KLF6 Super-enhancer Regulates Cell Proliferation by Recruiting GATA2 and SOX10 in Human Hepatoma Cells

Super-enhancer consists of a large cluster of transcription enhancers that regulates the expression of genes playing an important role in the growth and development of malignant tumors. Recently, several attempts for the identification of super-enhancers have been made, but their functional role in...

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Veröffentlicht in:	Molecular biology (New York) 2022-06, Vol.56 (3), p.443-452
Hauptverfasser:	Kum Chol Ri, Ri, Myong Ryong, Kim, Kwang Hun, Choe, Sun Il, Ri, Ju Hua, Kim, Ji Hyon, Ri, Jong Ho
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biomedical and Life Sciences Cell proliferation CRISPR Enhancers Hepatoma Human Genetics Kinases Life Sciences Liver cancer Molecular Cell Biology siRNA Sox10 protein Transcription factors Tumor cells
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