Comparative analysis of the transcriptome of T2DM Bama mini-pigs with T2DM patients

Objective To compare the transcriptional differences between the T2DM-susceptible and T2DM-tolerant Bama mini-pigs and to determine the utility of Bama mini-pigs as an animal model for T2DM by comparing the transcriptomes of the animals with T2DM patients. Methods The skeletal muscle transcriptomes...

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Veröffentlicht in:	International journal of diabetes in developing countries 2022-04, Vol.42 (2), p.236-244
Hauptverfasser:	Yan, Xueyu, Si, Jinglei, Zhong, Fangjie, Wu, Yanjun, Jiang, Qinyang, Guo, Yafen, Yang, Xiurong, Liang, Jing, Lan, Ganqiu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Calcium signalling Cardiac muscle Cardiomyopathy Cardiovascular diseases Comparative analysis Cytoskeleton Diabetes Dilated cardiomyopathy Family Medicine General Practice Health Administration Immune response Infectious diseases Medicine Medicine & Public Health Mitochondrial uncoupling protein 2 Muscle contraction Original Article Peroxisome proliferator-activated receptors Signal transduction Skeletal muscle Thyroid cancer TOR protein Transcriptomes
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