Raman spectroscopy analysis for monitoring of chemical composition of aspirin after exposure to plasma flame
A Raman spectroscopy method was optimised to examine the chemical changes of aspirin tablets after interaction with helium temperatures. Several aspirin tablets were exposed to plasma-assisted desorption ionisation flame for different times (10, 30, 50, 60, 180 and 300s) and then analysed by Raman s...
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Veröffentlicht in: | Spectroscopy Europe 2022-07, Vol.34 (5), p.18 |
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description | A Raman spectroscopy method was optimised to examine the chemical changes of aspirin tablets after interaction with helium temperatures. Several aspirin tablets were exposed to plasma-assisted desorption ionisation flame for different times (10, 30, 50, 60, 180 and 300s) and then analysed by Raman spectroscopy using optimal conditions. The changes in chemistry between exposed and fresh (without exposure to plasma) tablets were compared. The vibrational peaks of the aspirin molecule in the Raman spectrum were identified by checking the peak position. The results showed clear spectra with increases in intensity of vibrational peaks until 30s, whereas no spectra were measured for the exposed tablets to plasma flame after 50s. It can, therefore, be assumed that the chemistry structure of aspirin compound might be damaged by exposure to high temperature. |
doi_str_mv | 10.1255/sew.2022.a15 |
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Several aspirin tablets were exposed to plasma-assisted desorption ionisation flame for different times (10, 30, 50, 60, 180 and 300s) and then analysed by Raman spectroscopy using optimal conditions. The changes in chemistry between exposed and fresh (without exposure to plasma) tablets were compared. The vibrational peaks of the aspirin molecule in the Raman spectrum were identified by checking the peak position. The results showed clear spectra with increases in intensity of vibrational peaks until 30s, whereas no spectra were measured for the exposed tablets to plasma flame after 50s. It can, therefore, be assumed that the chemistry structure of aspirin compound might be damaged by exposure to high temperature.</description><identifier>ISSN: 2634-2561</identifier><identifier>ISSN: 0966-0941</identifier><identifier>EISSN: 2634-2561</identifier><identifier>EISSN: 1522-2349</identifier><identifier>DOI: 10.1255/sew.2022.a15</identifier><language>eng</language><publisher>Chichester: IM Publications LLP</publisher><subject>Aspirin ; Chemical composition ; Chemistry ; Exposure ; High temperature ; Plasma ; Raman spectroscopy ; Spectra ; Spectroscopic analysis ; Spectrum analysis ; Tablets ; Temperature</subject><ispartof>Spectroscopy Europe, 2022-07, Vol.34 (5), p.18</ispartof><rights>Copyright Wiley Subscription Services, Inc. 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The changes in chemistry between exposed and fresh (without exposure to plasma) tablets were compared. The vibrational peaks of the aspirin molecule in the Raman spectrum were identified by checking the peak position. The results showed clear spectra with increases in intensity of vibrational peaks until 30s, whereas no spectra were measured for the exposed tablets to plasma flame after 50s. It can, therefore, be assumed that the chemistry structure of aspirin compound might be damaged by exposure to high temperature.</description><subject>Aspirin</subject><subject>Chemical composition</subject><subject>Chemistry</subject><subject>Exposure</subject><subject>High temperature</subject><subject>Plasma</subject><subject>Raman spectroscopy</subject><subject>Spectra</subject><subject>Spectroscopic analysis</subject><subject>Spectrum analysis</subject><subject>Tablets</subject><subject>Temperature</subject><issn>2634-2561</issn><issn>0966-0941</issn><issn>2634-2561</issn><issn>1522-2349</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNpNkEtLxDAUhYMoOI7u_AEBt3bMo03bpYgvGBBE1-E2TTRD08Qkg86_N8O4cHVf5x44H0KXlKwoa5qbpL9XjDC2AtocoQUTvK5YI-jxv_4UnaW0IUTUPaELNL2CgxmnoFWOPikfdhhmmHbJJmx8xM7PNvto5w_sDVaf2lkFE1beBZ9stn7e7yEFWzQYTNYR659y20aNs8dhguQAmwmcPkcnBqakL_7qEr0_3L_dPVXrl8fnu9t1pWjb5Ypz1Y6a6m6kNWcCysSHUTFquIFB1b0aqeg564U2hg6DavtOA2_qtryzjvIlujr4hui_tjplufHbWFIlyURHOK-74rxE1weVKsFT1EaGaB3EnaRE7nnKwlPuecrCk_8C4Wlrgg</recordid><startdate>20220701</startdate><enddate>20220701</enddate><creator>Jamur, Jasim</creator><general>IM Publications LLP</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7U5</scope><scope>8FD</scope><scope>L7M</scope></search><sort><creationdate>20220701</creationdate><title>Raman spectroscopy analysis for monitoring of chemical composition of aspirin after exposure to plasma flame</title><author>Jamur, Jasim</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c178t-33c7de1e8d14326ac7d3bdc21f3fabc49cd1693296eff1bbc798ea35471782813</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Aspirin</topic><topic>Chemical composition</topic><topic>Chemistry</topic><topic>Exposure</topic><topic>High temperature</topic><topic>Plasma</topic><topic>Raman spectroscopy</topic><topic>Spectra</topic><topic>Spectroscopic analysis</topic><topic>Spectrum analysis</topic><topic>Tablets</topic><topic>Temperature</topic><toplevel>online_resources</toplevel><creatorcontrib>Jamur, Jasim</creatorcontrib><collection>CrossRef</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Technology Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><jtitle>Spectroscopy Europe</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jamur, Jasim</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Raman spectroscopy analysis for monitoring of chemical composition of aspirin after exposure to plasma flame</atitle><jtitle>Spectroscopy Europe</jtitle><date>2022-07-01</date><risdate>2022</risdate><volume>34</volume><issue>5</issue><spage>18</spage><pages>18-</pages><issn>2634-2561</issn><issn>0966-0941</issn><eissn>2634-2561</eissn><eissn>1522-2349</eissn><abstract>A Raman spectroscopy method was optimised to examine the chemical changes of aspirin tablets after interaction with helium temperatures. Several aspirin tablets were exposed to plasma-assisted desorption ionisation flame for different times (10, 30, 50, 60, 180 and 300s) and then analysed by Raman spectroscopy using optimal conditions. The changes in chemistry between exposed and fresh (without exposure to plasma) tablets were compared. The vibrational peaks of the aspirin molecule in the Raman spectrum were identified by checking the peak position. The results showed clear spectra with increases in intensity of vibrational peaks until 30s, whereas no spectra were measured for the exposed tablets to plasma flame after 50s. It can, therefore, be assumed that the chemistry structure of aspirin compound might be damaged by exposure to high temperature.</abstract><cop>Chichester</cop><pub>IM Publications LLP</pub><doi>10.1255/sew.2022.a15</doi></addata></record> |
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subjects | Aspirin Chemical composition Chemistry Exposure High temperature Plasma Raman spectroscopy Spectra Spectroscopic analysis Spectrum analysis Tablets Temperature |
title | Raman spectroscopy analysis for monitoring of chemical composition of aspirin after exposure to plasma flame |
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