348-OR: Glycine and Branched-Chain Amino Acids (BCAA) Metabolic Signature in Youth with Obesity and Type 2 Diabetes (T2D)

BCAAs are associated with increased risk for T2D in adults, while glycine (Gly) appears to be have an inverse relationship. β-cell function is central to the development of T2D in youth. The relationship of Gly and BCAA to β-cell function in youth is not clear. We investigated the relationship betwe...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2022-06, Vol.71 (Supplement_1)
Hauptverfasser:	AYASH, HEBA EL, MOHAMMAD, MAHMOUD A., SHAWAR, REEM S., KANCHI, RUPA S., SHARMA, SUSAN, PUYAU, MAURICE R., COARFA, CRISTIAN, BACHA, FIDA
Format:	Artikel
Sprache:	eng
Schlagworte:	Adiponectin Adipose tissue Beta cells Blood glucose Body composition Body fat Diabetes Diabetes mellitus (non-insulin dependent) Dual energy X-ray absorptiometry Fasting Glucose tolerance Insulin Insulin secretion Isoleucine Magnetic resonance imaging Mass spectroscopy Metabolism Obesity Valine
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