958-P: Associations between Effect of Body-Mass Index (BMI) and HbA1c among Children and Young Adults with Type 1 Diabetes: A U.S. Based Multicenter Study
Background: The primary objective of this U.S. based multi-center study was to examine the association of overweight and obesity with A1c levels for children and adolescents with type 1 diabetes (T1D) . Methods: Electronic health record data spanning 2017-2021 for children and adolescents from the T...
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| Veröffentlicht in: | Diabetes (New York, N.Y.) N.Y.), 2022-06, Vol.71 (Supplement_1) |
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| container_title | Diabetes (New York, N.Y.) |
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| creator | MEKHOUBAD, ALLISON B. HSIEH, SUSAN NOOR, NUDRAT EBEKOZIEN, OSAGIE ROMPICHERLA, SAKETH OSPELT, EMMA L. ROBERTS, ALISSA J. SANCHEZ, JANINE FERRO, DIANA MIYAZAKI, BRIAN LEE, JOYCE M. |
| description | Background: The primary objective of this U.S. based multi-center study was to examine the association of overweight and obesity with A1c levels for children and adolescents with type 1 diabetes (T1D) .
Methods: Electronic health record data spanning 2017-2021 for children and adolescents from the T1D Exchange Quality Improvement (T1DX-QI) Collaborative was analyzed. BMI percentiles were calculated using the Centers for Disease Control and Prevention growth curves, and children were categorized into normal weight, overweight, obese and severely obese groups. Normal weight was defined as a BMI < 85th percentile for age and sex. Overweight was defined as a BMI ≥ 85th to < 95th percentile. Obesity was defined as having a BMI |
| doi_str_mv | 10.2337/db22-958-P |
| format | Article |
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Methods: Electronic health record data spanning 2017-2021 for children and adolescents from the T1D Exchange Quality Improvement (T1DX-QI) Collaborative was analyzed. BMI percentiles were calculated using the Centers for Disease Control and Prevention growth curves, and children were categorized into normal weight, overweight, obese and severely obese groups. Normal weight was defined as a BMI < 85th percentile for age and sex. Overweight was defined as a BMI ≥ 85th to < 95th percentile. Obesity was defined as having a BMI <120% of the 95th percentile whereas severe obesity was defined as having BMI ≥120% of the 95th percentile. HbA1c levels and BMI were from last in-person encounter.
Results: Of 14,484 T1D patients aged < 18 years, 2,063 (14%) were underweight, 9,320 (65%) normal weight, 1,769 (12%) overweight, 977 (7%) obese and 333 were severely obese (2%) . More people of Black (12%) and Hispanic (18%) race/ethnicity were in the obese group relative to the normal weight group (8% and 10% respectively; p<0.001) . HbA1c levels were higher in the obese/severely obese group compared to normal weight patients (HbA1c Mean (SD) : Obese (9.1 (2.3)) /severely obese (9.1 (2.2) vs. Normal weight: 8.7 (2.0) ; p<0.001) .
Conclusion: In this extensive real-world study, we found obese children and adolescents with T1D were more likely of Black or Hispanic race/ethnicity and have higher HbA1c levels compared to those with healthy weight.]]></description><identifier>ISSN: 0012-1797</identifier><identifier>EISSN: 1939-327X</identifier><identifier>DOI: 10.2337/db22-958-P</identifier><language>eng</language><publisher>New York: American Diabetes Association</publisher><subject>Adolescents ; Body weight ; Children ; Diabetes ; Diabetes mellitus (insulin dependent) ; Electronic medical records ; Ethnicity ; Glucose ; Growth curves ; Hemoglobin ; Minority & ethnic groups ; Obesity ; Overweight ; Quality control ; Teenagers ; Underweight ; Young adults</subject><ispartof>Diabetes (New York, N.Y.), 2022-06, Vol.71 (Supplement_1)</ispartof><rights>Copyright American Diabetes Association Jun 2022</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c1043-6106e44060f3853c733eef4ea779f220275b080290ecf3294517ba3691945f633</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>MEKHOUBAD, ALLISON B.</creatorcontrib><creatorcontrib>HSIEH, SUSAN</creatorcontrib><creatorcontrib>NOOR, NUDRAT</creatorcontrib><creatorcontrib>EBEKOZIEN, OSAGIE</creatorcontrib><creatorcontrib>ROMPICHERLA, SAKETH</creatorcontrib><creatorcontrib>OSPELT, EMMA L.</creatorcontrib><creatorcontrib>ROBERTS, ALISSA J.</creatorcontrib><creatorcontrib>SANCHEZ, JANINE</creatorcontrib><creatorcontrib>FERRO, DIANA</creatorcontrib><creatorcontrib>MIYAZAKI, BRIAN</creatorcontrib><creatorcontrib>LEE, JOYCE M.</creatorcontrib><title>958-P: Associations between Effect of Body-Mass Index (BMI) and HbA1c among Children and Young Adults with Type 1 Diabetes: A U.S. Based Multicenter Study</title><title>Diabetes (New York, N.Y.)</title><description><![CDATA[Background: The primary objective of this U.S. based multi-center study was to examine the association of overweight and obesity with A1c levels for children and adolescents with type 1 diabetes (T1D) .
Methods: Electronic health record data spanning 2017-2021 for children and adolescents from the T1D Exchange Quality Improvement (T1DX-QI) Collaborative was analyzed. BMI percentiles were calculated using the Centers for Disease Control and Prevention growth curves, and children were categorized into normal weight, overweight, obese and severely obese groups. Normal weight was defined as a BMI < 85th percentile for age and sex. Overweight was defined as a BMI ≥ 85th to < 95th percentile. Obesity was defined as having a BMI <120% of the 95th percentile whereas severe obesity was defined as having BMI ≥120% of the 95th percentile. HbA1c levels and BMI were from last in-person encounter.
Results: Of 14,484 T1D patients aged < 18 years, 2,063 (14%) were underweight, 9,320 (65%) normal weight, 1,769 (12%) overweight, 977 (7%) obese and 333 were severely obese (2%) . More people of Black (12%) and Hispanic (18%) race/ethnicity were in the obese group relative to the normal weight group (8% and 10% respectively; p<0.001) . HbA1c levels were higher in the obese/severely obese group compared to normal weight patients (HbA1c Mean (SD) : Obese (9.1 (2.3)) /severely obese (9.1 (2.2) vs. Normal weight: 8.7 (2.0) ; p<0.001) .
Conclusion: In this extensive real-world study, we found obese children and adolescents with T1D were more likely of Black or Hispanic race/ethnicity and have higher HbA1c levels compared to those with healthy weight.]]></description><subject>Adolescents</subject><subject>Body weight</subject><subject>Children</subject><subject>Diabetes</subject><subject>Diabetes mellitus (insulin dependent)</subject><subject>Electronic medical records</subject><subject>Ethnicity</subject><subject>Glucose</subject><subject>Growth curves</subject><subject>Hemoglobin</subject><subject>Minority & ethnic groups</subject><subject>Obesity</subject><subject>Overweight</subject><subject>Quality control</subject><subject>Teenagers</subject><subject>Underweight</subject><subject>Young adults</subject><issn>0012-1797</issn><issn>1939-327X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNotkM9Kw0AQxhdRsFYvPsGAFxVS90-SzXpLa9VCiwUV9BQ2yaxNqdmaTdC8ik_rVmUOM8z8Zj7mI-SU0REXQl6VOeeBipJguUcGTAkVCC5f9smAUsYDJpU8JEfOrSmlsY8B-f6FryF1zhaVbitbO8ix_USsYWoMFi1YA2Nb9sFCOwezusQvOB8vZheg6xLu85QVoN9t_QaTVbUpG7-4G7zazrfSstu0Dj6rdgVP_RaBwU2lvQA6LwrPo8cRjLXDEhYerAqsW2zgse3K_pgcGL1xePKfh-T5dvo0uQ_mD3ezSToPCkZDEcSMxhiG_hsjkkgUUghEE6KWUhnOKZdRThPKFcXCCK7CiMlci1gxX5pYiCE5-7u7bexHh67N1rZrai-Z8TiJIsWSX-ryjyoa61yDJts21btu-ozRbOd9tvM-83ZmS_ED4_Vy6w</recordid><startdate>20220601</startdate><enddate>20220601</enddate><creator>MEKHOUBAD, ALLISON B.</creator><creator>HSIEH, SUSAN</creator><creator>NOOR, NUDRAT</creator><creator>EBEKOZIEN, OSAGIE</creator><creator>ROMPICHERLA, SAKETH</creator><creator>OSPELT, EMMA L.</creator><creator>ROBERTS, ALISSA J.</creator><creator>SANCHEZ, JANINE</creator><creator>FERRO, DIANA</creator><creator>MIYAZAKI, BRIAN</creator><creator>LEE, JOYCE M.</creator><general>American Diabetes Association</general><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>NAPCQ</scope></search><sort><creationdate>20220601</creationdate><title>958-P: Associations between Effect of Body-Mass Index (BMI) and HbA1c among Children and Young Adults with Type 1 Diabetes: A U.S. Based Multicenter Study</title><author>MEKHOUBAD, ALLISON B. ; HSIEH, SUSAN ; NOOR, NUDRAT ; EBEKOZIEN, OSAGIE ; ROMPICHERLA, SAKETH ; OSPELT, EMMA L. ; ROBERTS, ALISSA J. ; SANCHEZ, JANINE ; FERRO, DIANA ; MIYAZAKI, BRIAN ; LEE, JOYCE M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1043-6106e44060f3853c733eef4ea779f220275b080290ecf3294517ba3691945f633</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Adolescents</topic><topic>Body weight</topic><topic>Children</topic><topic>Diabetes</topic><topic>Diabetes mellitus (insulin dependent)</topic><topic>Electronic medical records</topic><topic>Ethnicity</topic><topic>Glucose</topic><topic>Growth curves</topic><topic>Hemoglobin</topic><topic>Minority & ethnic groups</topic><topic>Obesity</topic><topic>Overweight</topic><topic>Quality control</topic><topic>Teenagers</topic><topic>Underweight</topic><topic>Young adults</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>MEKHOUBAD, ALLISON B.</creatorcontrib><creatorcontrib>HSIEH, SUSAN</creatorcontrib><creatorcontrib>NOOR, NUDRAT</creatorcontrib><creatorcontrib>EBEKOZIEN, OSAGIE</creatorcontrib><creatorcontrib>ROMPICHERLA, SAKETH</creatorcontrib><creatorcontrib>OSPELT, EMMA L.</creatorcontrib><creatorcontrib>ROBERTS, ALISSA J.</creatorcontrib><creatorcontrib>SANCHEZ, JANINE</creatorcontrib><creatorcontrib>FERRO, DIANA</creatorcontrib><creatorcontrib>MIYAZAKI, BRIAN</creatorcontrib><creatorcontrib>LEE, JOYCE M.</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><jtitle>Diabetes (New York, N.Y.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>MEKHOUBAD, ALLISON B.</au><au>HSIEH, SUSAN</au><au>NOOR, NUDRAT</au><au>EBEKOZIEN, OSAGIE</au><au>ROMPICHERLA, SAKETH</au><au>OSPELT, EMMA L.</au><au>ROBERTS, ALISSA J.</au><au>SANCHEZ, JANINE</au><au>FERRO, DIANA</au><au>MIYAZAKI, BRIAN</au><au>LEE, JOYCE M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>958-P: Associations between Effect of Body-Mass Index (BMI) and HbA1c among Children and Young Adults with Type 1 Diabetes: A U.S. Based Multicenter Study</atitle><jtitle>Diabetes (New York, N.Y.)</jtitle><date>2022-06-01</date><risdate>2022</risdate><volume>71</volume><issue>Supplement_1</issue><issn>0012-1797</issn><eissn>1939-327X</eissn><abstract><![CDATA[Background: The primary objective of this U.S. based multi-center study was to examine the association of overweight and obesity with A1c levels for children and adolescents with type 1 diabetes (T1D) .
Methods: Electronic health record data spanning 2017-2021 for children and adolescents from the T1D Exchange Quality Improvement (T1DX-QI) Collaborative was analyzed. BMI percentiles were calculated using the Centers for Disease Control and Prevention growth curves, and children were categorized into normal weight, overweight, obese and severely obese groups. Normal weight was defined as a BMI < 85th percentile for age and sex. Overweight was defined as a BMI ≥ 85th to < 95th percentile. Obesity was defined as having a BMI <120% of the 95th percentile whereas severe obesity was defined as having BMI ≥120% of the 95th percentile. HbA1c levels and BMI were from last in-person encounter.
Results: Of 14,484 T1D patients aged < 18 years, 2,063 (14%) were underweight, 9,320 (65%) normal weight, 1,769 (12%) overweight, 977 (7%) obese and 333 were severely obese (2%) . More people of Black (12%) and Hispanic (18%) race/ethnicity were in the obese group relative to the normal weight group (8% and 10% respectively; p<0.001) . HbA1c levels were higher in the obese/severely obese group compared to normal weight patients (HbA1c Mean (SD) : Obese (9.1 (2.3)) /severely obese (9.1 (2.2) vs. Normal weight: 8.7 (2.0) ; p<0.001) .
Conclusion: In this extensive real-world study, we found obese children and adolescents with T1D were more likely of Black or Hispanic race/ethnicity and have higher HbA1c levels compared to those with healthy weight.]]></abstract><cop>New York</cop><pub>American Diabetes Association</pub><doi>10.2337/db22-958-P</doi></addata></record> |
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| source | EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Adolescents Body weight Children Diabetes Diabetes mellitus (insulin dependent) Electronic medical records Ethnicity Glucose Growth curves Hemoglobin Minority & ethnic groups Obesity Overweight Quality control Teenagers Underweight Young adults |
| title | 958-P: Associations between Effect of Body-Mass Index (BMI) and HbA1c among Children and Young Adults with Type 1 Diabetes: A U.S. Based Multicenter Study |
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