online-Zugang:	Volltext
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