Engineered Bacteria with Genetic Circuits Accumulating Nanomagnets as MRI Contrast Agents (Small 26/2022)

Engineered Bacteria with Genetic Circuits Accumulating Nanomagnets as MRI Contrast Agents (Small 26/2022)

Engineered Bacteria In article number 2200537, Urartu Özgür Şafak Şeker and co‐workers design Escherichia coli bacteria as a cell factory to produce magnetite crystals inside or on the cell surface via synthetic biology tools. It is a promising strategy to overcome the side effects of conventional c...

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Veröffentlicht in:Small (Weinheim an der Bergstrasse, Germany) Germany), 2022-07, Vol.18 (26), p.n/a
Hauptverfasser: Yavuz, Merve, Ütkür, Mustafa, Kehribar, Ebru Şahin, Yağız, Ecrin, Sarıtaş, Emine Ülkü, Şeker, Urartu Özgür Şafak
Format: Artikel
Sprache:eng
Schlagworte:
Cancer
Coliforms
Contrast agents
E coli
genetic circuits
Hyperthermia
iron oxide nanoparticles
magnetic bacteria
magnetic resonance imaging contrast agents
nanomagnets
Nanotechnology
Side effects
synthetic biology
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Zusammenfassung:Engineered Bacteria In article number 2200537, Urartu Özgür Şafak Şeker and co‐workers design Escherichia coli bacteria as a cell factory to produce magnetite crystals inside or on the cell surface via synthetic biology tools. It is a promising strategy to overcome the side effects of conventional cancer treatment therapies on healthy cells by improving the in vivo cancer targeting for MRI detection, hyperthermia, and drug delivery.
ISSN:1613-6810
1613-6829
DOI:10.1002/smll.202270139