178-LB: Prevalence of Vitamin D Deficiency among Patients with Type 2 Diabetes in Qingdao, China
The aim of the current study is to investigate the prevalence of vitamin D deficiency among patients with type 2 diabetes (T2DM) in a Chinese cohort. We enrolled 3025 patients with T2DM (aged 30-91 yrs) who were hospitalized in Qingdao Endocrine and Diabetes Hospital from Jan 2018 to Jan 2019. The e...
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| Veröffentlicht in: | Diabetes (New York, N.Y.) N.Y.), 2022-06, Vol.71 (Supplement_1) |
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| container_title | Diabetes (New York, N.Y.) |
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| creator | ZHANG, LEI WANG, JUN YANG, YUXIU DONG, YANHU |
| description | The aim of the current study is to investigate the prevalence of vitamin D deficiency among patients with type 2 diabetes (T2DM) in a Chinese cohort. We enrolled 3025 patients with T2DM (aged 30-91 yrs) who were hospitalized in Qingdao Endocrine and Diabetes Hospital from Jan 2018 to Jan 2019. The exclusion criteria were as follows: (1) with other types of diabetes; (2) pregnant or lactating females; (3) with acute complications of diabetes or other stress states, such as surgery and trauma; (4) with rheumatologic, serious hepatic, cardiac, renal failure, malignancy, and endocrine diseases that affect the metabolism of vitamin D. Serum level of 25-OH-vitamin D ≥ 30 ng/mL was defined as normal, 20 ng/mL ≤ 25-OH-vitamin D < 30 ng/mL as vitamin D insufficiency (VDI) , and serum 25-OH-vitamin D < 20 ng/mL as vitamin D deficiency (VDD) . The chi-square test was used for group comparison of VDD or VDI prevalence. In all subjects, the prevalence of VDI was 35%. Male patients had higher prevalence of VDI than female patients (40.0% vs. 28.9%, P |
| doi_str_mv | 10.2337/db22-178-LB |
| format | Article |
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In conclusion, VDI and VDD is prevalent in patients with type 2 diabetes. Poor glucose control is related to lower serum level of vitamin D. Future studies are required to verify if vitamin D supplementation could be beneficial in patients with diabetes.]]></description><identifier>ISSN: 0012-1797</identifier><identifier>EISSN: 1939-327X</identifier><identifier>DOI: 10.2337/db22-178-LB</identifier><language>eng</language><publisher>New York: American Diabetes Association</publisher><subject>Diabetes ; Diabetes mellitus (non-insulin dependent) ; Dietary supplements ; Endocrine disorders ; Females ; Malignancy ; Patients ; Renal failure ; Trauma ; Vitamin D ; Vitamin deficiency</subject><ispartof>Diabetes (New York, N.Y.), 2022-06, Vol.71 (Supplement_1)</ispartof><rights>Copyright American Diabetes Association Jun 2022</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c1060-f5c2bc984f6e5a77413cc70193c23f81f44ecfa826bfb019f71590fa8cc9bf8e3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids></links><search><creatorcontrib>ZHANG, LEI</creatorcontrib><creatorcontrib>WANG, JUN</creatorcontrib><creatorcontrib>YANG, YUXIU</creatorcontrib><creatorcontrib>DONG, YANHU</creatorcontrib><title>178-LB: Prevalence of Vitamin D Deficiency among Patients with Type 2 Diabetes in Qingdao, China</title><title>Diabetes (New York, N.Y.)</title><description><![CDATA[The aim of the current study is to investigate the prevalence of vitamin D deficiency among patients with type 2 diabetes (T2DM) in a Chinese cohort. We enrolled 3025 patients with T2DM (aged 30-91 yrs) who were hospitalized in Qingdao Endocrine and Diabetes Hospital from Jan 2018 to Jan 2019. The exclusion criteria were as follows: (1) with other types of diabetes; (2) pregnant or lactating females; (3) with acute complications of diabetes or other stress states, such as surgery and trauma; (4) with rheumatologic, serious hepatic, cardiac, renal failure, malignancy, and endocrine diseases that affect the metabolism of vitamin D. Serum level of 25-OH-vitamin D ≥ 30 ng/mL was defined as normal, 20 ng/mL ≤ 25-OH-vitamin D < 30 ng/mL as vitamin D insufficiency (VDI) , and serum 25-OH-vitamin D < 20 ng/mL as vitamin D deficiency (VDD) . The chi-square test was used for group comparison of VDD or VDI prevalence. In all subjects, the prevalence of VDI was 35%. Male patients had higher prevalence of VDI than female patients (40.0% vs. 28.9%, P<0.05) . The prevalence of VDD was 48.8% in total while female had higher prevalence than male patients (57.2% vs. 41.8%, P<0.001) . We found a clear trend toward decreasing serum vitamin D concentration with rising HbA1c levels (P<0.001 in male and P<0.003 in female) . Dividing the HbA1c into deciles showed a linear association.
In conclusion, VDI and VDD is prevalent in patients with type 2 diabetes. Poor glucose control is related to lower serum level of vitamin D. Future studies are required to verify if vitamin D supplementation could be beneficial in patients with diabetes.]]></description><subject>Diabetes</subject><subject>Diabetes mellitus (non-insulin dependent)</subject><subject>Dietary supplements</subject><subject>Endocrine disorders</subject><subject>Females</subject><subject>Malignancy</subject><subject>Patients</subject><subject>Renal failure</subject><subject>Trauma</subject><subject>Vitamin D</subject><subject>Vitamin deficiency</subject><issn>0012-1797</issn><issn>1939-327X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNotUE1PAjEQbYwmInryD0ziUVf7sbttvQn4lWwiJmi81W5poQR2oV00_HtLMHOYzJs3b2YeQpcE31LG-N20pjQjXGTV4Aj1iGQyY5R_HaMexmTfkfwUncW4wBiXKXro-8C-h3GwP3ppG2OhdfDpO73yDYxgZJ03PuE70Ku2mcFYd6nsIvz6bg6T3doChZHXte1shDTz7pvZVLc3MJz7Rp-jE6eX0V785z76eHqcDF-y6u35dfhQZYakQzJXGFobKXJX2kJznhNmDMfpBUOZE8TluTVOC1rWrk6w46SQOAHGyNoJy_ro6qC7Du1ma2OnFu02NGmloqUoCiFziRPr-sAyoY0xWKfWwa902CmC1d5CtbdQJVNUNWB_T2RiOQ</recordid><startdate>20220601</startdate><enddate>20220601</enddate><creator>ZHANG, LEI</creator><creator>WANG, JUN</creator><creator>YANG, YUXIU</creator><creator>DONG, YANHU</creator><general>American Diabetes Association</general><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>NAPCQ</scope></search><sort><creationdate>20220601</creationdate><title>178-LB: Prevalence of Vitamin D Deficiency among Patients with Type 2 Diabetes in Qingdao, China</title><author>ZHANG, LEI ; WANG, JUN ; YANG, YUXIU ; DONG, YANHU</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1060-f5c2bc984f6e5a77413cc70193c23f81f44ecfa826bfb019f71590fa8cc9bf8e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Diabetes</topic><topic>Diabetes mellitus (non-insulin dependent)</topic><topic>Dietary supplements</topic><topic>Endocrine disorders</topic><topic>Females</topic><topic>Malignancy</topic><topic>Patients</topic><topic>Renal failure</topic><topic>Trauma</topic><topic>Vitamin D</topic><topic>Vitamin deficiency</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>ZHANG, LEI</creatorcontrib><creatorcontrib>WANG, JUN</creatorcontrib><creatorcontrib>YANG, YUXIU</creatorcontrib><creatorcontrib>DONG, YANHU</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><jtitle>Diabetes (New York, N.Y.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>ZHANG, LEI</au><au>WANG, JUN</au><au>YANG, YUXIU</au><au>DONG, YANHU</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>178-LB: Prevalence of Vitamin D Deficiency among Patients with Type 2 Diabetes in Qingdao, China</atitle><jtitle>Diabetes (New York, N.Y.)</jtitle><date>2022-06-01</date><risdate>2022</risdate><volume>71</volume><issue>Supplement_1</issue><issn>0012-1797</issn><eissn>1939-327X</eissn><abstract><![CDATA[The aim of the current study is to investigate the prevalence of vitamin D deficiency among patients with type 2 diabetes (T2DM) in a Chinese cohort. We enrolled 3025 patients with T2DM (aged 30-91 yrs) who were hospitalized in Qingdao Endocrine and Diabetes Hospital from Jan 2018 to Jan 2019. The exclusion criteria were as follows: (1) with other types of diabetes; (2) pregnant or lactating females; (3) with acute complications of diabetes or other stress states, such as surgery and trauma; (4) with rheumatologic, serious hepatic, cardiac, renal failure, malignancy, and endocrine diseases that affect the metabolism of vitamin D. Serum level of 25-OH-vitamin D ≥ 30 ng/mL was defined as normal, 20 ng/mL ≤ 25-OH-vitamin D < 30 ng/mL as vitamin D insufficiency (VDI) , and serum 25-OH-vitamin D < 20 ng/mL as vitamin D deficiency (VDD) . The chi-square test was used for group comparison of VDD or VDI prevalence. In all subjects, the prevalence of VDI was 35%. Male patients had higher prevalence of VDI than female patients (40.0% vs. 28.9%, P<0.05) . The prevalence of VDD was 48.8% in total while female had higher prevalence than male patients (57.2% vs. 41.8%, P<0.001) . We found a clear trend toward decreasing serum vitamin D concentration with rising HbA1c levels (P<0.001 in male and P<0.003 in female) . Dividing the HbA1c into deciles showed a linear association.
In conclusion, VDI and VDD is prevalent in patients with type 2 diabetes. Poor glucose control is related to lower serum level of vitamin D. Future studies are required to verify if vitamin D supplementation could be beneficial in patients with diabetes.]]></abstract><cop>New York</cop><pub>American Diabetes Association</pub><doi>10.2337/db22-178-LB</doi></addata></record> |
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| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Diabetes Diabetes mellitus (non-insulin dependent) Dietary supplements Endocrine disorders Females Malignancy Patients Renal failure Trauma Vitamin D Vitamin deficiency |
| title | 178-LB: Prevalence of Vitamin D Deficiency among Patients with Type 2 Diabetes in Qingdao, China |
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