Synthesis of novel pyrimido[4,5-d]pyrimidine derivatives from 5-acetyl-4-aminopyrimidines

Two routes were proposed for the synthesis of pyrimido[4,5- d ]pyrimidine derivatives from 5-acetyl-4-aminopyrimidines. Acylation of 5-acetyl-4-aminopyrimidines followed by cyclization by the action of NH4OAc made it possible to access pyrimido[4,5- d ]pyrimidines with alkyl, aryl, and hetaryl subst...

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Veröffentlicht in:Chemistry of heterocyclic compounds (New York, N.Y. 1965) N.Y. 1965), 2022-05, Vol.58 (4-5), p.243-250
Hauptverfasser: Komkov, Alexander V., Kozlov, Mikhail А., Prezent, Mikhail А., Dmitrenok, Andrey S., Kolotyrkina, Natalya G., Minyaev, Mikhail E., Zavarzin, Igor V.
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Sprache:eng
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