A Combination of Recombinant HA1-and Nucleoprotein-Based Chitosan Nanoparticles Induces Early and Potent Immune Responses Against the H9N2 Influenza Virus

The effectiveness of inactivated H9N2 influenza vaccines is doubtful due to changes in antigenic regions of the virus hemagglutinin (HA) protein. One strategy for the development of the efficacious vaccine is the use of nanoparticles that display more immunogenic regions of the influenza virus. In t...

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Veröffentlicht in:	Viral immunology 2022-06, Vol.35 (5), p.365-374
Hauptverfasser:	Shahsavandi, Shahla, Ebrahimi, Mohammad Majid, Fotouhi, Fatemeh, Tebianian, Majid
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies CD4 antigen CD8 antigen Cell growth Cell proliferation Chitosan Hemagglutinins Immunization Immunogenicity Influenza Intranasal administration Lymphocytes T Nanoparticles Original Articles Physicochemical properties Surface charge Vaccines Viruses
Online-Zugang:	Volltext
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